Direct hemoperfusion with a cytokine-adsorbing device for the treatment of persistent or severe hypercytokinemia: A pilot study

Blood Purification

Volumn 25, Issue 5-6, 2008, Pages 446-453

  Kobe, Y ^a   Oda, S ^a   Matsuda, K ^b   Nakamura, M ^a   Hirasawa, H ^a  

^a CHIBA UNIVERSITY   (Japan)

^b YAMANASHI PREFECTURAL CENTRAL HOSPITAL   (Japan)

Author keywords

Cytokine adsorbing device; Hypercytokinemia; Rapid cytokine assay

Indexed keywords

CYTOKINE;

ADULT; AGED; ARTERIAL OXYGEN TENSION; ARTICLE; CLINICAL ARTICLE; CRITICALLY ILL PATIENT; CYTOKINE PRODUCTION; DEVICE; DISEASE SEVERITY; FEMALE; HEMOPERFUSION; HUMAN; HYPERCYTOKINEMIA; IMMUNOPATHOLOGY; MALE; PRIORITY JOURNAL; SCORING SYSTEM; SURVIVAL RATE; SURVIVAL TIME; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE;

AGED; AGED, 80 AND OVER; CRITICAL ILLNESS; CYTOKINES; EQUIPMENT DESIGN; FEMALE; HEMOPERFUSION; HUMANS; MALE; MIDDLE AGED; OXYGEN; PARTIAL PRESSURE; PILOT PROJECTS; SURVIVAL RATE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TREATMENT OUTCOME;

EID: 38849176992     PISSN: 02535068     EISSN: None     Source Type: Journal    
DOI: 10.1159/000111568     Document Type: Article

References (20)

1. Balk RA: Pathogenesis and management of multiple organ dysfunction of failure in severe sepsis and septic shock. Crit Care Clin 2000;16:337-352.
2. Spittler A, Razenberger M, Kupper H, Kaul M, Hackl W, Boltz-Nitulescu G, Fugger R, Roth E: Relationship between interleukin-6 plasma concentration in patients with sepsis, monocyte phenotype, monocyte phagocytic properties, and cytokine production. Clin Infect Dis 2000;31:1338-1342.
3. Adrie C, Pinsky MR: The inflammatory balance in human sepsis. Intensive Care Med 2000;26:364-375.
4. Oda S, Hirasawa H, Shiga H, Nakanishi K, Matsuda K, Nakamura M: Continuous hemofiltration/hemodiafiltration in critical care. Ther Apher 2002;6:193-198.
5. Kellum JA, Venkataraman R: Blood purification in sepsis: an idea whose time has come? Crit Care Med 2002;30:1387-1388.
6. Matsuda K, Hirasawa H, Oda S, Shiga H, Nakanishi K: Current topics on cytokine removal technologies. Ther Apher 2001;5:306-314.
7. Hirasawa H, Oda S, Shiga H, Matuda K: Endotoxin adsorption or hemodiafiltration in the treatment of multiple organ failure. Curr Opin Crit Care 2000;6:421-425.
8. Miwa K, Fukuyama M, Ida N, Igarashi H, Uchiyama T: Preparation of a superantigen-adsorbing device and its superantigen removal efficacies in vitro and in vivo. Int J Infect Dis 2003;7:21-26.
9. Miwa K, Shibayama N, Ida N, Kawabe Y, Ohzeki T: A novel blood purification therapy for the treatment of Gram-positive bacterial sepsis. Jpn J Apher 2005;24:244-249.
10. Shoji H: Extracorporeal endotoxin removal for the treatment of sepsis: endotoxin adsorption cartridge (Toraymyxin). Ther Apher 2003;7:108-114.
11. Rossi CL, Tsang VC, Pilcher JB: Rapid, lowtechnology field- and laboratory-applicable enzyme-linked immunosorbent assays for immunodiagnosis of Schistosoma mansoni. J Clin Microbiol 1991;29:1836-1841.
12. Vincent JL, Laterre PF, Cohen J, Burchardi H, Bruining H, Lerma FA, Wittebole X, De Backer D, Brett S, Marzo D, Nakamura H, John S: A pilot-controlled study of a polymyxin B-immobilized hemoperfusion cartridge in patients with severe sepsis secondary to intra-abdominal infection. Shock 2005;23:400-405.
13. Fenwick P, Ryan C, Sriskandan S, Cohen J: Application of a rat model of streptococcal shock to evaluate on-line hemoperfusion and removal of circulating superantigens. Crit Care Med 2003;31:171-178.
14. Miwa K, Fukuyama M, Matsuno N, Shimada K, Ikeda K, Ikeda T: Physiological response to superantigen-adsorbing hemoperfusion in toxin-concentration- controlled septic swine. Blood Purif 2006;24:319-326.
15. Winchester JF, Kellum JA, Ronco C, Brady JA, Quartararo PJ, Salsberg JA, Levin NW: Sorbents in acute renal failure and the systemic inflammatory response syndrome. Blood Purif 2003;21:79-84.
16. Kellum JA, Song M, Vankataraman P: Hemoadsorption removes tumor necrosis factor, interleukin-6, and interleukin-10, reduces nuclear factor-κB DNA binding, and improves short-term survival in lethal endotoxemia. Crit Care Med 2004;32:801-805.
17. Taniguchi T, Hirai F, Takemoto Y, Tsuda K, Yamamoto K, Inaba H, Sakurai H, Furuyoshi S, Tani N: A novel adsorbent of circulating bacterial toxins and cytokines. Crit Care Med 2006;34:800-806.
18. Saotome T, Endo Y, Sasaki T, Tabata T, Hamamoto T, Fujino K, Andoh A, Eguchi Y, Tani T, Fujiyama Y: A case of severe acute pancreatitis treated with CTR-001 direct hemoperfusion for cytokine apheresis. Ther Apher Dial 2005;9:367-371.
19. Oda S, Hirasawa H, Matsuda K, Nakanishi K, Matsuda K, Nakamura M, Ikeda H, Sakai M: Cytokine adsorptive property of various adsorbents in immunoadsorption columns and a newly developed adsorbent. Blood Purif 2004;22:530-536.
20. Watanabe E, Hirasawa H, Oda S, Matsuda K, Hatano M, Tokuhisa T: Extremely high interleukin-6 blood levels and outcome in the critically ill are associated with tumor necrosis factor- and interleukin-1-related gene polymorphisms. Crit Care Med 2005;33:89-97.