An efficient synthetic route to novel 3-alkyl- and 3-aryl-4-iodophenols

Synthesis

Volumn , Issue 2, 2008, Pages 221-224

  Hermann, Gesine J ^a   Annis, Michael C ^a   Edwards, Peter D ^a   Corrales, Marta ^a   Díaz, Lucía ^a   Goodnow, Robert A ^b  

^a ChemOvation Ltd   (United Kingdom)

^b HOFFMANN LA ROCHE INC   (United States)

Author keywords

Deiodination; Halogenation; Iodine monochloride; Phenols; Suzuki reaction

Indexed keywords

ARYLPHENOLS; DEIODINATION; IODINE MONOCHLORIDE; IODOPHENOLS; SUZUKI REACTION;

HALOGENATION; IODINE COMPOUNDS; REACTION KINETICS;

PHENOLS;

2 BROMO 5 TERT BUTYLPHENOL; 2 IODO 5 ISOPROPYLPHENOL; 2,4 DIIODO 5 ISOPROPYLPHENOL; 3 TERT BUTYL 4 IODOPHENOL; 4 BROMO 3 TERT BUTYLPHENOL; 4 IODO 3 ISOPROPYLPHENOL; 4 IODOBIPHENYL 3 OL; 4 IODOPHENOL DERIVATIVE; 4,6 DIIODOBIPHENYL 3 OL; 5 TERT BUTYL 2 IODOPHENOL; 5 TERT BUTYL 2,4 DIIODOPHENOL; 6 IODOBIPHENYL 3 OL; PHENOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; DEIODINATION; HALOGENATION; SUZUKI REACTION; SYNTHESIS;

EID: 38849104331     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1000860     Document Type: Article

References (9)

1. Merkushev, E. B. Synthesis 1988, 923.
2. Doad, G. J. S.; Barltrop, J. A.; Petty, C. M.; Owen, T. C. Tetrahedron Lett. 1989, 30, 1597.
3. Espuña, G.; Arsequell, G.; Valencia, G.; Barluenga, J.; Pérez, M.; González, J. M. Chem. Commun. 2000, 1307.
4. Narender, N.; Srinivasu, P.; Kulkarni, S. J.; Raghavan, K. V. Synth. Commun. 2002, 32, 2319.
5. Edgar, K. J.; Falling, S. N. J. Org. Chem. 1990, 55, 5287.
6. Doad, G. J. S.; Barltrop, J. A.; Petty, C. M.; Owen, T. C. Tetrahedron Lett. 1989, 30, 1597.
7. Fukata, G.; Kubota, Y.; Mataka, S.; Thiemann, T.; Tashiro, M. Bull. Chem. Soc. Jpn. 1994, 67, 592.
8. Morinaka, H.; Nakanishi, A.; Nonaka, Y. US 4,668,831, 1987.
9. Talekar, R. S.; Chen, G. S.; Lai, S.-Y.; Chern, J.-W. J. Org. Chem. 2005, 70, 8590.