Interferon-gamma and interleukin-4 expression during Fasciola gigantica primary infection in crossbred bovine calves as determined by real -time PCR

Veterinary Parasitology

Volumn 152, Issue 1-2, 2008, Pages 158-161

  Ingale, S L ^a   Singh, P ^a   Raina, O K ^a   Mehra, U R ^a   Verma, A K ^a   Gupta, S C ^a   Mulik, S V ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

Author keywords

Crossbred calves; Cytokine; Fasciola gigantica; IFN ; IL 4; Real time PCR

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 4;

ANIMAL MODEL; ARTICLE; CALF (BOVINE); CONTROLLED STUDY; EOSINOPHIL COUNT; FASCIOLA GIGANTICA; GENE EXPRESSION; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE; TREMATODIASIS;

ANIMALS; BASE SEQUENCE; CATTLE; CATTLE DISEASES; CROSSES, GENETIC; EOSINOPHILS; FASCIOLA; FASCIOLIASIS; GENE EXPRESSION; INTERFERON TYPE II; INTERLEUKIN-4; LEUKOCYTES, MONONUCLEAR; POLYMERASE CHAIN REACTION; RNA, HELMINTH; TIME FACTORS;

ANIMALIA; BOS INDICUS; BOS TAURUS; BOVINAE; FASCIOLA GIGANTICA;

EID: 38749108441     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetpar.2007.11.023     Document Type: Article

References (15)

1. Brown W., Woods V., Chitko-Mckown C., Hash S., and Rice-Ficht A. Interleukin-10 is expressed by bovine type 1, type 2 helper and unrestricted parasite-specific T-cell clones and inhibits proliferation of all three subsets in an accessory cell-dependent manner. Infect. Immun. 62 (1994) 4697-4708
2. Butterworth A.E. Cell-mediated damage to helminthes. Adv. Parasitol. 23 (1984) 143-235
3. Clery D.G., Torgerson P., and Mulcahy G. Immune responses of chronically infected adult cattle to Fasciola hepatica. Vet. Parasitol. 62 (1996) 71-82
4. Else K.J., Finkelman F.D., and Grencis R.K. Cytokine-mediated regulation of chronic intestinal helminth infection. J. Exp. Med. 179 (1994) 347-351
5. Goldsby R.A., Kindt T.J., and Osborne B.A. Kuby Immunology (2000), W.H. Freeman and Company, New York
6. Hansen D.S., Clery D.G., Estuningsih S.E., Widjajanti S., Partoutomo S., and Spithill T.W. Immune responses in Indonesian thin tail and Merino sheep during a primary infection with Fasciola gigantica: lack of a specific IgG2 antibody response is associated with increased resistance to infection in Indonesian sheep. Int. J. Parasitol. 29 (1999) 1027-1035
7. Hoyle D.V., and Taylor D.W. The immune response of regional lymph nodes during the early stages of Fasciola hepatica infection in cattle. Parasite Immunol. 25 (2003) 221-229
8. Hughes D.L. Fasciola and Fascioloides. In: Soulsby E.J. (Ed). Immune Responses in Parasitic Infection: Immunol, Immunopathol and Immunoprophylaxis, Treamatodes and Cestodes vol. 2 (1987), CRC Press, Boca Raton 94-114
9. Khalil S.S., Abou S.S., and Rashwan E.A. Production of pro-inflammatory cytokines (GM-CSFIL-8 and IL-6) by monocytes from fasciolosis patients. J. Egypt Soc. Parasitol. 20 (1999) 1007-1015
10. Molina E.C. Serum interferon gamma and interleukins-6 and -8 during infection with Fasciola gigantica in cattle and buffaloes. J. Vet. Sci. 6 2 (2005) 135-139
11. Moreau E., Chauvin A., and Boulard C. IFN-γ and IL-10 production by hepatic lymph node and peripheral blood lymphocytes in Fasciola hepatica infected sheep. Parasite 5 (1998) 307-315
12. Mulcahy G., and Dalton J.P. Cathepsin L proteinases as vaccines against infection with Fasciola hepatica (liver fluke) in ruminant. Res. Vet. Sci. 70 (2001) 83-86
13. Mulcahy G., Joyce P., and Dalton J.P. In: Dalton J.P. (Ed). Immunology of Fasciola hepatica Infection. Fasciolosis (1999), CAB International, Cambridge 341-366
14. Piedrafita D., Estuningsih E., Pleasance J., Prowse R., Raadsma H.W., Meeusen Els N.T., and Spithill T.W. Peritoneal lavage cells of Indonesian thin-tail sheep mediate antibody-dependent superoxide radical cytotoxicity in vitro against newly excysted juvenile Fasciola gigantica but not juvenile Fasciola hepatica. Infect. Immun. 75 4 (2007) 1954-1963
15. Waldvogel A.S., Lepage M.F., Zakher A., Reichel M.P., Eicher R., and Heussler V.T. Expression of interleukin-4, interleukin-4 splice variants and interferon-gamma mRNA in calves experimentally infected with Fasciola hepatica. Vet. Immunol. Immunopathol. 97 (2004) 53-63