Decreasing incidence of symptomatic gastrointestinal ulcers and ulcer complications in patients with rheumatoid arthritis

Annals of the Rheumatic Diseases

Volumn 67, Issue 2, 2008, Pages 256-259

  Steen, K S S ^a   Nurmohamed, M T ^a   Visman, I ^b   Heijerman, M ^b   Boers, M ^a   Dijkmans, B A C ^a   Lems, W F ^c  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b JAN VAN BREEMEN INSTITUTE   (Netherlands)

^c SLOTERVAART HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; CYCLOOXYGENASE 2 INHIBITOR; HISTAMINE H2 RECEPTOR ANTAGONIST; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN DERIVATIVE; PROTON PUMP INHIBITOR;

ACID REGURGITATION; ADULT; AGED; ANAMNESIS; ARTICLE; BELCHING; BLOATING; CONFIDENCE INTERVAL; CONTROLLED STUDY; DE LANGE SYNDROME; DIGESTIVE SYSTEM ULCER; DYSPEPSIA; EPIGASTRIC PAIN; FEMALE; HEARTBURN; HIGH RISK PATIENT; HUMAN; HUNGER PAIN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; NAUSEA; OBSERVATIONAL STUDY; OUTPATIENT DEPARTMENT; PRACTICE GUIDELINE; PRESCRIPTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; RHEUMATOID ARTHRITIS; STATISTICAL SIGNIFICANCE; STOMACH DISEASE; UNITED STATES;

ADULT; AGED; AGED, 80 AND OVER; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, RHEUMATOID; CYCLOOXYGENASE INHIBITORS; FEMALE; HUMANS; INCIDENCE; INTESTINAL DISEASES; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; QUESTIONNAIRES; STOMACH ULCER; ULCER;

EID: 38749135514     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2006.068015     Document Type: Article

References (11)

1. Roth SH. NSAID gastropathy. A new understanding. Arch Intern Med 1996;156:1623-8.
2. Wolfe MM, Lichtenstein DR, Singh G. Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs [review]. N Engl J Med 1999;340:1888-99.
3. Laine L. The gastrointestinal effects of nonselective NSAIDs and COX-2-selective inhibitors. Semin Arthritis Rheum 2002;32(3 Suppl 1):25-32.
4. Steen KSS, Lems WF, Aertsen J, Bezemer D, Dijkmans BAC. Incidence of clinically manifest ulcers and their complications in patients with rheumatoid arthritis. Ann Rheum Dis 2001;60:443-7.
5. Fries JF, Murtagh KN, Bennett M, Zatarain E, Lingala B, Bruce B. The rise and decline of nonsteroidal antiinflammatory drug-associated gastropathy in rheumatoid arthritis. Arthritis Rheum 2004;50:2433- 40.
6. Voskuyl AE, Van de Laar MA, Moens HJ, Van der Korst. Extra-articular manifestations of rheumatoid arthritis: risk factors for serious gastrointestinal events. Ann Rheum Dis 1993;52:771-5.
7. Moens HJ, van Croonenborg JJ, Al MJ, van den Bemt PM, Lourens J, Numans ME, Working Group. Guideline NSAID use and the prevention of gastric damage [in Dutch]. Ned Tijdschr Geneeskd 2004;148:604-6.
8. Rostom A, Dube C, Wells G, Tugwell P, Welch V, Jolicoeur E, et al. Prevention of NSAID-induced gastroduodenal ulcers. Cochrane Database Syst Rev 2002;4:CD002296.
9. Hawkey CJ, Tulassay Z, Szczepanski L, van Rensburg CJ, Filipowicz-Sosnowska A, Lanas A, et al. Randomised controlled trial of Helicobacter pylori eradication in patients on non-steroidal anti-inflammatory drugs. HELP NSAIDSs study. Lancet 1998;352:1016- 21.
10. Chan FK, To KF, Wu JC, Yung MY, Leung WK, Kwok T, et al. Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: a randomised trial. Lancet 2002;359:9-13.
11. De Leest HTJI, Steen KSS, Lems WF, Bijlsma JWJ, van de Laar MAFJ, Huisman AM, et al. Eradication of Helicobacter pylori does not reduce the incidence of gastroduodenal ulcers in patients on long-term NSAID-treatment. A randomised, double blind, placebo controlled trial. Helicobacter 2007;12:477-85.