Effects of confinement on the mechanical properties of self-assembled articular cartilage constructs in the direction orthogonal to the confinement surface

Journal of Orthopaedic Research

Volumn 26, Issue 2, 2008, Pages 238-246

  Elder, Benjamin D ^a   Athanasiou, Kyriacos A ^a  

^a Rice University   (United States)

Author keywords

Articular cartilage; Extracellular matrix; Mechanical stimulation; Self assembling process; Tissue engineering

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 2; DNA; GLYCOSAMINOGLYCAN; COLLAGEN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BIOCHEMISTRY; BIOMECHANICS; COLLAGEN SYNTHESIS; COMPRESSIVE STRENGTH; CONTROLLED STUDY; HISTOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; RIGIDITY; SURFACE PROPERTY; TENSILE STRENGTH; TISSUE ENGINEERING; YOUNG MODULUS; ANIMAL; BIOLOGICAL MODEL; CARTILAGE CELL; CATTLE; CELL CULTURE; CHEMISTRY; CULTURE TECHNIQUE; FEMUR; MECHANICAL STRESS; METABOLISM; METHODOLOGY; PATHOLOGY; PHYSIOLOGY;

ANIMALS; BIOMECHANICS; CARTILAGE, ARTICULAR; CATTLE; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CHONDROCYTES; COLLAGEN; FEMUR; GLYCOSAMINOGLYCANS; MALE; MODELS, BIOLOGICAL; STRESS, MECHANICAL; TENSILE STRENGTH; TISSUE ENGINEERING;

EID: 38849092216     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20480     Document Type: Article

References (35)

