Placental insufficiency in early gestation is associated with hypospadias

Journal of Pediatric Surgery

Volumn 43, Issue 2, 2008, Pages 358-361

  Fujimoto, Takao ^a   Suwa, Tomohide ^a   Kabe, Kazuhiko ^a   Adachi, Tomoko ^a   Nakabayashi, Masao ^a   Amamiya, Teruko ^b  

^a Imperial Gift Foundation   (Japan)

^b Shiseikai Daini Hospital   (Japan)

Author keywords

Hypospadias; Intrauterine growth retardation; Low birth weight infants; Pathophysiology; Placental dysfunction

Indexed keywords

ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FETUS GROWTH; GESTATIONAL AGE; HISTOPATHOLOGY; HUMAN; HYPOSPADIAS; INFANT; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; MALE; MATERNAL MORBIDITY; NEWBORN CARE; PLACENTA INSUFFICIENCY; PLACENTA WEIGHT; PRIORITY JOURNAL;

CASE-CONTROL STUDIES; FEMALE; FETAL GROWTH RETARDATION; FOLLOW-UP STUDIES; GESTATIONAL AGE; HUMANS; HYPOSPADIAS; INFANT, NEWBORN; INFANT, VERY LOW BIRTH WEIGHT; MALE; PLACENTAL INSUFFICIENCY; PREGNANCY; PREVALENCE; PROBABILITY; REFERENCE VALUES; RETROSPECTIVE STUDIES; RISK ASSESSMENT; TREATMENT OUTCOME; ULTRASONOGRAPHY, PRENATAL; UROLOGIC SURGICAL PROCEDURES, MALE;

EID: 38949083201     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2007.10.046     Document Type: Article

References (18)

1. Paulozzi L.J. International trends in rates of hypospadias and cryptorchism. Environ Health Perspect 107 (1999) 297-302
2. Baskin L.S., Colborn T., and Himes K. Hypospadias and endocrine disruption: is there a connection?. Environ Health Perspect 109 (2001) 1175-1183
3. Nelson C.P., Park J.M., Wan J., et al. The increasing incidence of congenital penile anomalies in the United States. J Urol 174 (2005) 1573-1576
4. Hussain N., Chaghtai A., Herdon A., et al. Hypospadias and early gestation growth restriction in infants. Pediatrics 109 (2002) 473-478
5. Gatti J.M., Kirsch A.J., Troyer M.R., et al. Increased incidence of hypospadias in small-for-gestational age infants in a neonatal intensive-care unit. BJU Int 87 (2001) 548-550
6. Brouwers M.M., Feitz W.F., Roelofs L.A.J., et al. Risk factors for hypospadias. Eur J Pediatr (2006) 671-678
7. Kurzrock E.A., and Karpman E. Hypospadias: pathophysiology and etiologic theories. Ped Endocrinol Rev 1 (2004) 288-295
8. Thomas DFM. Hypospadiology: science and surgery. BJU Int 2003;93:470-3
9. Baskin L.S. Hypospadia. In: Baskin L. (Ed). Hypospadias and genital development (2004), Kluwer Academic/Plenum Publisher, New York 3-22
10. Key T.J., Bull D., Ansell P., et al. A case-control study of cryptorchism and maternal hormone concentration in early pregnancy. Br J Cancer 73 (1996) 698-701
11. Kallen B. Case control study of hypospadias, based on registry information. Teratology 38 (1998) 45-50
12. Hym G., and Kolon T.F. Endocrine evaluation of hypospadias. In: Baskin L. (Ed). Hypospadias and genital development (2004), Kluwer Academic/Plenum Publisher, New York 31-43
13. Fredell L., Lichtenstein P., Pedersen N.L., et al. Hypospadias is related to birth weight in discordant monozygotic twins. J Urol 16 (1998) 2197-2199
14. Bryan J., Peters M., Pritchard G., et al. A second case of intrauterine growth retardation and primary hypospadias associated with a trisomy 22 placenta but with biparental inheritance of chromosome 22 in the fetus. Prenat Diagn 22 (2002) 137-140
15. Stoll C., Alembik Y., Roth M.P., et al. Genetic and environmental factors in hypospadias. J Med Genet 27 (1990) 559-563
16. Boisen K.A., Chellakooty M., Schmidt I.M., et al. Hypospadias in a cohort of 1072 Danish newborn boys: prevalence and relationship to placental weight, anthropometrical measurement at birth and reproductive hormone levels at three months of age. J Clin Endocrinol Metab 90 (2005) 4041-4046
17. Villar J., and Belizan J.M. The timing factor in the pathophysiology of the intrauterine growth retardation syndrome. Obstet Gynecol Surv 37 (1982) 499-506
18. Osawa H., Hata T., Soma H., et al. Placental weigh, function and fetal weight. Perinatal Med (Tokyo) 33 (2003) 728-729