Preventative and therapeutic potential of lipopolysaccharide from edible gram-negative bacteria to various diseases

Current Drug Therapy

Volumn 3, Issue 1, 2008, Pages 26-32

  Inagawa, Hiroyuki ^a,b,c,d   Nishizawa, Takashi ^b,d   Yoshioka, Noriko ^b   Taniguchi, Yoshie ^b   Kochchi, Chie ^b,c,d,e   Soma, Gen Ichiro ^b,c,d,e  

^a NATIONAL FISHERIES UNIVERSITY   (Japan)

^b TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

^d Research and Development Department Macrophi Inc   (Japan)

^e KAGAWA UNIVERSITY   (Japan)

Author keywords

Hygienic hypothesis; Innate immunity; IP PA1; LPS; Macrophage network; TLR4

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; BETA 1,3 GLUCAN; IMMUNOMODULATING AGENT; PANTOEA AGGLOMERANS LIPOPOLYSACCHARIDE; PICIBANIL; RECOMBINANT TUMOR NECROSIS FACTOR; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ACETOBACTER; ANALGESIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; CLINICAL EFFECTIVENESS; DIABETES MELLITUS; DRUG ABSORPTION; DRUG SAFETY; FOOD ANALYSIS; FOOD BIOTECHNOLOGY; FOOD PROCESSING; GRAM NEGATIVE BACTERIUM; HOMEOSTASIS; HUMAN; HYPERLIPIDEMIA; IMMUNOMODULATION; IMMUNOPOTENTIATION; IMMUNOREGULATION; INNATE IMMUNITY; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; SURVIVAL RATE; ULCERATIVE COLITIS; XANTHOMONAS;

EID: 38949088892     PISSN: 15748855     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488508783331243     Document Type: Review

References (55)

