Controlling poly(β-amino ester) network properties through macromer branching

Acta Biomaterialia

Volumn 4, Issue 2, 2008, Pages 207-217

  Brey, Darren M ^a   Ifkovits, Jamie L ^a   Mozia, Robert I ^a   Katz, Josh S ^a   Burdick, Jason A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Biodegradable; Branching; Macromer; Photopolymerization; Tissue engineering

Indexed keywords

BIOMATERIALS; BIOMECHANICS; CELL ADHESION; CONTROLLED DRUG DELIVERY; ELASTIC MODULI; ESTERS; GLASS TRANSITION; PHOTOPOLYMERIZATION; SCAFFOLDS (BIOLOGY); TISSUE;

AMINO ESTERS; BIODEGRADABLE; BRANCHING; DEGRADABLE BIOMATERIALS; MACROMERS; NETWORK PROPERTIES; PHOTO POLYMERIZATION; POROUS SCAFFOLD; SIMPLE++; TISSUES ENGINEERINGS;

DEGRADATION;

ACRYLIC ACID DERIVATIVE; BIOMATERIAL; MONOMER; POLY(BETA AMINO ESTER); POLYMER; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL SPREADING; CHEMICAL STRUCTURE; COMPRESSIVE STRENGTH; CONTROLLED STUDY; DEGRADATION; FILM; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; OSTEOBLAST; POLYMERIZATION; PRIORITY JOURNAL; SYNTHESIS; TEMPERATURE; TENSILE STRENGTH; TISSUE ENGINEERING;

EID: 38949085159     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2007.10.002     Document Type: Article

References (37)

