Sulfonamide-1,2,4-triazole derivatives as antifungal and antibacterial agents: Synthesis, biological evaluation, lipophilicity, and conformational studies

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 3, 2008, Pages 1150-1161

  Ezabadi, Iraj Rahavi ^a   Camoutsis, Charalabos ^a   Zoumpoulakis, Panagiotis ^b   Geronikaki, Athina ^c   Soković, Marina ^d   Glamočilija, Jasmina ^d   Ćirić, Ana ^d  

^a School of Health Sciences   (Greece)

^b INSTITUTE OF BIOLOGY   (Greece)

^c ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^d Institute for Biological Research   (Serbia)

Author keywords

Antibacterial; Antifungal; Conformational properties; Lipophilicity; Triazoles

Indexed keywords

5 [2 (1 PIPERIDINESULFAMOYL) 4,5 DIMETHOXYBENZYL] 4 (4 CHLOROPHENYL)TRIAZOLE 3 THIONE; 5 [2 (1 PIPERIDINESULFAMOYL) 4,5 DIMETHOXYBENZYL] 4 PHENYLTRIAZOLE 3 THIONE; 5 [2 (1 PYRROLIDINESULFAMOYL) 4,5 DIMETHOXYBENZYL] 4 (4 CHLOROPHENYL)TRIAZOLE 3 THIONE; 5 [2 (1 PYRROLIDINESULFAMOYL) 4,5 DIMETHOXYBENZYL] 4 PHENYLTRIAZOLE 3 THIONE; 5 [2 (4 MORPHOLINESULFAMOYL) 4,5 DIMETHOXYBENZYL] 4 (4 CHLOROPHENYL)TRIAZOLE 3 THIONE; 5 [2 (4 MORPHOLINESULFAMOYL) 4,5 DIMETHOXYBENZYL] 4 PHENYLTRIAZOLE 3 THIONE; 5 [2 (N DIETHYLSULFAMOYL) 4,5 DIMETHOXYBENZYL] 4 (4 CHLOROPHENYL)TRIAZOLE 3 THIONE; 5 [2 (N DIETHYLSULFAMOYL) 4,5 DIMETHOXYBENZYL] 4 PHENYLTRIAZOLE 3 THIONE; 5 [2 (N DIMETHYLSULFAMOYL) 4,5 DIMETHOXYBENZYL] 4 (4 CHLOROPHENYL)TRIAZOLE 3 THIONE; 5 [2 (N DIMETHYLSULFAMOYL) 4,5 DIMETHOXYBENZYL] 4 PHENYLTRIAZOLE 3 THIONE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; BIFONAZOLE; CHLORAMPHENICOL; STREPTOMYCIN; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG CONFORMATION; DRUG SCREENING; DRUG SYNTHESIS; ENTEROBACTER CLOACAE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; LIPOPHILICITY; MICROMYCETE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; SALMONELLA; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; ASPERGILLUS; ENTEROBACTER CLOACAE; LIPIDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; SALMONELLA; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; TRIAZOLES; TRICHODERMA;

ENTEROBACTER; SALMONELLA;

EID: 38849090006     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.10.082     Document Type: Article

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