Combination of O6-methylguanine-DNA methyltransferase and thymidylate synthase for the prediction of fluoropyrimidine efficacy

European Journal of Cancer

Volumn 44, Issue 3, 2008, Pages 400-407

  Nakajima, Takako Eguchi ^a   Yamada, Yasuhide ^a   Shimoda, Tadakazu ^a   Matsubara, Junichi ^a   Kato, Ken ^a   Hamaguchi, Tetsuya ^a   Shimada, Yasuhiro ^a   Okayama, Yoshihiro ^b   Oka, Toshinori ^b   Shirao, Kuniaki ^a  

^a NATIONAL CANCER CENTER HOSPITAL   (Japan)

^b TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Colorectal cancer; Fluoropyrimidine; Irinotecan; MGMT; TS

Indexed keywords

CYCLIN E; FLUOROPYRIMIDINE; FLUOROURACIL; FOLINIC ACID; GAMMA GLUTAMYL HYDROLASE; IRINOTECAN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MITOMYCIN C; MOLECULAR MARKER; THYMIDYLATE SYNTHASE; TS 1; UFT; UNCLASSIFIED DRUG; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; COLORECTAL CANCER; COMBINATION CHEMOTHERAPY; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; MULTIPLE CYCLE TREATMENT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; TREATMENT OUTCOME; TREATMENT RESPONSE; COLORECTAL TUMOR; DNA METHYLATION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; METASTASIS; MIDDLE AGED; MORTALITY; PREDICTION AND FORECASTING; RETROSPECTIVE STUDY; SURVIVAL;

ADULT; AGED; COLORECTAL NEOPLASMS; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MIDDLE AGED; NEOPLASM METASTASIS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; THYMIDYLATE SYNTHASE; TUMOR MARKERS, BIOLOGICAL;

EID: 38749136630     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2007.11.010     Document Type: Article

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