Hypothalamic paraventricular nucleus is critical for renal vasoconstriction elicited by elevations in body temperature

American Journal of Physiology - Renal Physiology

Volumn 294, Issue 2, 2008, Pages

  Cham, Joo Lee ^a   Badoer, Emilio ^a  

^a RMIT UNIVERSITY   (Australia)

Author keywords

Hyperthermia

Indexed keywords

MUSCIMOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; BRAIN REGION; CONTROLLED STUDY; HEART RATE; HYPERTHERMIA; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN TEMPERATURE; VASOCONSTRICTION;

EID: 38849110066     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00488.2007     Document Type: Article

References (30)

1. American Physiological Society. Guiding principles for research involving animals and human beings. Am J Physiol Regul Integr Comp Physiol 283: R281-R283, 2002.
2. Bachtell RK, Tsivkovskaia NO, Ryabinin AE. Identification of temperature-sensitive neural circuits in mice using c-Fos expression mapping. Brain Res 960: 157-164, 2003.
3. Badoer E. Cardiovascular role of parvocellular neurones in the paraventricular nucleus of the hypothalamus. News Physiol Sci 11: 43-47, 1996.
4. Bratincsak A, Palkovits M. Activation of brain areas in rat following warm and cold ambient exposure. Neuroscience 127: 385-397, 2004.
5. Cechetto D, Saper CB. Neurochemical organisation of the hypothalamic projection to the spinal cord in the rat. J Comp Neurol 272: 579-604, 1988.
6. Cham JL, Klein R, Owens NC, Mathai ML, McKinley MJ, Badoer E. Activation of spinally-projecting and nitrergic neurons in the PVN following heat exposure. Am J Physiol Regul Integr Comp Physiol 291: R91-R101, 2006.
7. Harikai N, Tomogane K, Sugawara T, Tashiro S. Differences in hypothalamic Fos expression between two heat stress conditions in conscious mice. Brain Res Bull 61: 617-626, 2003.
8. Haselton JR, Goering J, Patel KP. Parvocellular neurons of the paraventricular nucleus are involved in the reduction in renal nerve discharge during isotonic volume expansion. J Auton Nerv Syst 50: 1-11, 1994.
9. Haselton JR, Vari RC. Neuronal cell bodies in paraventricular nucleus affect renal hemodynamics and excretion via the renal nerves. Am J Physiol Regul Integr Comp Physiol 275: R1334-R1342, 1998.
10. Hubschle T, Mathai M, McKinley M, Oldfield B. Multisynaptic neuronal pathways from the submandibular and sublingual glands to the lamina terminalis in the rat: a model for the role of the lamina terminalis in hte control of osmo- and thermoregulatory behaviour. Clin Exp Pharmacol Physiol 28: 558-569, 2001.
11. Inenaga K, Osaka T, Yamashita H. Thermosensitivity of neurons in the paraventricular nucleus of the rat slice preparation. Brain Res 424: 126-132, 1987.
12. Kannan H, Hayashida Y, Yamashita H. Increase in sympathetic outflow by paraventricular nucleus stimulation in awake rats. Am J Physiol Regul Integr Comp Physiol 256: R1325-R1330, 1989.
13. Kenney MJ, Musch TI, Weiss ML. Renal sympathetic nerve regulation to heating is altered in rats with heart failure. Am J Physiol Heart Circ Physiol 280: H2868-H2875, 2001.
14. Kenney MJ, Pickar JG, Weiss M, Saindon CS, Fels RJ. Effects of midbrain and spinal cord transections on sympathetic nerve responses to heating. Am J Physiol Regul Integr Comp Physiol 278: R1329-R1338, 2000.
15. Kiyohara T, Miyata S, Nakamura T, Shido O, Nakashima T, Shibata M. Differences in Fos expression in the rat brains between cold and warm ambient exposures. Brain Res Bull 38: 193-201, 1995.
16. Lovick TA, Malpas S, Mahony MT. Renal vasodilatation in response to acute volume load is attenuated following lesions of parvocellular neurones in the paraventricular nucleus in rats. J Auton Nerv Syst 43: 247-255, 1993.
17. Malpas SC, Coote JH. Role of vasopressin in sympathetic response to paraventricular nucleus stimulation in anesthetized rats. Am J Physiol Regul Integr Comp Physiol 266: R228-R236, 1994.
18. McKitrick DJ. Expression of Fos in the hypothalamus of rats exposed to warm and cold temperatures. Brain Res Bull 53: 307-315, 2000.
19. Morrison SF. RVLM and raphe differentially regulate sympathetic outflows to splanchnic and brown adipose tissue. Am J Physiol Regul Integr Comp Physiol 276: R962-R973, 1999.
20. Ng CW, De Matteo R, Badoer E. Effect of muscimol and L-NAME in the PVN on the RSNA response to volume expansion in conscious rabbits. Am J Physiol Renal Physiol 287: F739-F746, 2004.
21. Oldfield B, Giles ME, Watson A, Anderson CR, Colvill L, McKinley MJ. The neurochemical characterisation of hypothalamic pathways projecting to brown adipose tissue in the rat. Neuroscience 110: 515-526, 2002.
22. Owens NC, Ootsuka Y, Kanosue K, McAllen RM. Thermoregulatory control of sympathetic fibres supplying the rat's tail. J Physiol 543: 849-858, 2002.
23. Raman ER, Roberts MF, Vanhuyse VJ. Body temperature control of rat tail blood flow. Am J Physiol Regul Integr Comp Physiol 245: R426-R432, 1983.
24. Rathner JA, McAllen RM. Differential control of sympathetic drive to the rat tail artery and kidney by medullary premotor cell groups. Brain Res 834: 196-199, 1999.
25. Shafton AD, Ryan AR, Badoer E. Neurons in the hypothalamic paraventricular nucleus send collaterals to the spinal cord and to the rostal ventrolateral medulla in the rat. Brain Res 801: 239-243, 1998.
26. Smith JE, JAnsen AS, Gilbey MP, Loewy AD. CNS cell groups projecting to sympathetic outflow of tail artery: neural circuits involved in heat loss in the rat. Brain Res 786: 153-164, 1998.
27. Swanson LW, Sawchenko PE. Hypothalamic integration: organization of the paraventricular and supraoptic nuclei. Ann Rev Neurosci 6: 269-324, 1983.
28. Swanson LW, Sawchenko PE, Wiegand SJ, Price JL. Separate neurons in the paraventricular nucleus project to the median eminence and to the medulla or spinal cord. Brain Res 198: 190-195, 1980.
29. Tagawa T, Dampney RAL. AT1 receptors mediate excitatory inputs to rostral ventrolateral medulla pressor neurons from hypothalamus. Hypertension 34: 1301-1307, 1999.
30. Tanaka M, Nagashima K, McAllen RM, Kanosue K. Role of the medullary raphé in thermoregulatory vasomotor control in rats. J Physiol 540: 657-664, 2002.