Airborne particle monitoring in clean room environments for stem cell cultures

Biotechnology Journal

Volumn 3, Issue 1, 2008, Pages 43-52

  Cobo, Fernando ^a   Crela, David ^b   Concha, Angel ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DE LAS NIEVES   (Spain)

^b Hucoa Erloss   (Spain)

Author keywords

Cell bank installations; Clean rooms; Environmental monitoring; Particle counter; Particle measuring system

Indexed keywords

AIRBORNE PARTICLE MONITORING; ENVIRONMENTAL MONITORING;

CELL CULTURE; CLEAN ROOMS; CONTAMINATION; ENVIRONMENTAL REGULATIONS; HEALTH CARE;

PARTICLES (PARTICULATE MATTER);

AIR MONITORING; AIR QUALITY; AIR SAMPLING; AIRBORNE PARTICLE; AIRFLOW; CALIBRATION; CASCADE IMPACTOR; CERTIFICATION; COMPUTER PROGRAM; COMPUTER SYSTEM; CYCLONE SEPARATOR; DATA COLLECTION METHOD; DEVICE; FILTRATION; FLOW KINETICS; HEALTH CARE FACILITY; IMPACTION COUNTER; LASER PARTICLE COUNTER; LIGHT SCATTERING; MICROCOMPUTER; OPTICAL PARTICLE COUNTER; PARTICLE SIZE; PRIORITY JOURNAL; REVIEW; STEM CELL; STEM CELL BANK; VIRTUAL DICHOTOMOUS IMPACTOR;

AIR POLLUTANTS; ANIMALS; ENVIRONMENT, CONTROLLED; ENVIRONMENTAL MONITORING; HUMANS; PARTICULATE MATTER; STEM CELLS;

EID: 38849202449     PISSN: 18606768     EISSN: None     Source Type: Journal    
DOI: 10.1002/biot.200700122     Document Type: Review

References (27)

1. White, W., Bailey, P. V., Reduction of microbial dispersion by clothing. J. Parenter. Sci. Technol. 1985, 39, 51-61.
2. Backhouse, C. M., Ball, P. R., Booth, S., Kelshaw M. A. et al., Particulate contaminants of intravenous medications and infusions. J. Pharm. Pharmacol. 1987, 39, 241-245.
3. Wilson, R. D., Huang, S. J., McLean, A. S., The correlation between airborne methicilin resistant Staphylococcus aureus with the presence of MRSA colonized patients in a general intensive care unit. Anaesth. Intensive Care 2004, 32, 202-209.
4. Akers, M. J., Current problems and innovations in intravenous drug delivery. Am. J. Hosp. Pharm. 1987, 44, 2528-2532.
5. Tiwary, A., Colls, J. J., Measurements of atmospheric aerosol size distributions by co-located optical particle counters. J. Environ. Monit. 2004, 6, 734-739.
6. Miller, S. L., Nazaroff, W. W., Environmental tobacco smoke particles in multizone indoor environments. Atmos. Environ. 2001, 35, 2053-2067.
7. Lunden, M. M., Thatcher, T. L., Hering, S. V., Brown, N. J., Use of time and chemically resolved particulate data to characterize the infiltration of outdoor PM2. 5 into a residence in the San Joaquin Valley. Environ. Sci. Technol. 2003, 37, 4724-4732.
8. Veranth, J. M., Pardyjak, E. R., Seshadri, G., Vehicle-generated fugitive dust transport: Analytic models and field study. Atmos. Environ. 2003, 37, 2295-2303.
9. Hand, J. L., Kreidenweis, S. M., Kreisberg, N. et al., Comparisons of aerosol properties measured by impactors and light scattering from individual particles: Refractive index, number and volume concentrations, and size distributions. Atmos. Environ. 2002, 36, 1853-1861.
10. de Leeuw, G., Cohen, L., Frohn, L. M. et al., Atmospheric input of nitrogen into the North Sea: ANICE project overview. Cont. Shelf. Res. 2001, 21, 2073-2094.
11. Watson, I. M., Oppenheimer, C., Photometric observations of Mt. Etna's different aerosol plumes. Atmos. Environ. 2001, 35, 3561-3572.
12. May, K. R., The cascade impactor, an instrument for sampling coarse aerosol. Sci. Instrum. J. 1945, 22, 187-195.
13. International Standards Organization, ISO-14644-3, Clean Rooms and Associated Controlled Environments. Part 3: Metrology and Test Methods. International Organization for Standardization, Geneva, 2002.
14. Bénesse, M., Le Coq, L., Solliec, C., Collection efficiency of a woven filter made of multifiber yarn: Experimental characterization during loading and clean filter modeling bared on a two-tier single fiber approach. J. Aerosol Sci. 2006, 37, 974-989.
15. Coriell, L. L., MacGarrity, G. J., Concerning HEPA filtering. Am. J. Public Health 1971, 61, 1749-1750.
16. UNE-EN 1822-1, High Efficiency Air Filters (HEPLA and ULPA). Part 1: Classification, Performance Testing, Marking, 1998.
17. ASHRAE Standard 52.2, Method of Testing General Ventilation Air Cleaning Devices for Removal by Particle Size, 1999.
18. International Standards Organization, ISO-14644-1, Clean Rooms and Associated Controlled Environments. Part 1: Classification of Air Cleanliness. International Organization for Standardization, 1999.
19. Cobo, F., Stacey, G. N., Cortés, J. L., Concha, A., Enviromnental monitoring in stem cell banks. Appl. Microbiol. Biotechnol. 2006, 70, 651-662.
20. McFarland, A. R., Bethel, F. L., Ortiz, C. A., Stanke, J. G., A CAM (continuous air monitor) sampler for collecting and assessing alpha-emitting aerosol particles. Health Phys. 1991, 61, 97-103.
21. Johnston, M. V., Sampling and analysis of individual particles by aerosol mass spectrometry. J. Mass. Spectrom. 2000, 35, 585-595.
22. Dharan, S., Pittet, D., Environmental controls in operating theatres. J. Hosp. Infect. 2002, 51, 79-84.
23. U. K. Department of Health, A Code of Practice for Tissue Banks - Providing Tissues of Human Origin for Therapeutic Purposes. Department of Health. London 2001.
24. U. K. Department of Health, A Code of Practice for the Production of Human Derived Therapeutic Products. Department of Health, Medical Devices Agency, London 2002.
25. European Union Directive 23/CE. Relating to the Establishment of Quality and Safety Norms to Donate, to Obtain, to Assess, to Process, to Preserve, to Store and to Distribute Cells and Human Tissues. Brussels 2004.
26. U. S. Food and Drug Administration, Guidance for Human Cells, Tissues, and Cellular and Tissue-Based Products. Rockville 2005.
27. Good Tissue Practice. Validation of Procedures for Processing of Human Tissues Intended for Transplantation. Rockville 2004.