-
1
-
-
33646052947
-
Flavodoxins: Sequence, folding, binding, function and beyond
-
Sancho, J. (2006) Flavodoxins: sequence, folding, binding, function and beyond, Cell Mol. Life Sci. 63, 855-864.
-
(2006)
Cell Mol. Life Sci. 63
, pp. 855-864
-
-
Sancho, J.1
-
2
-
-
8744301024
-
The long and short flavodoxins: I. The role of the differentiating loop in apoflavodoxin structure and FMN binding
-
Lopez-Llano, J., Maldonado, S., Bueno, M., Lostao, A., Angeles-Jimenez, M., Lillo, M. P., and Sancho, J. (2004) The long and short flavodoxins: I. The role of the differentiating loop in apoflavodoxin structure and FMN binding, J. Biol. Chem. 279, 47177-47183.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 47177-47183
-
-
Lopez-Llano, J.1
Maldonado, S.2
Bueno, M.3
Lostao, A.4
Angeles-Jimenez, M.5
Lillo, M.P.6
Sancho, J.7
-
3
-
-
8744313991
-
The long and short flavodoxins: II. The role of the differentiating loop in apoflavodoxin stability and folding mechanism
-
Lopez-Llano, J., Maldonado, S., Jain, S., Lostao, A., Godoy-Ruiz, R., Sanchez-Ruiz, J. M., Cortijo, M., Fernandez-Recio, J., and Sancho, J. (2004) The long and short flavodoxins: II. The role of the differentiating loop in apoflavodoxin stability and folding mechanism, J. Biol. Chem. 279, 47184-47191.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 47184-47191
-
-
Lopez-Llano, J.1
Maldonado, S.2
Jain, S.3
Lostao, A.4
Godoy-Ruiz, R.5
Sanchez-Ruiz, J.M.6
Cortijo, M.7
Fernandez-Recio, J.8
Sancho, J.9
-
4
-
-
0027082206
-
Structure of the oxidized long-chain flavodoxin from Anabaena 7120 at 2 Å resolution
-
Rao, S. T., Shaffie, F., Yu, C., Satyshur, K. A., Stockman, B. J., Markley, J. L., and Sundarlingam, M. (1992) Structure of the oxidized long-chain flavodoxin from Anabaena 7120 at 2 Å resolution, Protein Sci. 1, 1413-1427.
-
(1992)
Protein Sci
, vol.1
, pp. 1413-1427
-
-
Rao, S.T.1
Shaffie, F.2
Yu, C.3
Satyshur, K.A.4
Stockman, B.J.5
Markley, J.L.6
Sundarlingam, M.7
-
5
-
-
0029989460
-
Closure of a tyrosine/tryptophan aromatic gate leads to a compact fold in apo flavodoxin
-
Genzor, C. G., Perales-Alcon, A., Sancho, J., and Romero, A. (1996) Closure of a tyrosine/tryptophan aromatic gate leads to a compact fold in apo flavodoxin, Nat. Struct. Biol. 3, 329-332.
-
(1996)
Nat. Struct. Biol
, vol.3
, pp. 329-332
-
-
Genzor, C.G.1
Perales-Alcon, A.2
Sancho, J.3
Romero, A.4
-
6
-
-
0029943149
-
Conformational stability of apoflavodoxin
-
Genzor, C. G., Beldarrain, A., Gomez-Moreno, C., Lopez-Lacomba, J. L., Cortijo, M., and Sancho, J. (1996) Conformational stability of apoflavodoxin, Protein Sci. 5, 1376-1388.
