Efficacy and tolerability of topical tacrolimus in the treatment of atopic dermatitis: A systematic review of randomized controlled trials

Journal of Clinical Dermatology

Volumn 36, Issue 12, 2007, Pages 757-760

  Li, Run Xiang ^a   Zhu, Hui Lan ^a   Fan, Li Ming ^a   Ni, Shao Kai ^a   Feng, Cheng En ^a   Wu, Zhi Hua ^a  

^a GUANGZHOU INSTITUTE OF DERMATOLOGY   (China)

Author keywords

Dermatitis, atopic; Hydrocortisone; Randomized controlled trials; Tacrolimus

Indexed keywords

HYDROCORTISONE ACETATE; HYDROCORTISONE BUTYRATE; PLACEBO; TACROLIMUS;

ATOPIC DERMATITIS; BURNING SENSATION; CLINICAL TRIAL; COCHRANE LIBRARY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG TOLERABILITY; HUMAN; MEDLINE; RANDOMIZED CONTROLLED TRIAL; REVIEW; SKIN IRRITATION; SYSTEMATIC REVIEW;

EID: 38849202417     PISSN: 10004963     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (16)

1. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis[J]. Acta Derm Venereol (Stockh), 1980, (Suppl 92): 44.
2. Chinese source.
3. Boguniewicz M, Fiedler VC, Raimer S, et al. A randomized, vehicle-controlled trial of tacrolimus ointment for treatment of atopic dermatitis in children. Pediatric Tacrolimus Study Group [J]. J Allergy Clin Immunol, 1998, 102(4 Pt 1): 637-644.
4. Reitamo S, Van Leent EJ, Ho V, et al. Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone acetate ointment in children with atopic dermatitis [J]. J Allergy Clin Immunol, 2002, 109(3): 539-546.
5. Reitamo S, Rustin M, Ruzicka T, et al. Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone butyrate ointment in adult patients with atopic dermatitis[J]. J Allergy Clin Immunol, 2002, 109(3): 547-555.
6. Ruzicka T, Bieber T, Schopf E, et al. A short-term trial of tacrolimus ointment for atopic dermatitis. European Tacrolimus Multicenter Atopie Dermatitis Study Group [J]. N Engl J Med, 1997, 337(12): 816-821.
7. Paller A, Eichenfield LF, Leung DY, et al. A 12-week study of tacrolimus ointment for the treatment of atopic dermatitis in pediatric patients[J]. J Am Acad Dermatol, 2001, 44(1 Suppl): S47-57.
8. H Hanifin JM, Ling MR, Langley R, et al. Tacrolimus ointment for the treatment of atopic dermatitis in adult patients: part I, efficacy[J]. J Am Acad Dermatol, 2001, 44(1 Suppl): S28-38.
9. Soter NA, Fleischer AB, Webster GF, et al. Tacrolimus ointment for the treatment of atopic dermatitis in adult patients: part II, safety[J]. J Am Acad Dermatol, 2001, 44(1 Suppl): S39-46.
10. Drake L, Prendergast M, Maher R, et al. The impact of tacrolimus ointment on health-related quality of life of adult and pediatric patients with atopic dermatitis[J]. J Am Acad Dermatol, 2001, 44(1 Suppl): S65-72.
11. Reitamo S, Harper J, Bos JD, et al. 0.03% Tacrolimus ointment applied once or twice daily is more efficacious than 1% hydrocortisone acetate in children with moderate to severe atopic dermatitis: results of a randomized double-blind controlled trial[J]. Br J Dermatol, 2004, 150(3): 554-562.
12. Reitamo S, Ortonne JP, Sand C, et al. A multicentre, randomized, double-blind, controlled study of long-term treatment with 0.1% tacrolimus ointment in adults with moderate to severe atopic dermatitis[J]. Br J Dermatol, 2005, 152(6): 1282-1289.
13. Schachner LA, Lamerson C, Sheehan MP, et al. Tacrolimus ointment 0.03% is safe and effective for the treatment of mild to moderate atopic dermatitis in pediatric patients: results from a randomized, double-blind, vehicle-controlled study[J]. Pediatrics, 2005, 116(3): e334-e342.
14. Chinese source.
15. Hjelmgren J, Svensson A, Jorgensen ET, et al. Cost-effectiveness of tacrolimus ointment vs. standard treatment in patients with moderate and severe atopic dermatitis: a health-economic model simulation based on a patient survey and clinical trial data [J]. Br J Dermatol, 2007, 156(5): 913-921.
16. Naylor M, Elmets C, Jaracz E, et al. Non-melanoma skin cancer in patients with atopic dermatitis treated with topical tacrolimus [J]. J Dermatolog Treat, 2005, 16(3): 149-153.