Salvianolic acid B promotes survival of transplanted mesenchymal stem cells in spinal cord-injured rats

Acta Pharmacologica Sinica

Volumn 29, Issue 2, 2008, Pages 169-176

  Bi, Xiao Bin ^a   Deng, Yu Bin ^a   Gan, Dan Hui ^a   Wang, Ya Zhu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Cell survival; Mesenchymal stem cells; Salvianolic acid B; Spinal cord injuries

Indexed keywords

BROXURIDINE; PHOSPHATE BUFFERED SALINE; SALVIANOLIC ACID B; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASSO BEATIE BRESNAHAN SCALE; CELL SURVIVAL; CELL THERAPY; CONTROL GROUP; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; INJURY SCALE; MALE; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; NEUROPROTECTION; NONHUMAN; RAT; SPINAL CORD INJURY; STATISTICAL SIGNIFICANCE;

ANIMALS; ANTIOXIDANTS; BEHAVIOR, ANIMAL; BENZOFURANS; CELL SURVIVAL; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD INJURIES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 38749108906     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2008.00710.x     Document Type: Article

References (23)

1. Deng YB, Yuan QT, Liu XG, Liu XL, Liu Y, Liu ZG, et al. Functional recovery after rhesus monkey spinal cord injury by transplantation of bone marrow mesenchymal-stem cell-derived neurons. Chin Med J (Engl) 2005 118 : 1533 41.
2. Deng YB, Liu XG, Liu ZG, Liu XL, Liu Y, Zhou GQ. Implantation of BM mesenchymal stem cells into injured spinal cord elicits de novo neurogenesis and functional recovery: evidence from a study in rhesus monkeys. Cytotherapy 2006 8 : 210 4.
3. Urdzikova L, Jendelova P, Glogarova K, Burian M, Hajek M, Sykova E. Transplantation of bone marrow stem cells as well as mobilization by granulocyte-colony stimulating factor promotes recovery after spinal cord injury in rats. J Neurotrauma 2006 23 : 1379 91.
4. Pincus DW, Keyoung HM, Harrison-Restelli C, Goodman RR, Fraser RA, Edgar M, et al. Fibroblast growth factor-2/brain-derived neurotrophic factor-associated maturation of new neurons generated from adult human subependymal cells. Ann Neurol 1998 43 : 576 85.
5. Vescovi AL, Snyder EY. Establishment and properties of neural stem cell clones: plasticity in vitro and in vivo. Brain Pathol 1999 9 : 569 98.
6. Zompa EA, Cain LD, Everhart AW, Moyer MP, Hulsebosch CE. Transplant therapy: recovery of function after spinal cord injury. J Neurotrauma 1997 14 : 479 506.
7. Park KI, Liu S, Flax JD, Nissim S, Stieg PE, Snyder EY. Transplantation of neural progenitor and stem cells: developmental insights may suggest new therapies for spinal cord and other CNS dysfunction. J Neurotrauma 1999 16 : 675 87.
8. Fricker-Gates RA, Winkler C, Kirik D, Rosenblad C, Carpenter MK, Bjorklund A. EGF infusion stimulates the proliferation and migration of embryonic progenitor cells transplanted in the adult rat striatum. Exp Neurol 2000 165 : 237 47.
9. Studer L, Tabar V, McKay RD. Transplantation of expanded mesencephalic precursors leads to recovery in Parkinsonian rats. Nat Neurosci 1998 1 : 290 5.
10. Svendsen CN, Clarke DJ, Rosser AE, Dunnett SB. Survival and differentiation of rat and human epidermal growth factor-responsive precursor cells following grafting into the lesioned adult central nervous system. Exp Neurol 1996 137 : 376 88.
11. Coyne TM, Marcus AJ, Woodbury D, Black IB. Marrow stromal cells transplanted to the adult brain are rejected by an inflammatory response and transfer donor labels to host neurons and glia. Stem Cells 2006 24 : 2483 92.
12. Lei XL, Chiou GC. Studies on cardiovascular actions of Salvia miltiorrhiza. Am J Chin Med 1986 14 : 26 32.
13. Lay IS, Hsieh CC, Chiu JH, Shiao MS, Lui WY, Wu CW. Salvianolic acid B enhances in vitro angiogenesis and improves skin flap survival in Sprague-Dawley rats. J Surg Res 2003 115 : 279 85.
14. Chen YH, Lin SJ, Ku HH, Shiao MS, Lin FY, Chen JW, et al. Salvianolic acid B attenuates VCAM-1 and ICAM-1 expression in TNF-alpha-treated human aortic endothelial cells. J Cell Biochem 2001 82 : 512 21.
15. Chen YH, Du GH, Zhang JT. Salvianolic acid B protects brain against injuries caused by ischemia-reperfusion in rats. Acta Pharmacol Sin 2000 21 : 463 6.
16. Du GH, Qiu Y, Zhang JT. Salvianolic acid B protects the memory functions against transient cerebral ischemia in mice. J Asian Nat Prod Res 2000 2 : 145 52.
17. Tang M, Feng W, Zhang Y, Zhong J, Zhang J. Salvianolic acid B improves motor function after cerebral ischemia in rats. Behav Pharmacol 2006 17 : 493 8.
18. Nagaya N, Fujii T, Iwase T, Ohgushi H, Itoh T, Uematsu M, et al. Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis. Am J Physiol Heart Circ Physiol 2004 287 : H2670 6.
19. Basso DM, Beattie MS, Bresnahan JC. A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma 1995 12 : 1 21.
20. Mulligan MS, Varani J, Dame MK, Lane CL, Smith CW, Anderson DC, et al. Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats. J Clin Invest 1991 88 : 1396 406.
21. Taoka Y, Okajima K. Spinal cord injury in the rat. Prog Neurobiol 1998 56 : 341 58.
22. Taoka Y, Okajima K, Uchiba M, Murakami K, Harada N, Johno M, et al. Activated protein C reduces the severity of compression-induced spinal cord injury in rats by inhibiting activation of leukocytes. Neurosci 1998 18 : 1393 8.
23. Tsuchiya D, Hong S, Matsumori Y, Kayama T, Swanson RA, Dillman WH, et al. Overexpression of rat heat shock protein 70 reduces neuronal injury after transient focal ischemia, transient global ischemia, or kainic acid-induced seizures. Neurosurgery 2003 53 : 1179 87.