-
(1996)
Protein Sci
, vol.5
, pp. 1376-1388
-
-
Genzor, C.G.1
Beldarrain, A.2
Gomez-Moreno, C.3
Lopez-Lacomba, J.L.4
Cortijo, M.5
Sancho, J.6
-
7
-
-
0034737647
-
Dissecting the energetics of the apoflavodoxin-FMN complex
-
Lostao, A., El Harrous, M., Daoudi, F., Romero, A., Parody-Morreale, A., and Sancho, J. (2000) Dissecting the energetics of the apoflavodoxin-FMN complex, J. Biol. Chem. 275, 9518-9526.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 9518-9526
-
-
Lostao, A.1
El Harrous, M.2
Daoudi, F.3
Romero, A.4
Parody-Morreale, A.5
Sancho, J.6
-
8
-
-
0037929808
-
How FMN binds to Anabaena apoflavodoxin: A hydrophobic encounter at an open binding site
-
Lostao, A., Daoudi, F., Irun, M. P., Ramon, A., Fernandez-Cabrera, C., Romero, A., and Sancho, J. (2003) How FMN binds to Anabaena apoflavodoxin: a hydrophobic encounter at an open binding site, J. Biol. Chem. 278, 24053-24061.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 24053-24061
-
-
Lostao, A.1
Daoudi, F.2
Irun, M.P.3
Ramon, A.4
Fernandez-Cabrera, C.5
Romero, A.6
Sancho, J.7
-
9
-
-
33646052300
-
Native-specific stabilization of flavodoxin by the FMN cofactor: Structural and thermodynamical explanation
-
Campos, L. A., and Sancho, J. (2006) Native-specific stabilization of flavodoxin by the FMN cofactor: structural and thermodynamical explanation, Proteins 63, 581-594.
-
(2006)
Proteins
, vol.63
, pp. 581-594
-
-
Campos, L.A.1
Sancho, J.2
-
10
-
-
0031792027
-
The equilibrium unfolding of Azotobacter vinelandii apoflavodoxin II occurs via a relatively stable folding intermediate
-
van Mierlo, C. P., van Dongen, W. M., Vergeldt, F., van Berkel, W. J., and Steensma, E. (1998) The equilibrium unfolding of Azotobacter vinelandii apoflavodoxin II occurs via a relatively stable folding intermediate, Protein Sci. 7, 2331-2344.
-
(1998)
Protein Sci
, vol.7
, pp. 2331-2344
-
-
van Mierlo, C.P.1
van Dongen, W.M.2
Vergeldt, F.3
van Berkel, W.J.4
Steensma, E.5
-
11
-
-
14844322304
-
Last in, first out: The role of cofactor binding in flavodoxin folding
-
Bollen, Y. J., Nabuurs, S. M., van Berkel, W. J., and van Mierlo, C. P. (2005) Last in, first out: the role of cofactor binding in flavodoxin folding, J. Biol. Chem. 280, 7836-7844.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 7836-7844
-
-
Bollen, Y.J.1
Nabuurs, S.M.2
van Berkel, W.J.3
van Mierlo, C.P.4
-
12
-
-
4944267705
-
Thermal unfolding of Apo and Holo Desulfovibrio desulfuricans flavodoxin: Cofactor stabilizes folded and intermediate states
-
Muralidhara, B. K., and Wittung-Stafshede, P. (2004) Thermal unfolding of Apo and Holo Desulfovibrio desulfuricans flavodoxin: cofactor stabilizes folded and intermediate states, Biochemistry 43, 12855-12864.
-
(2004)
Biochemistry
, vol.43
, pp. 12855-12864
-
-
Muralidhara, B.K.1
Wittung-Stafshede, P.2
-
13
-
-
0036156208
-
A comparison of the urea-induced unfolding of apoflavodoxin and flavodoxin from Desulfovibrio vulgaris
-
Nuallain, B. O., and Mayhew, S. G. (2002) A comparison of the urea-induced unfolding of apoflavodoxin and flavodoxin from Desulfovibrio vulgaris, Eur. J. Biochem. 269, 212-223.
-
(2002)
Eur. J. Biochem
, vol.269
, pp. 212-223
-
-
Nuallain, B.O.1
Mayhew, S.G.2
-
14
-
-
0026560942
-
Hypotheses on the pathogenesis and natural history of Helicobacter pylori-induced inflammation
-
Blaser, M. J. (1992) Hypotheses on the pathogenesis and natural history of Helicobacter pylori-induced inflammation, Gastroenterology 102, 720-727.
-
(1992)
Gastroenterology
, vol.102
, pp. 720-727
-
-
Blaser, M.J.1
-
15
-
-
0025945933
-
Helicobacter pylori infection and the risk of gastric carcinoma
-
Parsonnet, J., Friedman, G. D., Vandersteen, D. P., Chang, Y., Vogelman, J. H., Orentreich, N., and Sibley, R. K. (1991) Helicobacter pylori infection and the risk of gastric carcinoma, N. Engl. J. Med. 325, 1127-1131.