1. Anseth K.S., Goodner M.D., Reill M.A., Kannurpatti A.R., Newman S.M., and Bowman C.N. The influence of comonomer composition on dimethacrylate resin properties for dental composites. J Dent Res 75 (1996) 1607-1612
2. Bryant S.J., Nuttelman C.R., and Anseth K.S. Cytocompatibility of UV and visible light photoinitiating systems on cultured nih/3t3 fibroblasts in vitro. J Biomater Sci Polym Ed 11 (2000) 439-457
3. Burdick J.A., Peterson A.J., and Anseth K.S. Conversion and temperature profiles during the photoinitiated polymerization of thick orthopaedic biomaterials. Biomaterials 22 (2001) 1779-1786
4. Khademhosseini A., Eng G., Yeh J., Fukuda J., Blumling J., Langer R., et al. Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment. J Biomed Mater Res Part A 79A (2006) 522-532
5. Liu V.A., and Bhatia S.N. Three-dimensional photopatterning of hydrogels containing living cells. Biomed Microdev 4 (2002) 257-266
6. Anseth K.S., Shastri V.R., and Langer R. Photopolymerizable degradable polyanhydrides with osteocompatibility. Nature Biotechnol 17 (1999) 156-159
7. Fisher J.P., Holland T.A., Dean D., Engel P.S., and Mikos A.G. Synthesis and properties of photocross-linked poly(propylene fumarate) scaffolds. J Biomater Sci Polym Ed 12 (2001) 673-687
8. Burdick J.A., Mason M.N., Hinman A.D., Thorne K., and Anseth K.S. Delivery of osteoinductive growth factors from degradable peg hydrogels influences osteoblast differentiation and mineralization. J Control Release 83 (2002) 53-63
9. Sawhney A.S., Pathak C.P., and Hubbell J.A. Bioerodible hydrogels based on photopolymerized poly(ethylene glycol)-co-poly(alpha-hydroxy acid) diacrylate macromers. Macromolecules 26 (1993) 581-587
10. Chung C., Mesa J., Miller G.J., Randolph M.A., Gill T.J., and Burdick J.A. Effects of auricular chondrocyte expansion on neocartilage formation in photocrosslinked hyaluronic acid networks. Tissue Eng 12 (2006) 2665-2673
11. Chung C., Mesa J., Randolph M.A., Yaremchuk M., and Burdick J.A. Influence of gel properties on neocartilage formation by auricular chondrocytes photoencapsulated in hyaluronic acid networks. J Biomed Mater Res Part A 77A (2006) 518-525
12. Elisseeff J., McIntosh W., Anseth K., Riley S., Ragan P., and Langer R. Photoencapsulation of chondrocytes in poly(ethylene oxide)-based semi-interpenetrating networks. J Biomed Mater Res 51 (2000) 164-171
13. DeLong S.A., Moon J.J., and West J.L. Covalently immobilized gradients of bfgf on hydrogel scaffolds for directed cell migration. Biomaterials 26 (2005) 3227-3234
14. Hillwest J.L., Chowdhury S.M., Slepian M.J., and Hubbell J.A. Inhibition of thrombosis and intimal thickening by in situ photopolymerization of thin hydrogel barriers. P Natl Acad Sci USA 91 (1994) 5967-5971
15. Anseth K.S., Metters A.T., Bryant S.J., Martens P.J., Elisseeff J.H., and Bowman C.N. In situ forming degradable networks and their application in tissue engineering and drug delivery. J Control Release 78 (2002) 199-209
16. Piantino J., Burdick J.A., Goldberg D., Langer R., and Benowitz L.I. An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury. Exp Neurol 201 (2006) 359-367
17. Beebe D.J., Moore J.S., Bauer J.M., Yu Q., Liu R.H., Devadoss C., et al. Functional hydrogel structures for autonomous flow control inside microfluidic channels. Nature 404 (2000) 588
18. Anderson D.G., Tweedie C.A., Hossain N., Navarro S.M., Brey D.M., Van Vliet K.J., et al. A combinatorial library of photocrosslinkable and degradable materials. Adv Mater 18 (2006) 2614-2618
19. Brey DM, Erickson IE, Burdick JA. Influence of macromer molecular weight and chemistry on poly(β-amino ester) network properties and initial cell interactions. J Biomed Mater Res Part A (in press).
20. Burdick J.A., Lovestead T.M., and Anseth K.S. Kinetic chain lengths in highly cross-linked networks formed by the photoinitiated polymerization of divinyl monomers: A gel permeation chromatography investigation. Biomacromolecules 4 (2003) 149-156
21. Soltz M.A., and Ateshian G.A. Experimental verification and theoretical prediction of cartilage interstitial fluid pressurization at an impermeable contact interface in confined compression. J Biomech 31 (1998) 927-934
22. Xu J.W., Shi W.F., and Pang W.M. Synthesis and shape memory effects of Si--O--Si cross-linked hybrid polyurethanes. Polymer 47 (2006) 457-465
23. Mikos A.G., Thorsen A.J., Czerwonka L.A., Bao Y., Langer R., Winslow D.N., et al. Preparation and characterization of poly(l-lactic acid) foams. Polymer 35 (1994) 1068-1077
24. Bryant S.J., Cuy J.L., Hauch K.D., and Ratner B.D. Photo-patterning of porous hydrogels for tissue engineering. Biomaterials 28 (2007) 2978-2986
25. Kulkarni A.S., and Beaucage G. Quantification of branching in disordered materials. J Polym Sci Part B-Polym Phys 44 (2006) 1395-1405
26. Li X.R., Su Y.L., Chen Q.Y., Lin Y., Tong Y.J., and Li Y.S. Synthesis and characterization of biodegradable hyperbranched poly(ester-amide)s based on natural material. Biomacromolecules 6 (2005) 3181-3188
27. Nivasu V.M., Yarapathi R.V., and Tammishetti S. Synthesis, UV photo-polymerization and degradation study of PEG containing polyester polyol acrylates. Polym Adv Technol 15 (2004) 128-133
28. Tian J.H., Yu W., and Zhou C.X. The preparation and rheology characterization of long chain branching polypropylene. Polymer 47 (2006) 7962-7969
29. McKee M.G., Unal S., Wilkes G.L., and Long T.E. Branched polyesters: recent advances in synthesis and performance. Prog Polym Sci 30 (2005) 507-539
30. Burdick J.A., and Anseth K.S. Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering. Biomaterials 23 (2002) 4315-4323
31. Discher D.E., Janmey P., and Wang Y.L. Tissue cells feel and respond to the stiffness of their substrate. Science 310 (2005) 1139-1143
32. Hern D.L., and Hubbell J.A. Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing. J Biomed Mater Res 39 (1998) 266-276
33. Burdick J.A., Philpott L.M., and Anseth K.S. Synthesis and characterization of tetrafunctional lactic acid oligomers: a potential in situ forming degradable orthopaedic biomaterial. J Polym Sci Part A-Polym Chem 39 (2001) 683-692
34. Karageorgiou V., and Kaplan D. Porosity of 3d biomaterial scaffolds and osteogenesis. Biomaterials 26 (2005) 5474-5491
35. Freed L.E., Vunjaknovakovic G., Biron R.J., Eagles D.B., Lesnoy D.C., Barlow S.K., et al. Biodegradable polymer scaffolds for tissue engineering. Bio-Technology 12 (1994) 689-693
36. Yang S.F., Leong K.F., Du Z.H., and Chua C.K. The design of scaffolds for use in tissue engineering Part 1. Traditional factors. Tissue Eng 7 (2001) 679-689
37. Stachowiak A.N., Bershteyn A., Tzatzalos E., and Irvine D.J. Bioactive hydrogels with an ordered cellular structure combine interconnected macroporosity and robust mechanical properties. Adv Mater 17 (2005) 399-403