1. Buckwalter JA. 1998. Articular cartilage: injuries and potential for healing. J Orthop Sports Phys Ther 28:192-202.
2. Hu JC, Athanasiou KA. 2006. A self-assembling process in articular cartilage tissue engineering. Tissue Eng 12:969-979.
3. Hu JC, Athanasiou KA. 2006. The effects of intermittent hydrostatic pressure on self-assembled articular cartilage constructs. Tissue Eng 12:1337-1344.
4. Helminen HJ, Saamanen AM, Jurvelin J, et al. 1992. [The effect of loading on articular cartilage]. Duodecim 108: 1097-1107.
5. Palmoski MJ, Colyer RA, Brandt KD. 1980. Joint motion in the absence of normal loading does not maintain normal articular cartilage. Arthritis Rheum 23:325-334.
6. Hunter CJ, Imler SM, Malaviya P, et al. 2002. Mechanical compression alters gene expression and extracellular matrix synthesis by chondrocytes cultured in collagen I gels. Biomaterials 23:1249-1259.
7. Sah RL, Kim YJ, Doong JY, et al. 1989. Biosynthetic response of cartilage explants to dynamic compression. J Orthop Res 7:619-636.
8. AufderHeide AC, Athanasiou KA. Mechanical stimulation toward tissue engineering of the knee meniscus. Ann Biomed Eng 2004; 32:1161-1174.
9. Mauck RL, Soltz MA, Wang CC, et al. 2000. Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels. J Biomech Eng 122:252-260.
10. Stoddart MJ, Ettinger L, Hauselmann HJ. 2006. Enhanced matrix synthesis in de novo, scaffold free cartilage-like tissue subjected to compression and shear. Biotechnol Bioeng 95:1043-1051.
11. Waldman SD, Spiteri CG, Grynpas MD, et al. 2003. Effect of biomechanical conditioning on cartilaginous tissue formation in vitro. J Bone Joint Surg [Am] 85-A (Suppl 2):101-105.
12. Waldman SD, Spiteri CG, Grynpas MD, et al. 2004. Long-term intermittent compressive stimulation improves the composition and mechanical properties of tissue-engineered cartilage. Tissue Eng 10:1323-1331.
13. Waldman SD, Spiteri CG, Grynpas MD, et al. 2003. Long-term intermittent shear deformation improves the quality of cartilaginous tissue formed in vitro. J Orthop Res 21: 590-596.
14. Almarza AJ, Athanasiou KA. 2006. Effects of hydrostatic pressure on TMJ disc cells. Tissue Eng 12:1285-1294.
15. Hu JC, Athanasiou KA. 2006. The effects of intermittent hydrostatic pressure on self-assembled articular cartilage constructs. Tissue Eng 12:1337-1344.
16. Hall AC, Urban JP, Gehl KA. 1991. The effects of hydrostatic pressure on matrix synthesis in articular cartilage. J Orthop Res 9:1-10.
17. Lammi MJ, Elo MA, Sironen RK, et al. 2004. Hydrostatic pressure-induced changes in cellular protein synthesis. Biorheology 41:309-313.
18. Kelly TA, Wang CC, Mauck RL, et al. 2004. Role of cell-associated matrix in the development of free-swelling and dynamically loaded chondrocyte-seeded agarose gels. Biorheology 41:223-237.
19. Khalafi A, Schmid TM, Neu C, et al. 2007. Increased accumulation of superficial zone protein (SZP) in articular cartilage in response to bone morphogenetic protein-7 and growth factors. J Orthop Res 25:293-303.
20. Mauck RL, Nicoll SB, Seyhan SL, et al. 2003. Synergistic action of growth factors and dynamic loading for articular cartilage tissue engineering. Tissue Eng 9:597-611.
21. Saini S, Wick TM. 2004. Effect of low oxygen tension on tissue-engineered cartilage construct development in the concentric cylinder bioreactor. Tissue Eng 10:825-832.
22. Shimizu M, Minakuchi K, Kaji S, et al. 1997. Chondrocyte migration to fibronectin, type I collagen, and type II collagen. Cell Struct Funct 22:309-315.
23. Rosenberg L. 1971. Chemical basis for the histological use of safranin O in the study of articular cartilage. J Bone Joint Surg [Am] 53:69-82.
24. Brown AN, Kim BS, Alsberg E, et al. 2000. Combining chondrocytes and smooth muscle cells to engineer hybrid soft tissue constructs. Tissue Eng 6:297-305.
25. Pietila K, Kantomaa T, Pirttiniemi P, et al. 1999. Comparison of amounts and properties of collagen and proteoglycans in condylar, costal and nasal cartilages. Cells Tissues Organs 164:30-36.
26. Woessner JF Jr. 1961. The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch Biochem Biophys 93: 440-447.
27. Athanasiou KA, Agarwal A, Dzida FJ. 1994. Comparative study of the intrinsic mechanical properties of the human acetabular and femoral head cartilage. J Orthop Res 12:340-349.
28. Sneddon I. 1965. The relaxation between load and penetration in the axisymmetric Boussinesq problem for a punch of arbitrary profile. Int J Eng Sci 3:47-57.
29. Hayes WC, Keer LM, Herrmann G, et al. 1972. A mathematical analysis for indentation tests of articular cartilage. J Biomech 5:541-551.
30. Mow VC, Kuei SC, Lai WM, et al. 1980. Biphasic creep and stress relaxation of articular cartilage in compression. Theory and experiments. J Biomech Eng 102:73-84.
31. Detamore MS, Athanasiou KA. 2003. Tensile properties of the porcine temporomandibular joint disc. J Biomech Eng 125:558-565.
32. Mauck RL, Wang CC, Oswald ES, et al. 2003. The role of cell seeding density and nutrient supply for articular cartilage tissue engineering with deformational loading. Osteoarthritis Cartilage 11:879-890.
33. Kelly TA, Ng KW, Wang CC, et al. 2006. Spatial and temporal development of chondrocyte-seeded agarose constructs in free-swelling and dynamically loaded cultures. J Biomech 39:1489-1497.
34. Kiviranta P, Rieppo J, Korhonen RK, et al. 2006. Collagen network primarily controls Poisson's ratio of bovine articular cartilage in compression. J Orthop Res 24:690-699.
35. Boustany NN, Gray ML, Black AC, et al. 1995. Time-dependent changes in the response of cartilage to static compression suggest interstitial pH is not the only signaling mechanism. J Orthop Res 13:740-750.