Clinical practice algorithms: Medication management to reduce fall risk in the elderly - Part 3, benzodiazepines, cardiovascular agents, and antidepressants

Journal of the American Academy of Nurse Practitioners

Volumn 20, Issue 2, 2008, Pages 55-62

  Bulat, Tatjana ^a   Castle, Steven Charles ^b   Rutledge, Michelle ^a   Quigley, Patricia ^a  

^a VISN 8 Patient Safety Center   (United States)

^b VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

Elderly; Falls; Medications; Practice algorithm

Indexed keywords

ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; BENZODIAZEPINE DERIVATIVE; CARDIOVASCULAR AGENT;

AGED; ALGORITHM; ARTICLE; DECISION TREE; DRUG ADMINISTRATION; DRUG MONITORING; FALLING; GERIATRIC ASSESSMENT; GERIATRIC NURSING; HUMAN; METHODOLOGY; NURSE PRACTITIONER; NURSING; NURSING ASSESSMENT; ORGANIZATION AND MANAGEMENT; PATIENT EDUCATION; PATIENT SELECTION; PRACTICE GUIDELINE; SAFETY;

ACCIDENTAL FALLS; AGED; ALGORITHMS; ANTI-ANXIETY AGENTS; ANTIDEPRESSIVE AGENTS; BENZODIAZEPINES; CARDIOVASCULAR AGENTS; DECISION TREES; DRUG ADMINISTRATION SCHEDULE; DRUG MONITORING; GERIATRIC ASSESSMENT; GERIATRIC NURSING; HUMANS; NURSE PRACTITIONERS; NURSING ASSESSMENT; PATIENT EDUCATION AS TOPIC; PATIENT SELECTION; PRACTICE GUIDELINES AS TOPIC; SAFETY MANAGEMENT;

EID: 38949096745     PISSN: 10412972     EISSN: 17457599     Source Type: Journal    
DOI: 10.1111/j.1745-7599.2007.00285.x     Document Type: Article

References (55)