1. Ross JA, Auger MJ. In: Burke B, Lewis CE Ed, The macrophage. New York, Oxford University Press. 2002; 3-72.
2. Nakata K, Inagawa H, Nishizawa T, et al. Unique molecular characteristics of the environmental responses of mucosal macrophages. Anticancer Res 2006; 26: 4009-14.
3. Nakata K, Inagawa H, Nishizawa T, Kohchi C, Soma GI. Specific messenger RNA expression for sigual transduction molecules by lipopolysaccharide in intestinal macrophages. Clin Exp Immunol 2006; 143: 484-93.
4. Nakata K, Inagawa H, Nishizawa T, et al. Inherent potential for production of tumor necrosis factor-alpha by human intestinal macrophages. Int J Colorectal Dis 2006; 21: 339-47.
5. Tada T. The immune system as a supersystem. Annu Rev Immunol 1997; 15: 1-13.
6. Soma IG, Nishizawa T, Inagawa H, et al. Bidirectional feedback regulation on 17 kD tumor necrosis factor (TNF) production by 26 kD membrane-bound TNF precursor. J Inflamm 1995; 47: 52-60.
7. Tanabe Y, Kohchi C, Kitahara-Tanabe N, Mizuno D, Soma G. Involvement of 26-kDa membrane-bound tumour necrosis factor precursor in bidirectional feedback regulation on 17-kDa tumour necrosis factor production after stimulation by lipopolysaccharide. Cytokine 1998; 10: 82-92.
8. Kohchi C, Noguchi Y, Tanabe Y, Mizuno D, Soma G. Constitutive expression of TNF-alpha and -beta genes in mouse embryo: roles of cytokines as regulator and effector on development. Int J Biochem 1994; 26: 111-9.
9. Kohchi C, Tanabe Y, Noguchi K, Mizuno D, Soma G. Induction of differentiation in embryonic stem cells by 26-kD membrane-bound tumor necrosis factor (TNF) and 17-kD five TNF. In Vivo 1996; 10: 19-27.
10. Kohchi C, Inagawa H, Hino M, et al. Utilization of macrophages in anticancer therapy: the macrophage network theory. Anticancer Res 2004; 24: 3311-20.
11. Kohchi C, Inagawa H, Nishizawa T, Yamaguchi T, Nagai S, Soma G. Applications of lipopolysaccharide derived from Pantoea agglomerans (IP-PA1) for health care based on macrophage network theory. J Biosci Bioeng 2006; 102: 485-96.
12. Mizuno D, Soma G. Oral or percutaneous administration of lipopolysaccharide of small molecular size may cum various intractable diseases: a new version of Coley's toxin. Mol Biother 1992; 4: 166-9.
13. Becker KG. Autism, asthma, inflammation, and the hygiene hypothesis. Med Hypotheses 2007; [Epub ahead of print].
14. Metchnikoff E. In: Lepons sur la Pathologie compare d'Inflammation. Paris, Masson. 1892.
15. Akira S. TLR signaling. Curr Top Microbiol Immunol 2006; 311: 1-16.
16. Messmer UK, Pfeilschifter J. New insights into the mechanism for clearance of apoptotic cells. Bioessays 2000; 22: 878-81.
17. Somersan S, Bhardwaj N. Tethering and tickling: a new role for the phosphatidylserine receptor. J Cell Biol 2001; 155: 501-4.
18. Ren H, Shen J, Tomiyama-Miyaji C, et al. Augmentation of innate immunity by low-dose irradiation. Cell Immunol 2006; 244: 50-6.
19. Yamasu Y, Shimada Y, Sakaizumi M, Soma G, Mizuno D. Activation of the systemic production of tumor necrosis factor after exposure to acute stress. Eur Cytokine Netw 1992; 3: 391-8.
20. Van Rooijen N, Sanders A. Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods 1994; 174: 83-93.
21. Nakamura Y, Aramaki Y, Kakiuchi T. A mouse model for postoperative fatal enteritis due to Staphylococcus infection. J Surg Res 2001; 96: 35-43.
22. Nakamoto T, Yoshimura H, Honda T, et al. Treatments for the activating macrophages that reduces surgical stress and postoperative mortalities from bacterial infections and tumor metastases. In Vivo 2007; 21: 357-64.
23. Halvorsen L, Roth R, Gunther RA, Firoozmand E, Buoncristiani AM, Kramer GC. Liver hemodynamics during portal venous endotoxemia in swine. Circ Shock 1993; 41: 166-75.
24. Satoh M, Iwahori T, Sugawara N, Yamazaki M. Liver argininosuccinate synthase binds to bacterial lipopolysaccharides and lipid A and inactivates their biological activities. J Endotoxin Res 2006; 12: 21-38.
25. Nishizawa T, Inagawa H, Oshima. H, et al. Homeostasis as regulated by activated macrophage. I. Lipopolysaccharide (LPS) from wheat flour: isolation, purification and some biological activities. Chem Pharm Bull (Tokyo) 1992; 40: 479-83.
26. Inagawa H, Satoh M, Oshima H, Mizuno D. Combination of commercial anticancer products (leninan and OK-432) induces endogenous TNF. Igaku-no-ayumi (Japanese) 1986; 138: 783-4.
27. Guencheva G, Popova P, Davidkova G, et al. Determination of cytokine release after in vivo and in vitro administration of Deodan (a preparation from Lactobacillus bulgaricus "LB51") by the rabbit pyrogen test. Int J Immunopharmacol 1992; 14: 1429-36.
28. Kariluoto S, Aittamaa M, Korhola M, Salovaara H, Vahteristo L, Piironen V. Effects of yeasts and bacteria on the levels of folates in rye sourdoughs. Int J Food Microbiol 2006; 106: 137-43.
29. Taniguchi Y, Nishizawa T, Kohchi C, et al. Identification and characterization of lipopolysaccharide in acetic acid bacteria. Anticancer Res 2006; 26: 3997-4002.
