Targeting ACE and ECE with dual acting inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 3, 2008, Pages 1058-1062

  Hanessian, Stephen ^a   Guesné, Sébastien ^a   Riber, Ludivine ^a   Marin, Julien ^a   Benoist, Alain ^b   Mennecier, Philippe ^b   Rupin, Alain ^b   Verbeuren, Tony J ^b   Nanteuil, Guillaume De ^b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

Dual ECE ACE enzyme inhibitors; SA6817 analogues

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIN CONVERTING ENZYME INHIBITOR; ENKEPHALINASE INHIBITOR; MEMBRANE METALLOENDOPEPTIDASE; SA 6817; UNCLASSIFIED DRUG;

ARTICLE; DRUG MECHANISM; ENZYME INHIBITION; IC 50;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ASPARTIC ENDOPEPTIDASES; COMBINATORIAL CHEMISTRY TECHNIQUES; HUMANS; METALLOENDOPEPTIDASES; MOLECULAR STRUCTURE; NAPHTHALENES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; UREA;

EID: 38849113978     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.12.013     Document Type: Article

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