Synthesis, cytotoxic evaluation, and DNA binding of novel thiazolo[5,4-b]quinoline derivatives

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 3, 2008, Pages 1142-1149

  Loza Mejía, Marco A ^a   Maldonado Hernández, Karina ^a   Rodríguez Hernández, Fernando ^a   Rodríguez Sotres, Rogelio ^a   González Sánchez, Ignacio ^a   Quintero, Angelina ^a   Solano, José D ^a   Lira Rocha, Alfonso ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Antitumoral; Cytotoxic activity; DNA binding; Structure activity relationship; Thiazolo 5,4 b quinoline derivatives

Indexed keywords

9 CHLORO 2 [[2 (N,N DIETHYLAMINO)ETHYL]AMINO]THIAZOLO[5,4 B]QUINOLINE; 9 [[(3 CHLORO)PHENYL]AMINO] 2 (METHYLTHIO)THIAZOLO[5,4 B]QUINOLINE; 9 [[(3 CYANO)PHENYL]AMINO] 2 (METHYLTHIO)THIAZOLO[5,4 B]QUINOLINE; 9 [[(3 HYDROXY)PHENYL]AMINO] 2 (METHYLTHIO)THIAZOLO[5,4 B]QUINOLINE; 9 [[(3 METHOXY)PHENYL]AMINO] 2 (METHYLTHIO)THIAZOLO[5,4 B]QUINOLINE; 9 [[(3 N METHYLAMINO)PHENYL]AMINO] 2 (METHYLTHIO)THIAZOLO[5,4 B]QUINOLINE; 9 [[(3 NITRO)PHENYL]AMINO] 2 (METHYLTHIO)THIAZOLO[5,4 B]QUINOLINE; 9 [[(3 TRIFLUOROMETHYL)PHENYL]AMINO] 2 (METHYLTHIO)THIAZOLO[5,4 B]QUINOLINE; 9 [[(4 CHLORO)PHENYL]AMINO] 2 (METHYLTHIO)THIAZOLO[5,4 B]QUINOLINE; 9 [[(4 CYANO)PHENYL]AMINO] 2 (METHYLTHIO)THIAZOLO[5,4 B]QUINOLINE; 9 [[(4 METHOXY)PHENYL]AMINO] 2 (METHYLTHIO)THIAZOLO[5,4 B]QUINOLINE; 9 [[2 (N,N DIETHYLAMINO)]ETHYL]AMINO] 2 (METHYLTHIO)THIAZOLO[5,4 B]QUINOLINE; 9 [[[3 [2 (N,N DIETHYLAMINO)ETHYL]CARBAMOYL]PHENYL]AMINO] 2 (METHYLTHIO)THIAZOLO[5,4 B]QUINOLINE; AMSACRINE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DNA BINDING; DRUG SCREENING; DRUG SYNTHESIS; ELECTRON TRANSPORT; FEMALE; HUMAN; HUMAN CELL; HYDROGEN BOND; IN VITRO STUDY;

EID: 38849124326     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.10.084     Document Type: Article

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