30. Inagawa H, Nishizawa T, Tsukioka D, et al. Homeostasis as regulated by activated macrophage. II. LPS of plant origin other than wheat flour and their concomitant bacteria. Chem Pharm Bull (Tokyo) 1992; 40: 994-7.
31. Rietschel ET, Kirikae T, Schade FU, et al. Bacterial endotoxin: molecular relationships of structure to activity and function. FASEB J 1994; 8: 217-25.
32. Buwitt-Beckmann U, Heine H, Wiesmuller KH, et al. Toll-like receptor 6-independent signaling by diacylated lipopeptides. Eur J Immunol 2005; 35: 282-9.
33. Casale TB, Kessler J, Romero FA. Safety of the intranasal toll-like receptor 4 agonist CRX-675 in allergic rhinitis. Ann Allergy Asthma Immunol 2006; 97: 454-6.
34. Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 2004; 118: 229-41.
35. Ayabe T, Satchell DP, Wilson CL, Parks WC, Selsted ME, Ouellette AJ. Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria. Nat Immunol 2000; 1: 113-8.
36. Biragyn A, Ruffini PA, Leifer CA, et al. Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2. Science 2002; 298: 1025-9.
37. Vora P, Youdim A, Thomas LS, et al. Beta-defensin-2 expression is regulated by TLR signaling in intestinal epithelial cells. J Immunol 2004; 173: 5398-405.
38. Inagawa H, Saitoh F, Iguchi M, et al. Homeostasis as regulated by activated macrophage. III. Protective effect of LPSw (lipopolysaccharide (LPS) of wheat flour) on gastric ulcer in mice as compared with those of other LPS from various sources. Chem Pharm Bull (Tokyo) 1992; 40: 998-1000.
39. Inagawa H, Nishizawa T, Honda T, Nakamoto T, Takagi K, Soma G. Mechanisms by which chemotherapeutic agents augment the antitumor effects of tumor necrosis factor: involvement of the pattern shift of cytokines from Th2 to Th1 in tumor lesions. Anticancer Res 1998; 18: 3957-64.
40. Suzuki J, Nishizawa T, Inagawa H, et al. Homeostasis as regulated by activated macrophage. IX. Enhancement effect of LPSw (a lipopolysaccharide from wheat flour) on hen egg-laying and breaking strength of eggshell. Chem Pharm Bull (Tokyo) 1992; 40: 1274-6.
41. Iguchi M, Inagawa H, Nishizawa T, et al. Homeostasis as regulated by activated macrophage. V. Suppression of diabetes mellitus in non-obese diabetic mice by LPSw (a lipopolysaccharide from wheat flour). Chem Pharm Bull (Tokyo) 1992; 40: 1004-6.
42. Okutomi T, Nishizawa T, Inagawa H, et al. Inhibition of morphine dependence by a lipopolysaccharide from Pantoea agglomerans. Eur Cytokine Netw 1992; 3: 417-20.
43. Suzuki Y, Kobayashi A, Nishizawa T, et al. Homeostasis as regulated by activated macrophage. VI. Protective efrect of LPSw (a lipopolysaccharide from wheat flour) against acute infection by Toxoplasma gondii in mice. Chem Pharm Bull (Tokyo) 1992; 40: 1266-7.
44. Okutomi T, Nishizswa T, Inagawa H, et al. Homeostasis as regulated by activated macrophage. VII. Suppression of serum cholesterol level by LPSw (a lipopolysaccharide from wheat flour) in WHHL (Watanabe heritable hyperlipidemic) rabbit. Chem Pharm Bull (Tokyo) 1992; 40: 1268-70.
45. Kawashima K, Endo H, Nishizawa T, et al. Homeostasis as regulated by activated macrophage. VIII. LPSw (a lipopolysaccharide from wheat flour) can regulate bone resorption of chick embryo. Chem Pharm Bull (Tokyo) 1992; 40: 1271-3.
46. Takahashi Y, Kondo M, Itami T, et al. Enhancement of disease resistance against penaeid acute viraemia and induction of virus-inactivating activity in haemolymph of kuruma shrimp, Penaeus japonicus, by oral administration of Pantoea agglomerans lipopolysaccharide (LPS). Fish Shellfish Immunol 2000; 10: 555-8.
47. Soma G, Mizuno D. In: Fiers W, Buurman WA Ed, Molecular and Cellular Biology and Clinical Relevance. Basel, Karger. 1993; 203-20.
48. Tsukioka D, Nishizawa T, Miyase T, et al. Structural characterization of lipid A obtained from Pantoea agglomerans lipopolysaccharide. FEMS Microbiol Lett 1997; 149: 239-44.
49. Asia CA, Jr., Adachi K. Isolation of endophytic diazotroph Pantoea agglomerans and nondiazotroph Enterobacter asburiae from sweetpotato stem in Japan. Lett Appl Microbiol 2004; 38: 19-23.
50. Nunes C, Usall J, Teixido N, Vinas I. Biological control of post-harvest pear diseases using a bacterium, Pantoea agglomerans CPA-2. Int J Food Microbiol 2001; 70: 53-61.
51. Nunes C, Usall J, Teixido N, Fons E, Vinas I. Post-harvest biological control by Pantoea agglomerans (CPA-2) on Golden Delicious apples. J Appl Microbiol 2002; 92: 247-55.
52. Enya J, Shinohara H, Yoshida S, et al. Culturable leaf-associated bacteria on tomato plants and their potential as biological control agents. Microb Ecol 2007; 53: 524-36.
53. Verma SC, Ladha JK, Tripathi AK. Evaluation of plant growth promoting and colonization ability of endophytic diazotrophs from deep water rice. J Biotechnol 2001; 91: 127-41.
54. Kimura F. Molecular target drug discovery. Intern Med 2007; 46: 87-9.
55. Hutcheson IR, Knowlden JM, Jones HE, et al. Inductive mechanisms limiting response to anti-epidermal growth factor receptor therapy. Endocr Relat Cancer 2006; 13: S89-97.