A case report of plasmapheresis treatment in a patient with paraneoplastic cerebellar degeneration and high anti-Yo antibody titers

Therapeutic Apheresis and Dialysis

Volumn 12, Issue 1, 2008, Pages 82-85

  Landtblom, Anne Marie ^a,c   Lindvall, Björn ^b   Ledin, Torbjörn ^a   Berlin, Gösta ^a  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^b ÖREBRO UNIVERSITY HOSPITAL   (Sweden)

^c NONE   (Sweden)

Author keywords

Anti Yo antibody; Central nervous system; Cerebellum; Paraneoplastic; Plasmapheresis

Indexed keywords

ANTINEOPLASTIC AGENT; CELL ANTIBODY;

ADULT; ANAMNESIS; ANTIBODY TITER; ARTICLE; BLOOD SAMPLING; CALORIC INTAKE; CANCER CHEMOTHERAPY; CANCER GROWTH; CASE REPORT; CLINICAL FEATURE; DISEASE COURSE; DISEASE EXACERBATION; DYSARTHRIA; DYSMETRIA; FEMALE; HUMAN; LABORATORY TEST; NYSTAGMUS; OVARY CARCINOMA; PARANEOPLASTIC NEUROPATHY; PATIENT MONITORING; PLASMAPHERESIS; PRIORITY JOURNAL; SEROLOGY; UNSPECIFIED SIDE EFFECT; VESTIBULOOCULAR REFLEX;

AUTOANTIBODIES; FEMALE; HUMANS; MIDDLE AGED; NEOPLASM METASTASIS; OVARIAN NEOPLASMS; PARANEOPLASTIC CEREBELLAR DEGENERATION; PLASMAPHERESIS; PURKINJE CELLS;

EID: 38849152155     PISSN: 17449979     EISSN: 17449987     Source Type: Journal    
DOI: 10.1111/j.1744-9987.2007.00546.x     Document Type: Article

References (12)

1. Jaeckle KA, Graus F, Houghton A, Cardon-Cardo C, Nielsen SL, Posner JB. Autoimmune response of patients with paraneoplastic cerebellar degeneration to a Purkinje cell cytoplasmic protein antigen. Ann Neurol 1985 18 : 592.
2. Peterson K, Rosenblum MK, Kotanides H, Posner JB. Paraneoplastic cerebellar degeneration. Neurology 1992 42 : 1931 7.
3. Shams'ili S, Grefkens J, de Leeuw BD et al. Paraneoplastic cerebellar degeneration associated with the antineuronal antibodies: analysis of 50 patients. Brain 2003 126 : 1409 18.
4. Dalmau J, Posner JB. Neurologic paraneoplastic antibodies (anti-Yo; anti-Hu; anti-Ri): the case for a nomenclature based on antibody and antigen specificity. Neurology 1994 44 : 22421 246.
5. Peltola J, Hietaharju A, Rantala I, Lehtinen T, Haapasalo H. A reversible neuronal antibody (anti-Tr) associated paraneoplastic cerebellar degeneration in Hodgkin's disease. Acta Neurol Scand 1998 98 : 360 3.
6. Bernal F, Shams'ili S, Rojas I et al. Anti-Tr antibodies as markers of paraneoplastic cerebellar degeneration and Hodgkin's disease. Neurology 2003 60 : 230 4.
7. Anderson NE, Cunningham JM, Posner JB. Autoimmune pathogenesis of paraneoplastic neurological syndromes. Crit Rev Neurobiology 1987 3 : 245 54.
8. David YB, Warner E, Levitan M, Sutton DM, Malkin MG, Dalmau JO. Autoimmune paraneoplastic cerebellar degeneration in ovarian carcinoma patients treated with plasmapheresis and immunoglobulin. A case report. Cancer 1996 15 : 2153 6.
9. Spyridonidis A, Fischer KG, Glocker FX, Fetscher S, Klisch J, Behringer D. Paraneoplastic cerebellar degeneration and nephrotic syndrome preceding Hodgkin's disease: case report and review of the literature. Eur J Haematol 2002 68 : 318 21.
10. Taniguchi Y, Tanji C, Kawai T, Saito H, Marubayashi S, Yorioka N. A case report of plasmapheresis in paraneoplastic cerebellar ataxia associated with anti-Tr antibody. Ther Apher Dial 2006 10 : 90 3.
11. Santillan A, Bristow RE. Paraneoplastic cerebellar degeneration in a woman with ovarian cancer. Nat Clin Pract Oncol 2006 3 : 108 12.
12. Furneaux HF, Reich L, Posner JB. Autoantibody synthesis in the central nervous system of patients with paraneoplastic syndromes. Neurology 1990 7 : 1085 91.