Suppression of SCC antigen promotes cancer cell invasion and migration through the decrease in E-cadherin expression

International Journal of Oncology

Volumn 29, Issue 5, 2006, Pages 1231-1235

  Murakami, Akihiro ^a   Nakagawa, Tatsushi ^a   Kaneko, Mayumi ^a   Nawata, Shugo ^a   Takeda, Osamu ^a   Kato, Hiroshi ^a   Sugino, Norihiro ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cell migration and invasion; E cadherin; SCC antigen

Indexed keywords

CADHERIN; COMPLEMENTARY DNA; SERINE PROTEINASE INHIBITOR; SQUAMOUS CELL CARCINOMA RELATED ANTIGEN; SQUAMOUS CELL CARCINOMA-RELATED ANTIGEN; TUMOR ANTIGEN;

ARTICLE; CANCER INVASION; CELL ADHESION; CELL MOTION; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; PHYSIOLOGY; TUMOR CELL LINE;

ANTIGENS, NEOPLASM; CADHERINS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; DNA, ANTISENSE; HUMANS; NEOPLASM INVASIVENESS; SERPINS;

EID: 38749127315     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.29.5.1231     Document Type: Article

References (26)

1. Kato H and Torigoe T: Radioimmunoassay for tumour antigen of human cervical squamous cell carcinoma. Cancer 40: 1621-1628, 1977.
2. Kato H, Tamai K, Morioka H, Nagai M, Nagaya T and Torigoe T: Prognostic significance of the tumour antigen TA-4 in squamous cell carcinoma of the uterine cervix. Am J Obstet Gynecol 145: 350-354, 1983.
3. Maruo T, Shibata K, Kimura A, Hoshina A and Mochizuki M: Tumour-associated antigen, TA-4, in the monitoring of the effects of therapy for squamous cell carcinoma of the uterine cervix. Cancer 59: 302-308, 1985.
4. Brioschi PA, Bischof P, Delafosse C and Krauer F: Squamous-cell carcinoma antigen (SCC-A) values related to clinical outcome of pre-invasive and invasive cervical carcinoma. Int J Cancer 47: 376-379, 1991.
5. Schneider SS, Schick C, Fish KE, Miller E, Pena JC, Treter SD, Hui SM and Silverman GA: A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene. Proc Natl Acad Sci USA 92: 3147-3151, 1995.
6. Kuwano A, Kondo I, Kishi F, Suminami Y and Kato H: Assignment of the squamous cell carcinoma antigen locus (SCC) to 18q21 by in situ hybridization. Genomics 30: 626, 1995.
7. Suminami Y, Kishi F, Sekiguchi K and Kato H: Squamous cell carcinoma antigen is a new member of the serine protease inhibitors. Biochem Biophys Res Commun 181: 51-58, 1991.
8. Nawata S, Tsunaga N, Numa F, Tanaka T, Nakamura K and Kato H: Serine protease inhibitor activity of recombinant squamous cell carcinoma antigen towards chymotrypsin, as demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Electrophoresis 16: 1027-1030, 1995.
9. Nawata S, Nakamura K, Tanaka T, Numa F, Suminami Y, Tsunaga N, Kakegawa H, Katsunuma N and Kato H: Electrophoretic analysis of the 'cross-class' interaction between novel inhibitory serpin, squamous cell carcinoma antigen-1 and cystein proteinases. Electrophoresis 18: 784-789, 1997.
10. Schick C, Kamachi Y, Bartuski AJ, Çataltepe S, Schechter NM, Pemberton PA and Silverman GA: Squamous cell carcinoma antigen 2 is a novel serpin that inhibits the chymotrypsin-like proteinases cathepsin G and mast cell chymase. J Biol Chem 17: 1849-1855, 1997.
11. Schick C, Pemberton PA, Shi GP, Kamachi Y, Çataltepe S, Bartuski AJ, Cornstein ER, Brömme D, Chapman HA and Silverman GA: Cross-class inhibition of the cysteine proteinases cathepsin K, L, S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis. Biochemistry 37: 5258-5266, 1998.
