Total synthesis of (+)- and (-)-duryne: A potent anticancer agent from the marine sponge cribrochalina dura. Establishment of the central double bond geometry and the absolute configuration of the chiral centers

Journal of Organic Chemistry

Volumn 73, Issue 3, 2008, Pages 1067-1070

  Gung, Benjamin W ^a   Omollo, Ann O ^a  

^a MIAMI UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICANCER AGENTS; CHIRAL CENTERS; POLYACETYLENIC ALCOHOLS;

ALCOHOLS; BIOSYNTHESIS; CHIRALITY; CYTOTOXICITY; GEOMETRY; ISOMERS; REACTION KINETICS;

POLYACETYLENES;

ALKENE; ANTINEOPLASTIC AGENT; DURYNE; LITHIUM DERIVATIVE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CHIRALITY; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; PSEUDOMONAS; REDUCTION; SPONGE (PORIFERA); STEREOCHEMISTRY; WITTIG REACTION;

ACETYLENE; ALCOHOLS; ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL PRODUCTS; MOLECULAR CONFORMATION; OCEANS AND SEAS; PORIFERA; STEREOISOMERISM;

EID: 38849190696     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo702399j     Document Type: Article

References (19)

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