1. American Geriatrics Society, British Geriatrics Society and American Academy of Orthopaedic Surgeons Panel on Falls Prevention 2001). Guideline for the prevention of falls in older persons. Journal of the American Geriatric Society, 49, 664 672.
2. Bowles, N 1999). The Dephi technique. Nursing Standard, 13 (45 32 36.
3. Bulat, T., Castle, S. C., Rutledge, M. K. Quigley (2008). Clinical practice algorithms: Medication management to reduce fall risk in the elderly - Part 2, summary algorithm. Journal of the American Academy of Nurse Practitioners, this issue.
4. Campbell, A. J 1991). Drug treatment as a cause of falls in old age. A review of the offending agents. Drugs & Aging, 1, 289 301.
5. Campbell, A. J., Robertson, M. C., Gardner, M. M., Norton, R. N. Buchner, D. M 1999). Psychotropic medication withdrawal and a home-based exercise program to prevent falls: A randomized, controlled trial. Journal of the American Geriatrics Society, 47, 850 853.
6. Cooper, J 1997). Consultant pharmacist assessment and reduction of fall risk in nursing facilities. Consultant Pharmacist, 12, 1294 1304.
7. Cumming, R. G 1998). Epidemiology of medication-related falls and fractures in the elderly. Drugs & Aging, 12, 43 53.
8. Cumming, R. G., Miller, J. P., Kelsey, J. L., Davis, P., Arfken, C. L., Birge, S., et al 1991). Medications and multiple falls in elderly people: The St. Louis Oasis Study. Age & Aging, 3, 219 228.
9. Cutson, T. M., Gray, S. L., Hughes, M. A., Carson, S. W. Hanlon, J. T 1997). Effect of a single dose of diazepam on balance measures in older people. Journal of the American Geriatric Society, 45, 435 440.
10. De Mey, C., Michel, M. C., McEwen, J. Moreland, T 1998). A double-blind comparison of terazosin and tamsulosin on their differential effects on ambulatory blood pressure and nocturnal orthostatic stress testing. European Urology, 33, 481 488.
11. Department of Veterans Affairs 2002). VISN-Wide Development of an Evidence-Based Program to Prevent Falls, VISN 8 and VISN 22. Report No. NPI-20-006-1. Washington, DC : Author.
12. Draganich, L. F., Zacny, J., Klafta, J. Karrison, T 2001). The effects of antidepressants on obstructed and unobstructed gait in healthy elderly people. Journals of Gerontology Series A-Biological Sciences & Medical Sciences, 56, M36 M41.
13. Ebly, E. M., Hogan, D. B. Fung, T. S 1997). Potential adverse outcomes of psychotropic and narcotic drug use in Canadian seniors. Journal of Clinical Epidemiology, 50, 857 863.
14. Ensrud, K. E., Blackwell, T., Mangione, C. M., Bowman, P. J., Bauer, D. C., Schwartz, A., et al 2003). Study of Osteoporotic Fractures Research Group. Central nervous system active medications and risk for fractures in older women. Archives of Internal Medicine, 163, 949 957.
15. Fick, D. M., Cooper, J. W., Wade, W. E., Waller, J. L., Maclean, J. R. Beers, M. H 2003). Updating the Beers criteria for potentially inappropriate medication use in older adults. Archives of Internal Medicine, 163, 2716 2724.
16. Fisch, H. U., Baktir, G., Karlaganis, G., Minder, C. Bircher, J 1990). Excessive motor impairment two hours after triazolam in the elderly. European Journal of Clinical Pharmacology, 38, 229 232.
17. French, D. D., Campbell, R., Spehar, A., Cunningham, F., Bulat, T. Luther, S. L 2006). Drugs and falls in community-dwelling older people: A National Veterans Study. Clinical Therapeutics, 28, 619 630.
18. French, D. D., Chirikos, T. N., Spehar, A., Campbell, R., Means, H. Bulat, T 2005). Effect of concomitant use of benzodiazepines and other drugs on veterans population. Drug Safety, 28, 1141 1150.
19. Greenblatt, D. J., Harmatz, J. S. Shader, R. I 1991). Clinical pharmacokinetics of anxiolytics and hypnotics in the elderly. Therapeutic considerations. Clinical Pharmacokinetics, 21, 165 177.
20. Hart-Hughes, S., Quigley, P., Bulat, T., Palacios, P. Scott, S 2004). An interdisciplinary approach to reducing fall risks and falls. Journal of Rehabilitation, 70, 46 51.
21. Heitterachi, E., Lord, S. R., Meyerkort, P., McCloskey, I. Fitzpatrick, R 2002). Blood pressure changes on upright tilting predict falls in older people. Age Ageing, 31 (3 181 186.
22. Herings, R. M., Stricker, B. H., de Boer, A., Bakker, A. Sturmans, F 1995). Benzodiazepines and the risk of falling leading to femur fractures. Dosage more important than elimination half-life. Archives of Internal Medicine, 155, 1801 1807.
23. Joo, J. H., Lenze, E. J., Mulsant, B. H., Begley, A. E., Weber, E. M., Stack, J. A., et al 2002). Risk factors for falls during treatment of late-life depression. Journal of Clinical Psychiatry, 63, 936 941.
24. Jorm, A. F., Grayson, D., Creasey, H., Waite, L. Broe, G. A 2000). Long-term benzodiazepine use by elderly people living in the community. Australian & New Zealand Journal of Public Health, 24, 7 10.
25. Kallin, K., Gustafson, Y., Sandman, P. O. Karlsson, S 2004). Drugs and falls in older people in geriatric care settings. Aging Clinical and Experimental Research, 16, 270 276.
26. Leipzig, R. M., Cumming, R. G. Tinetti, M. E 1999a). Drugs and falls in older people: A systematic review and meta-analysis: I. Psychotropic drugs. Journal of American Geriatric Society, 47, 30 39.
27. Leipzig, R. M., Cumming, R. G. Tinetti, M. E 1999b). Drugs and falls in older people: A systematic review and meta-analysis: II. Cardiac and analgesic drugs. Journal of the American Geriatrics Society, 47, 40 50.
