Forensic analysis of carbohydrate-deficient transferrin (CDT) by HPLC-Statistics and extreme CDT values

Forensic Science International

Volumn 175, Issue 1, 2008, Pages 27-30

  Arndt, Torsten ^a   Guessregen, Brunhilde ^a   Hallermann, Dörte ^a   Nauck, Markus ^a   Terjung, Dirk ^a   Weckesser, Holger ^b  

^a Bioscientia Center for Human Genetics   (Germany)

^b Bundesagentur fur Arbeit   (Germany)

Author keywords

Abuse; Alcohol; Alcoholism; Carbohydrate deficient transferrin; CDT

Indexed keywords

CARBOHYDRATE DEFICIENT TRANSFERRIN;

ALCOHOL ABUSE; ARTICLE; FEMALE; FORENSIC IDENTIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOGRAM; HUMAN; MALE; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

EID: 38749104309     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.forsciint.2007.05.001     Document Type: Article

References (9)

1. Stibler H. Carbohydrate-deficient transferrin in serum: a new marker of potentially harmful alcohol consumption reviewed. Clin. Chem. 37 (1991) 2029-2037
2. Arndt T. Carbohydrate-deficient transferrin as a marker of chronic alcohol abuse: a critical review of preanalysis, analysis, and interpretation. Clin. Chem. 47 (2001) 13-27
3. Bortolotti F., de Paoli G., and Tagliaro F. Carbohydrate-deficient transferrin (CDT) as a marker of alcohol abuse: a critical review of the literature 2001-2005. J. Chromatogr. B 841 (2006) 96-109
4. Arndt T., Meier U., Nauck M., and Gressner A. Primary biliary cirrhosis is not a clinical condition for increased carbohydrate-deficient transferrin: experience with four independent CDT analysis methods. Clin. Chim. Acta 372 (2006) 184-187
5. Arndt T., Gressner A., Herwig J., Meier U., and Sewell A.C. Argininosuccinate lyase deficiency (ASL) and carbohydrate-deficient transferrin (CDT): Experience with four independent CDT analysis methods-misleading results given by the %CDT TIA assay. Clin. Chim. Acta 373 (2006) 117-120
6. Arndt T., Erkens M., Holtkamp K., Keller T., and Gressner A.M. High prevalence of increased trisialotransferrin concentrations in patients with anorexia nervosa: implications for determination of carbohydrate-deficient transferrin. Clin. Chim. Acta 379 (2007) 150-153
7. Jeppsson J.-O., Arndt T., Schellenberg F., Wielders J.P.M., Anton R.F., Whitfield J.B., and Helander A. International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Working Group on Standardization of Carbohydrate-deficient Transferrin. Toward standardization of carbohydrate-deficient transferrin (CDT) measurements: I. Analyte definition and proposal of a candidate reference method. Clin. Chem. Lab. Med. 45 (2007) 558-562
8. Arndt T. Valid carbohydrate-deficient transferrin testing. Clin. Chim. Acta 364 (2006) 367-368
9. Arndt T., and Keller T. Forensic analysis of carbohydrate-deficient transferrin (CDT): implementation of a screening and confirmatory analysis concept is hampered by the lack of CDT isoform standards. Forens. Sci. Int. 146 (2004) 9-16