-
(1991)
N. Engl. J. Med
, vol.325
, pp. 1127-1131
-
-
Parsonnet, J.1
Friedman, G.D.2
Vandersteen, D.P.3
Chang, Y.4
Vogelman, J.H.5
Orentreich, N.6
Sibley, R.K.7
-
16
-
-
0027213922
-
Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori
-
Wotherspoon, A. C., Doglioni, C., Diss, T. C., Pan, L., Moschini, A., de Boni, M., and Isaacson, P. G. (1993) Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori, Lancet 342, 575-577.
-
(1993)
Lancet
, vol.342
, pp. 575-577
-
-
Wotherspoon, A.C.1
Doglioni, C.2
Diss, T.C.3
Pan, L.4
Moschini, A.5
de Boni, M.6
Isaacson, P.G.7
-
17
-
-
0029119213
-
The incidence of Helicobacter pylori infection
-
Parsonnet, J. (1995) The incidence of Helicobacter pylori infection, Aliment. Pharmacol. Ther. 9 Suppl. 2, 45-51.
-
(1995)
Aliment. Pharmacol. Ther
, vol.9
, Issue.SUPPL. 2
, pp. 45-51
-
-
Parsonnet, J.1
-
18
-
-
0036145495
-
Crystal structure of oxidized flavodoxin, an essential protein in Helicobacter pylori
-
Freigang, J., Diederichs, K., Schafer, K. P., Welte, W., and Paul, R. (2002) Crystal structure of oxidized flavodoxin, an essential protein in Helicobacter pylori, Protein Sci. 11, 253-261.
-
(2002)
Protein Sci
, vol.11
, pp. 253-261
-
-
Freigang, J.1
Diederichs, K.2
Schafer, K.P.3
Welte, W.4
Paul, R.5
-
19
-
-
34347386473
-
Flavodoxin:Quinone Reductase (FqrB): A Redox Partner of Pyruvate:Ferredoxin Oxidoreductase That Reversibly Couples Pyruvate Oxidation to NADPH Production in Helicobacter pylori and Campylobacter jejuni
-
St Maurice, M., Cremades, N., Croxen, M. A., Sisson, G., Sancho, J., and Hoffman, P. S. (2007) Flavodoxin:Quinone Reductase (FqrB): a Redox Partner of Pyruvate:Ferredoxin Oxidoreductase That Reversibly Couples Pyruvate Oxidation to NADPH Production in Helicobacter pylori and Campylobacter jejuni, J. Bacteriol. 189, 4764-4773.
-
(2007)
J. Bacteriol. 189
, pp. 4764-4773
-
-
St Maurice, M.1
Cremades, N.2
Croxen, M.A.3
Sisson, G.4
Sancho, J.5
Hoffman, P.S.6
-
20
-
-
14744268574
-
Towards a new therapeutic target: Helicobacter pylori flavodoxin
-
Cremades, N., Bueno, M., Toja, M., and Sancho, J. (2005) Towards a new therapeutic target: Helicobacter pylori flavodoxin, Biophys. Chem. 115, 267-276.
-
(2005)
Biophys. Chem
, vol.115
, pp. 267-276
-
-
Cremades, N.1
Bueno, M.2
Toja, M.3
Sancho, J.4
-
21
-
-
35448929947
-
Common conformational changes in flavodoxins induced by FMN and anion binding: The structure of H. pylori apoflavodoxin
-
Martínez-Júlvez, M., Cremades, N., Bueno, M., Perez-Dorado, I., Maya, C., Cuesta-Lopez, S., Diego, P., Falo, F., Hermoso, J. A., and Sancho, J. (2007) Common conformational changes in flavodoxins induced by FMN and anion binding: the structure of H. pylori apoflavodoxin, Proteins 69, 581-594.
