Decreased biliary excretion of tributylmethyl ammonium in cholestyramine pretreated rats due to reduced formation of ion-pair complexes with hepatic bile salts

Biopharmaceutics and Drug Disposition

Volumn 28, Issue 9, 2007, Pages 485-490

  Choi, M K ^a   Song, I S ^b   Kim, D D ^a   Chung, S J ^a   Shim, C K ^a  

^a Seoul National University   (South Korea)

^b Inje University College of Medicine   (South Korea)

Author keywords

Biliary excretion; Cholestyramine; Ion pair complexes; Quaternary ammoniums (QAs); TBuMA

Indexed keywords

BILE SALT; COLESTYRAMINE; GLYCOPROTEIN P; QUATERNARY AMMONIUM DERIVATIVE; TRIBUTYLMETHYLAMMONIUM;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BILE FLOW; BILIARY EXCRETION; COMPLEX FORMATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; LIVER; MALE; MEAN RESIDENCE TIME; MOLECULAR WEIGHT; NONHUMAN; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ANION EXCHANGE RESINS; AREA UNDER CURVE; BILE; BILE ACIDS AND SALTS; BIOLOGICAL TRANSPORT, ACTIVE; CHOLESTYRAMINE; INJECTIONS, INTRAVENOUS; LIVER; P-GLYCOPROTEIN; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

EID: 38849151552     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.580     Document Type: Article

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