12. Suminami Y, Nagashima S, Vujanovic NL, Hirabayashi K, Kato H and Whiteside TL: Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1. Br J Cancer 82: 981-989, 2000.
13. Murakami A, Suminami Y, Hirakawa H, Nawata S, Numa F and Kato H: Squamous cell carcinoma antigen suppresses radiation-induced cell death. Br J Cancer 84: 851-858, 2001. (Pubitemid 32275662)
14. Schipper JH, Frixen UH, Behrens J, Unger A, Jahnke K and Birchmeier W: E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumour dedifferentiation and lymph node metastasis. Cancer Res 51: 6328-6337, 1991.
15. Murakami A, Suminami Y, Sakaguchi Y, Nawata S, Numa F, Kishi F and Kato H: Specific detection and quantitation of SCC antigen 1 and SCC antigen 2 mRNAs by fluorescence-based asymmetric semi-nested reverse transcription PCR. Tumour Biol 21: 224-234, 2000.
16. Takeshima N, Suminami Y, Takeda O, Abe H, Okuno N and Kato H: Expression of mRNA of SCC antigen in squamous cells. Tumour Biol 13: 338-342, 1992.
17. De Boer CJ, van Dorst E, van Krieken H, Jansen-van Rhijn CM, Warnaar SO, Fleuren GJ and Litvinov SV: Changing roles of cadherins and catenins during progression of squamous intraepithelial lesions in the uterine cervix. Am J Pathol 155: 505-515, 1999.
18. Nozawa S, Kojima M, Tukazaki K, Sakayori M, Iizuka R and Kagiyama N: In vitro and in vivo induction of squamous cell carcinoma antigen (SCC) in a uterine cervical cancer cell line (SKG IIIa) with peplomycin and sodium butyrate. Asia-Oceania J Obstet Gynecol 16: 153-160, 1990.
19. Sueoka K, Nawata S, Nakagawa T, Murakami A, Takeda O, Suminami Y, Kato H and Sugino N: Tumor-associated serpin, squamous cell carcinoma antigen stimulates matrix metalloproteinase- 9 production in cervical squamous cell carcinoma cell lines. Int J Oncol 27: 1345-1353, 2005.
20. Hirakawa H, Nawata S, Sueoka K, Murakami A, Takeda O, Numa F, Kato H and Sugino N: Regulation of squamous cell carcinoma antigen production by E-cadherin mediated cell-cell adhesion in squamous cell carcinoma cell line. Oncol Rep 11: 415-419, 2004.
21. Shiozaki H, Tahara H, Oka H, Miyata M, Kobayashi K, Tamura S, Iihara K, Doki Y, Hirano S, Takeichi M and Mori T: Expression of immunoreactive E-cadherin adhesion molecules in human cancers. Am J Pathol 139: 17-23, 1991.
22. Kadowaki T, Shiozaki H, Inoue M, Tamura S, Oka H, Doki Y, Iihara K, Matsui S, Iwazawa T, Nagafuchi A, Tsukita S and Mori T: E-cadherin and α-catenin expression in human esophageal cancer. Cancer Res 54: 291-296, 1994.
23. Vessey CJ, Wilding J, Folarin N, Hirano S, Takeichi M, Soutter P, Stamp GWH and Pignatelli M: Altered expression and function of E-cadherin in cervical intraepithelial neoplasia and invasive squamous cell carcinoma. J Pathol 176: 151-159, 1995.
24. Carico E, Atlante M, Bucci B, Nofroni I and Vecchione A: E-cadherin and α-catenin expression during tumour progression of cervical carcinoma. Gynecol Oncol 80: 156-161, 2001.
25. Çataltepe S, Schick C, Luke CJ, Pak SCO, Goldfarb D, Chen P, Tanasiyevic MJ, Posner MR and Silverman GA: Development of specific monoclonal antibodies and a sensitive discriminatory immunoassay for the circulating tumour markers SCCA1 and SCCA2. Clin Chim Acta 295: 107-127, 2000. (Pubitemid 30184803)
26. Iwasaki M, Nishikawa A, Akutagawa N, Fujimoto T, Teramoto M, Sakaguchi Y, Kato H, Ito M, Yoshida K and Kudo R: E1AF/PEA3 reduces the invasiveness of SiHa cervical cancer cells by activating serine proteinase inhibitor squamous cell carcinoma antigen. Exp Cell Res 299: 525-532, 2004. (Pubitemid 39179816)