-
(2007)
Proteins
, vol.69
, pp. 581-594
-
-
Martínez-Júlvez, M.1
Cremades, N.2
Bueno, M.3
Perez-Dorado, I.4
Maya, C.5
Cuesta-Lopez, S.6
Diego, P.7
Falo, F.8
Hermoso, J.A.9
Sancho, J.10
-
22
-
-
18244380348
-
High-density miniaturized thermal shift assays as a general strategy for drug discovery
-
Pantoliano, M. W., Petrella, E. C., Kwasnoski, J. D., Lobanov, V. S., Myslik, J., Graf, E., Carver, T., Asel, E., Springer, B. A., Lane, P., and Salemme, F. R. (2001) High-density miniaturized thermal shift assays as a general strategy for drug discovery, J. Biomol. Screening 6, 429-440.
-
(2001)
J. Biomol. Screening
, vol.6
, pp. 429-440
-
-
Pantoliano, M.W.1
Petrella, E.C.2
Kwasnoski, J.D.3
Lobanov, V.S.4
Myslik, J.5
Graf, E.6
Carver, T.7
Asel, E.8
Springer, B.A.9
Lane, P.10
Salemme, F.R.11
-
23
-
-
7044231161
-
Structure of stable protein folding intermediates by equilibrium phi-analysis: The apoflavodoxin thermal intermediate
-
Campos, L. A., Bueno, M., Lopez-Llano, J., Jimenez, M. A., and Sancho, J. (2004) Structure of stable protein folding intermediates by equilibrium phi-analysis: the apoflavodoxin thermal intermediate, J. Mol. Biol. 344, 239-255.
-
(2004)
J. Mol. Biol
, vol.344
, pp. 239-255
-
-
Campos, L.A.1
Bueno, M.2
Lopez-Llano, J.3
Jimenez, M.A.4
Sancho, J.5
-
24
-
-
33747759335
-
The native-state ensemble of proteins provides clues for folding, misfolding and function
-
Cremades, N., Sancho, J., and Freire, E. (2006) The native-state ensemble of proteins provides clues for folding, misfolding and function, Trends Biochem. Sci. 31, 494-496.
-
(2006)
Trends Biochem. Sci
, vol.31
, pp. 494-496
-
-
Cremades, N.1
Sancho, J.2
Freire, E.3
-
25
-
-
0030580089
-
Structure-based calculation of the equilibrium folding pathway of proteins. Correlation with hydrogen exchange protection factors
-
Hilser, V. J., and Freire, E. (1996) Structure-based calculation of the equilibrium folding pathway of proteins. Correlation with hydrogen exchange protection factors, J. Mol. Biol. 262, 756-772.
-
(1996)
J. Mol. Biol
, vol.262
, pp. 756-772
-
-
Hilser, V.J.1
Freire, E.2
-
26
-
-
0030993784
-
Structure-based statistical thermodynamic analysis of T4 lysozyme mutants: Structural mapping of cooperative interactions
-
Hilser, V. J., Townsend, B. D., and Freire, E. (1997) Structure-based statistical thermodynamic analysis of T4 lysozyme mutants: structural mapping of cooperative interactions, Biophys. Chem. 64, 69-79.
-
(1997)
Biophys. Chem
, vol.64
, pp. 69-79
-
-
Hilser, V.J.1
Townsend, B.D.2
Freire, E.3
-
27
-
-
0033642945
-
Structural stability of binding sites: Consequences for binding affinity and allosteric effects
-
Luque, I., and Freire, E. (2000) Structural stability of binding sites: consequences for binding affinity and allosteric effects, Proteins Suppl. 4, 63-71.
-
(2000)
Proteins Suppl
, vol.4
, pp. 63-71
-
-
Luque, I.1
Freire, E.2
-
28
-
-
0015210981
-
Chemical and physical characterization of the Shethna flavoprotein and apoprotein and kinetics and thermodynamics of flavin analog binding to the apoprotein
-
Edmondson, D. E., and Tollin, G. (1971) Chemical and physical characterization of the Shethna flavoprotein and apoprotein and kinetics and thermodynamics of flavin analog binding to the apoprotein, Biochemistry 10, 124-132.
