Disseminated necrotizing leukoencephalopathy following chemoradiation therapy for acute lymphoblastic leukemia

Radiation Medicine - Medical Imaging and Radiation Oncology

Volumn 24, Issue 7, 2006, Pages 515-519

  Pande, Ajaya R ^a   Ando, Kumiko ^a   Ishikura, Reiichi ^a   Nagami, Yuki ^a   Ogawa, Masayo ^a   Kamikonya, Norihiko ^a   Kaneda, Yumi ^a   Tanizawa, Takakuni ^a   Nakao, Norio ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

ALL; Leukoencephalopathy; Methotrexate; MRI; Radiotherapy

Indexed keywords

CONTRAST MEDIUM; METHOTREXATE; ANTINEOPLASTIC ANTIMETABOLITE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; BRAIN DAMAGE; CANCER RADIOTHERAPY; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DISEASE COURSE; DRUG MEGADOSE; FEMALE; FOLLOW UP; HUMAN; LEUKOENCEPHALOPATHY; LONG TERM CARE; NECROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRESCHOOL CHILD; RADIATION DOSE; WHITE MATTER; ACUTE LYMPHOCYTIC LEUKEMIA; BRAIN; BRAIN DISEASE; MULTIMODALITY CANCER THERAPY; PATHOLOGY; RADIOGRAPHY; SKULL IRRADIATION;

ANTIMETABOLITES, ANTINEOPLASTIC; BRAIN; BRAIN DISEASES; CHILD, PRESCHOOL; COMBINED MODALITY THERAPY; CRANIAL IRRADIATION; FEMALE; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; MAGNETIC RESONANCE IMAGING; METHOTREXATE; NECROSIS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 38849162365     PISSN: 02882043     EISSN: 18625274     Source Type: Journal    
DOI: 10.1007/s11604-006-0059-5     Document Type: Article

References (16)

1. S Berg DG Poplack 1995 Clinical manifestations of acute lymphocytic leukemia in children R Hoffman EJ Benz SJ Shattil B Furie HJ Cohen LE Silberstein Hematology, basic principles and practice 2nd edition Churchill Livingstone New York 1067 74
2. SE Sallan HJ Cohen 1995 Therapy for acute lymphocytic leukemia in children R Hoffman EJ Benz SJ Shattil B Furie HJ Cohen LE Silberstein Hematology, basic principles and practice 2nd edition Churchill Livingstone New York 1075 84
3. K Suzuki T Takemura R Okeda S Hatakeyama 1984 Vascular changes of methotrexate-related disseminated necrotizing leukoencephalopathy Acta Neuropathol (Berl) 65 145 9
4. LJ Rubinstein MM Herman TF Long JR Wilbur 1975 Disseminated necrotizing leukoencephalopathy: a complication of treated central nervous system leukemia and lymphoma Cancer 35 291 305
5. WA Bleyer RL Dedrich 1977 Clinical pharmacology of intrathecal methotrexate. II. An improved dosage regimen derived from age related pharmacokinetics Cancer Treat Rep 61 1419 25
6. H Sakamaki Y Onozawa Y Yano K Imai T Sasaki T Ibuka 1993 Disseminated necrotizing leukoencephalopathy following irradiation and methotrexate therapy for central nervous system infiltration of leukemia and lymphoma Radiat Med 11 146 53
7. SN Laxmi S Takahashi K Matsumoto S Higano N Kurihara M Imaizumi 1996 Treatment related disseminated necrotizing leukoencephalopathy with characteristic contrast enhancement of the white matter Radiat Med 14 303 7
8. T Shimura S Nakazawa Y Akutsu M Matsumoto M Kazuhara D Yoshida 1989 Disseminated necrotizing leukoencephalopathy accompanied with multiple calcium deposits following antineoplastic and radiation therapy in a case of intracranial germ cell tumor: computerized tomographical study No Shinkei Geka 17 573 7
9. Y Ohmoto K Kajiwara S Kato T Nisizaki H Ito S Tamura 1996 Atypical MRI findings in treatment related leucoencephalopathy Neuroradiology 38 128 33
10. DA Wilson R Nitschke ME Bowman MJ Chaffin CL Sexauer JR Prince 1991 Transient white matter changes on MR images in children undergoing chemotherapy for acute lymphoblastic leukemia Radiology 180 205 9
11. M Oka S Terae R Kobayashi Y Sawamura K Kudoh KK Tha 2003 MRI in methotrexate-related leukoencephalopathy: disseminated necrotizing leukoencephalopathy in comparison with mild leukoencephalopathy Neuroradiology 45 493 7
12. Y Asada S Kohga A Sumiyoshi M Ishikawa H Nakamura 1988 Disseminated necrotizing encephalopathy induced by methotrexate therapy alone Acta Pathol 38 1305 12
13. ME Haykin M Gorman J van Hoff RK Fulbright JM Baehring 2006 Diffusion weighted MRI correlates of subacute methotrexate-related neurotoxicity J Neurooncol 76 153 7
14. W Kuker P Bader U Herrlinger S Heckl T Nagele 2005 Transient encephalopathy after intrathecal methotrexate chemotherapy: diffusion weighted MRI J Neurooncol 73 47 9
15. K Lovblad P Kelkar C Ozdoba G Ramelli L Remonda G Schroth 1998 Pure methotrexate encephalopathy presenting with seizures: CT and MRI features Pediatr Radiol 28 86 91
16. K Muller R Menne K Bachmann H Grobe 1981 Calcified cerebral necrosis following ALL therapy J Cancer Res Clin Oncol 102 81 91