Antibiotic-impregnated shunt catheters for the treatment of infantile hydrocephalus

Pediatric Neurosurgery

Volumn 44, Issue 2, 2008, Pages 91-96

  Sciubba, Daniel M ^a   Noggle, Joseph C ^a   Carson, Benjamin S ^a   Jallo, George I ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Antibiotic impregnated shunt; Hydrocephalus; Premature patients; Shunt; Ventricular access

Indexed keywords

ANTIBIOTIC AGENT;

ANTIBIOTIC IMPREGNATED SHUNT CATHETER; ARTICLE; BRAIN VENTRICLE PERITONEUM SHUNT; CATHETER; CEREBROSPINAL FLUID SHUNTING; CONTROLLED STUDY; CYSTOPERITONEAL SHUNT; DECOMPRESSION SURGERY; DEVICE; FEMALE; GESTATIONAL AGE; HUMAN; HYDROCEPHALUS; INFANT; INFANT DISEASE; INFECTION PREVENTION; LIQUORRHEA; MAJOR CLINICAL STUDY; MALE; NEWBORN; OBSERVATIONAL STUDY; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PREMATURITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; REOPERATION; SHUNT INFECTION; SURGICAL INFECTION; VENTRICULAR ACCESS DEVICE; VENTRICULOATRIAL SHUNT;

ANTI-BACTERIAL AGENTS; CATHETERIZATION; CEREBROSPINAL FLUID SHUNTS; FEMALE; HUMANS; HYDROCEPHALUS; INFANT; INFANT, NEWBORN; MALE; PROSPECTIVE STUDIES;

EID: 38749115862     PISSN: 10162291     EISSN: None     Source Type: Journal    
DOI: 10.1159/000113109     Document Type: Article

References (20)

1. Vinchon M, Dhellemmes P: Cerebrospinal fluid shunt infection: risk factors and long-term follow-up. Childs Nerv Syst 2006;22:692-697.
2. McGirt M, Zaas A, Fuchs H, George T, Kaye K, Sexton D: Risk factors for pediatric ventriculoperitoneal shunt infection and predictors of infectious pathogens. Clin Infect Dis 2003;36:858-862.
3. Kulkarni AV, Drake JM, Lamberti-Pasculli M: Cerebrospinal fluid shunt infection: a prospective study of risk factors. J Neurosurg 2001;94:195-201.
4. Vinchon M, Lemaitre M, Vallee L, Dhellemmes P: Late shunt infection: incidence, pathogenesis, and therapeutic implications. Neuropediatrics 2002;33:169-173.
5. Haines S, Walters B: Antibiotic prophylaxis for cerebrospinal fluid shunts: a metanalysis. Neurosurgery 1994;34:87-92.
6. Langley J, LeBlanc J, Drake J, Milner R: Efficacy of antimicrobial prophylaxis in placement of cerebrospinal fluid shunts: meta-analysis. Clin Infect Dis 1993;17:98-103.
7. Govender S, Nathoo N, van Dellen J: Evaluation of an antibiotic- impregnated shunt system for the treatment of hydrocephalus. J Neurosurg 2003;99:831-839.
8. Sciubba DM, Stuart RM, McGirt MJ, Woodworth GF, Samdani AF, Carson BS, Jallo GI: Effect of antibiotic-impregnated shunt catheters in decreasing the incidence of shunt infection in the treatment of hydrocephalus. J Neurosurg 2005;103(2 suppl):131-136.
9. George R, Leibrock L, Epstein M: Long-term analysis of cerebrospinal fluid shunt infections. A 25-year experience. J Neurosurg 1979;51:804-811.
10. Enger P, Svendsen F, Wester K: CSF shunt infections in children: experiences from a population-based study. Acta Neurochir (Wien) 2003;145:243-248;discussion 248.
11. Kanev P, Sheehan J: Reflections on shunt infection. Pediatr Neurosurg 2003;39:285-290.
12. Ronan A, Hogg G, Klug G: Cerebrospinal fluid shunt infections in children. Pediatr Infect Dis J 1995;14:782-786.
13. Gardner P, Leipzig T, Phillips P: Infections of central nervous system shunts. Med Clin North Am 1985;69:297-314.
14. Willis BK, Kumar CR, Wylen EL, Nanda A: Ventriculosubgaleal shunts for posthemorrhagic hydrocephalus in premature infants. Pediatr Neurosurg 2005;41:178-185.
15. Roland EH, Hill A: Intraventricular hemorrhage and posthemorrhagic hydrocephalus. Current and potential future interventions. Clin Perinatol 1997;24:589-605.
16. Kockro R, Hampl J, Jansen B, Peters G, Scheihing M, Giacomelli R, Kunze S, Aschoff A: Use of scanning electron microscopy to investigate the prophylactic efficacy of rifampin-impregnated CSF shunt catheters. J Med Microbiol 2000;49:441-450.
17. Kohnen W, Schaper J, Klein O, Tieke B, Jansen B: A silicone ventricular catheter coated with a combination of rifampin and trimethoprim for the prevention of catheter-related infections. Zentralbl Bakteriol 1998;287:147-156.
18. Hampl J, Schierholz J, Jansen B, Aschoff A: In vitro and in vivo efficacy of a rifampin-loaded silicone catheter for the prevention of CSF shunt infections. Acta Neurochir (Wien) 1995;133:147-152.
19. Bayston R, Lambert E: Duration of protective activity of cerebrospinal fluid shunt catheters impregnated with antimicrobial agents to prevent bacterial catheter-related infection. J Neurosurg 1997;87:247-251.
20. Schierholz J, Pulverer G: Development of a new CSF-shunt with sustained release of an antimicrobial broad-spectrum combination. Zentralbl Bakteriol 1997;286:107-123.