-
(1971)
Biochemistry
, vol.10
, pp. 124-132
-
-
Edmondson, D.E.1
Tollin, G.2
-
29
-
-
0024448151
-
Calculation of protein extinction coefficients from amino acid sequence data
-
Gill, S. C., and von Hippel, P. H. (1989) Calculation of protein extinction coefficients from amino acid sequence data, Anal. Biochem. 182, 319-326.
-
(1989)
Anal. Biochem
, vol.182
, pp. 319-326
-
-
Gill, S.C.1
von Hippel, P.H.2
-
30
-
-
0026763452
-
Unfolding of trp repressor studied using fluorescence spectroscopic techniques
-
Fernando, T., and Royer, C. A. (1992) Unfolding of trp repressor studied using fluorescence spectroscopic techniques, Biochemistry 31, 6683-6691.
-
(1992)
Biochemistry
, vol.31
, pp. 6683-6691
-
-
Fernando, T.1
Royer, C.A.2
-
31
-
-
0027378450
-
Resolution of the fluorescence equilibrium unfolding profile of tip aporepressor using single tryptophan mutants
-
Royer, C. A., Mann, C. J., and Matthews, C. R. (1993) Resolution of the fluorescence equilibrium unfolding profile of tip aporepressor using single tryptophan mutants, Protein Sci. 2, 1844-1852.
-
(1993)
Protein Sci
, vol.2
, pp. 1844-1852
-
-
Royer, C.A.1
Mann, C.J.2
Matthews, C.R.3
-
32
-
-
0017800059
-
Thermodynamics of transfer ribonucleic acids: The effect of sodium on the thermal unfolding of yeast tRNAPhe
-
Freire, E., and Biltonen, R. L. (1978) Thermodynamics of transfer ribonucleic acids: the effect of sodium on the thermal unfolding of yeast tRNAPhe, Biopolymers 17, 1257-1272.
-
(1978)
Biopolymers
, vol.17
, pp. 1257-1272
-
-
Freire, E.1
Biltonen, R.L.2
-
33
-
-
0016224361
-
A thermodynamic approach to the problem of stabilization of globular protein structure: A calorimetric study
-
Privalov, P. L., and Khechinashvili, N. N. (1974) A thermodynamic approach to the problem of stabilization of globular protein structure: a calorimetric study, J. Mol. Biol. 86, 665-684.
-
(1974)
J. Mol. Biol
, vol.86
, pp. 665-684
-
-
Privalov, P.L.1
Khechinashvili, N.N.2
-
34
-
-
0026734102
-
Two-dimensional differential scanning calorimetry: Simultaneous resolution of intrinsic protein structural energetics and ligand binding interactions by global linkage analysis
-
Straume, M., and Freire, E. (1992) Two-dimensional differential scanning calorimetry: simultaneous resolution of intrinsic protein structural energetics and ligand binding interactions by global linkage analysis, Anal. Biochem. 203, 259-268.
-
(1992)
Anal. Biochem
, vol.203
, pp. 259-268
-
-
Straume, M.1
Freire, E.2
-
35
-
-
0017836908
-
Statistical mechanical deconvolution of thermal transitions in macromolecules. I. Theory and application to homogeneous systems
-
Freire, E., and Biltonen, R. L. (1978) Statistical mechanical deconvolution of thermal transitions in macromolecules. I. Theory and application to homogeneous systems, Biopolymers 17, 463-479.
-
(1978)
Biopolymers
, vol.17
, pp. 463-479
-
-
Freire, E.1
Biltonen, R.L.2
-
36
-
-
0026756702
-
Thermodynamics of structural stability and cooperative folding behavior in proteins
-
Murphy, K. P., and Freire, E. (1992) Thermodynamics of structural stability and cooperative folding behavior in proteins, Adv. Protein Chem. 43, 313-361.
-
(1992)
Adv. Protein Chem
, vol.43
, pp. 313-361
-
-
Murphy, K.P.1
Freire, E.2
-
37
-
-
0028146012
-
Structure based prediction of protein folding intermediates
-
Xie, D., and Freire, E. (1994) Structure based prediction of protein folding intermediates, J. Mol. Biol. 242, 62-80.