28. Lipsitz, L. A., Jonsson, P. V., Kelley, M. M. Koestner, J. S 1991). Causes and correlates of recurrent falls in ambulatory frail elderly. Journal of Gerontology, 46, M114 M122.
29. Llorente, M. D., David, D., Golden, A. G., Silverman, M.A 2000). Defining patterns of benzodiazepine use in older adults. Journal of Geriatric Psychiatry and Neurology, 13, 150 160.
30. Lord, S. R., Sambrook, P. N., Gilbert, C., Kelley, P. J., Nguyen, T., Webster, I. W., et al 1994). Postural stability, falls and fractures in the elderly: Results from the Dubbo Osteoporosis Epidemiology Study. Medical Journal of Australia, 160, 684 685, 688 691.
31. Lowe, F. C 1997). Coadministration of tamsulosin and three antihypertensive agents in patients with benign prostatic hyperplasia: Pharmacodynamic. Clinical Therapeutics, 19, 730 742.
32. Mendelson, W. B 1996). The use of sedative/hypnotic medication and its correlation with falling down in the hospital. Sleep, 19, 698 701.
33. National Sleep Foundation 2005). Sleeptionary™ definition of coping. Retrieved April 4, 2005, from http://www.sleepfoundation.org/ sleeptionary/index.php?id=19&subsecion=coping. Washington, DC : Author.
34. Neutel, C., Perry, S. Maxwell, C 2002). Medication use and risk of falls. Pharmacoepidemiology and Drug Safety, 11, 97 104.
35. No authors listed 1995). Guidelines for the evaluation and management of heart failure. Circulation, 92, 2764 2784.
36. No authors listed 1996). Consensus statement on the definition of orthostatic hypotension, pure autonomic failure and multiple system atrophy. Journal of the Neurological Sciences, 144, 218 219.
37. Ooi, W. L., Hossain, M. Lipsitz, L. A 2000). The association between orthostatic hypotension and recurrent falls in nursing home residents. American Journal of Medicine, 108, 106 111.
38. Pacher, P. Ungavi, Z 2001). Selective serotonin-reuptake inhibitor antidepressants increase the risk of falls and hip fractures in elderly people by inhibiting cardiovascular ion channels. Medical Hypotheses, 57, 469 471.
39. Passaro, A., Volpato, S., Romagnoni, F., Manzoli, N., Zuliani, G. Fellin, R 2000). Benzodiazepines with different half-life and falling in a hospitalized population: The GIFA study group. Gruppo Italiano di Farmacovigilanza nell'Anziano. Journal of Clinical Epidemiology, 53, 1222 1229.
40. Quigley, P., Bulat, T., Rutledge, M. K. Castle, S. C 2007). Clinical practice algorithm: Medication management to reduce fall risk in the elderly - Part 1. Journal of the American Academy of Nurse Practitioners, 19.
41. Ray, W. A., Griffin, M. R. Malcom, E 1991). Cyclic antidepressants and the risk of hip fracture. Archives of Internal Medicine, 151, 754 756.
42. Ray, W. A., Thapa, P. B. Gideon, P 2000). Benzodiazepines and the risk of falls in nursing home residents. Journal of American Geriatric Society, 48, 682 685.
43. Robin, D. W., Hasan, S. S., Edeki, T., Lichenstein, M. J., Shiavi, R. G., Wood, A., et al 1996). Increased baseline sway contributes to increased losses of balance in older people following triazolam. Journal of American Geriatric Society, 44, 300 304.
44. Ryynanen, O. P., Kivela, S. L., Honkanen, R., Laippala, P. Saano, V 1993). Medications and chronic diseases as risk factors for falling injuries in the elderly. Scandinavian Journal of Social Medicine, 21, 264 271.
45. Schwab, M., Roder, F., Aleker, T., Ammon, S., Thon, K. P., Eichelbaum, M., et al 2000). Psychotropic drug use, falls and hip fracture in the elderly. Aging (Milano), 12 (3 234 239.
46. Seymour, R. M. Routledge, P. A 1998). Important drug-drug interactions in the elderly. Drugs & Aging, 12, 485 494.
47. Sgadari, A., Lapane, K. L., Mor, V., Landi, F., Bernabei, R. Gambassi, G 2000). Oxidative and nonoxidative benzodiazepines and the risk of femur fracture. The systematic assessment of geriatric drug use via epidemiology study group. Journal of Clinical Psychopharmacology, 20, 234 239.
48. Smith, R 2003). Fall-contributing adverse effects of the most frequently prescribed drugs. Journal of the American Podiatric Medical Association, 93, 42 50.
49. Souchet, E., Lapeyere-Mestre, M. Montastruc, J. L 2005). Drug related falls: A study in the French Pharmacovigilance database. Pharmacoepidemiology and Drug Safety, 14 (1 11 16.
50. Thapa, P. B., Gideon, P., Cost, T. W., Milam, A. B. Ray, W. A 1998). Antidepressants and the risk of falls among nursing home residents. New England Journal of Medicine, 339, 875 882.
51. Tinetti, M 2003). Preventing falls in elderly persons. New England Journal of Medicine, 348, 42 49.
52. Tinetti, M. E., Liu, W. L. Claus, E. B 1993). Predictors and prognosis of inability to get up after falls among elderly persons. Journal of the American Medical Association, 269, 65 70.
53. Wang, P. S., Bohn, R. L., Glynn, R. J., Mogun, H. Avorn, J 2001). Zolpidem use and hip fractures in older people. Journal of American Geriatric Society, 49, 1685 1690.
54. Weiner, D. K., Hanlon, J. T. Studenski, S. A 1998). Effects of central nervous system polypharmacy on falls liability in community dwelling elderly. Gerontology, 44, 217 221.
55. Williams, C. M 2002). Using medications appropriately in older adults. American Family Physician, 66, 1917 1924.