-
(1994)
J. Mol. Biol
, vol.242
, pp. 62-80
-
-
Xie, D.1
Freire, E.2
-
38
-
-
0029114703
-
The heat capacity of proteins
-
Gomez, J., Hilser, V. J., Xie, D., and Freire, E. (1995) The heat capacity of proteins, Proteins 22, 404-412.
-
(1995)
Proteins
, vol.22
, pp. 404-412
-
-
Gomez, J.1
Hilser, V.J.2
Xie, D.3
Freire, E.4
-
39
-
-
0026649261
-
Molecular basis of co-operativity in protein folding. III. Structural identification of cooperative folding units and folding intermediates
-
Murphy, K. P., Bhakuni, V., Xie, D., and Freire, E. (1992) Molecular basis of co-operativity in protein folding. III. Structural identification of cooperative folding units and folding intermediates, J. Mol. Biol. 227, 293-306.
-
(1992)
J. Mol. Biol
, vol.227
, pp. 293-306
-
-
Murphy, K.P.1
Bhakuni, V.2
Xie, D.3
Freire, E.4
-
40
-
-
38849118238
-
-
Zorrilla, S. (1998) in Departamento de Bioquímica y Biología Molecular., Máster Thesis Biochemistry Department, Zaragoza University (Spain), Zaragoza.
-
Zorrilla, S. (1998) in Departamento de Bioquímica y Biología Molecular., Máster Thesis Biochemistry Department, Zaragoza University (Spain), Zaragoza.
-
-
-
-
41
-
-
0035793715
-
Native hydrogen bonds in a molten globule: The apoflavodoxin thermal intermediate
-
Irun, M. P., Garcia-Mira, M. M., Sanchez-Ruiz, J. M., and Sancho, J. (2001) Native hydrogen bonds in a molten globule: the apoflavodoxin thermal intermediate, J. Mol. Biol. 306, 877-888.
-
(2001)
J. Mol. Biol
, vol.306
, pp. 877-888
-
-
Irun, M.P.1
Garcia-Mira, M.M.2
Sanchez-Ruiz, J.M.3
Sancho, J.4
-
42
-
-
33645217096
-
The folding energy landscape of apoflavodoxin is rugged: Hydrogen exchange reveals nonproductive misfolded intermediates
-
Bollen, Y. J., Kamphuis, M. B., and van Mierlo, C. P. (2006) The folding energy landscape of apoflavodoxin is rugged: hydrogen exchange reveals nonproductive misfolded intermediates, Proc. Natl. Acad. Sci. U.S.A. 103, 4095-4100.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A
, vol.103
, pp. 4095-4100
-
-
Bollen, Y.J.1
Kamphuis, M.B.2
van Mierlo, C.P.3
-
43
-
-
13044272912
-
Automated analysis of interatomic contacts in proteins
-
Sobolev, V., Sorokine, A., Prilusky, J., Abola, E. E., and Edelman, M. (1999) Automated analysis of interatomic contacts in proteins, Bioinformatics 15, 327-332.
-
(1999)
Bioinformatics
, vol.15
, pp. 327-332
-
-
Sobolev, V.1
Sorokine, A.2
Prilusky, J.3
Abola, E.E.4
Edelman, M.5
-
44
-
-
7044224471
-
Do proteins always benefit from a stability increase? Relevant and residual stabilisation in a three-state protein by charge optimisation
-
Campos, L. A., Garcia-Mira, M. M., Godoy-Ruiz, R., Sanchez-Ruiz, J. M., and Sancho, J. (2004) Do proteins always benefit from a stability increase? Relevant and residual stabilisation in a three-state protein by charge optimisation, J. Mol. Biol. 344, 223-237.
-
(2004)
J. Mol. Biol
, vol.344
, pp. 223-237
-
-
Campos, L.A.1
Garcia-Mira, M.M.2
Godoy-Ruiz, R.3
Sanchez-Ruiz, J.M.4
Sancho, J.5
-
45
-
-
0037453260
-
Phase diagrams: A graphical representation of linkage relations
-
Rosgen, J., and Hinz, H. J. (2003) Phase diagrams: a graphical representation of linkage relations, J. Mol. Biol. 328, 255-271.
-
(2003)
J. Mol. Biol
, vol.328
, pp. 255-271
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Rosgen, J.1
Hinz, H.J.2
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