Molecular Characterization of Two Homologs of the Caenorhabditis elegans Cadmium-Responsive Gene cdr-1: cdr-4 and cdr-6

Journal of Molecular Biology

Volumn 376, Issue 3, 2008, Pages 621-633

  Dong, Jie ^a   Boyd, Windy A ^b   Freedman, Jonathan H ^b  

^a DUKE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

C. elegans; cadmium; RNA interference; transcription; transition metal

Indexed keywords

ARSENIC; CADMIUM; MERCURY; MESSENGER RNA; ZINC;

ARTICLE; CAENORHABDITIS ELEGANS; DNA SEQUENCE; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE IDENTIFICATION; HYPOOSMOTIC STRESS; INTESTINE CELL; LIFESPAN; LYSOSOME; NEMATODE; NONHUMAN; OPEN READING FRAME; OSMOREGULATION; PARASITE DEVELOPMENT; PHARYNX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REPRODUCTION; RNA INTERFERENCE; SEQUENCE HOMOLOGY;

CAENORHABDITIS ELEGANS; NEMATODA;

EID: 38749096249     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.11.094     Document Type: Article

References (62)

1. Agency for Toxic Substances and Disease Registry. CERCLA Priority List of Hazardous Substances, Atlanta, GA (2006)
2. Waalkes M.P., Coogan T.P., and Barter R.A. Toxicological principles of metal carcinogenesis with special emphasis on cadmium. Crit. Rev. Toxicol. 22 (1992) 175-201
3. Stohs S.J., and Bagchi D. Oxidative mechanisms in the toxicity of metal ions. Free Radical Biol. Med. 18 (1995) 321-336
4. Koizumi T., and Li Z.G. Role of oxidative stress in single-dose, cadmium-induced testicular cancer. J. Toxicol. Environ. Health 37 (1992) 25-36
5. Broeks A., Gerrard B., Allikmets R., Dean M., and Plasterk R.H. Homologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegans. EMBO J. 15 (1996) 6132-6143
6. Endo T. Transport of cadmium across the apical membrane of epithelial cell lines. Comp. Biochem. Physiol., Part C: Toxicol. Pharmacol. 131 (2002) 223-229
7. Havelaar A.C., de Gast I.L., Snijders S., Beerens C.E., Mancini G.M., and Verheijen F.W. Characterization of a heavy metal ion transporter in the lysosomal membrane. FEBS Lett. 436 (1998) 223-227
8. Paulsen I.T., and Saier Jr. M.H. A novel family of ubiquitous heavy metal ion transport proteins. J. Membr. Biol. 156 (1997) 99-103
9. Kagi J.H., and Schaffer A. Biochemistry of metallothionein. Biochemistry 27 (1988) 8509-8515
10. Hartwig A., and Schwerdtle T. Interactions by carcinogenic metal compounds with DNA repair processes: toxicological implications. Toxicol. Lett. 127 (2002) 47-54
11. Jungmann J., Reins H.A., Schobert C., and Jentsch S. Resistance to cadmium mediated by ubiquitin-dependent proteolysis. Nature 361 (1993) 369-371
12. Lee M.J., Nishio H., Ayaki H., Yamamoto M., and Sumino K. Upregulation of stress response mRNAs in COS-7 cells exposed to cadmium. Toxicology 174 (2002) 109-117
13. Gupta S., Athar M., Behari J.R., and Srivastava R.C. Cadmium-mediated induction of cellular defence mechanism: a novel example for the development of adaptive response against a toxicant. Ind. Health 29 (1991) 1-9
14. Kostic M.M., Ognjanovic B., Dimitrijevic S., Zikic R.V., Stajn A., Rosic G.L., and Zivkovic R.V. Cadmium-induced changes of antioxidant and metabolic status in red blood cells of rats: in vivo effects. Eur. J. Haematol. 51 (1993) 86-92
15. Tan Y., Shi L., Hussain S.M., Xu J., Tong W., Frazier J.M., and Wang C. Integrating time-course microarray gene expression profiles with cytotoxicity for identification of biomarkers in primary rat hepatocytes exposed to cadmium. Bioinformatics 22 (2006) 77-87
16. Zhou T., Jia X., Chapin R.E., Maronpot R.R., Harris M.W., Liu J., et al. Cadmium at a non-toxic dose alters gene expression in mouse testes. Toxicol. Lett. 154 (2004) 191-200
17. Regunathan A., Glesne D.A., Wilson A.K., Song J., Nicolae D., Flores T., and Bhattacharyya M.H. Microarray analysis of changes in bone cell gene expression early after cadmium gavage in mice. Toxicol. Appl. Pharmacol. 191 (2003) 272-293
18. Yamada H., and Koizumi S. DNA microarray analysis of human gene expression induced by a non-lethal dose of cadmium. Ind. Health 40 (2002) 159-166
19. Cui Y., McBride S.J., Boyd W.A., Alper S., and Freedman J.H. Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity. Genome Biol. 8 (2007) R122
20. Liao V.H., Dong J., and Freedman J.H. Molecular characterization of a novel, cadmium-inducible gene from the nematode Caenorhabditis elegans. A new gene that contributes to the resistance to cadmium toxicity. J. Biol. Chem. 277 (2002) 42049-42059
21. Altschul S.F., Gish W., Miller W., Myers E.W., and Lipman D.J. Basic local alignment search tool. J. Mol. Biol. 215 (1990) 403-410
22. Altschul S.F., Madden T.L., Schaffer A.A., Zhang J., Zhang Z., Miller W., and Lipman D.J. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25 (1997) 3389-3402
23. Dong J., Song M.O., and Freedman J.H. Identification and characterization of a family of Caenorhabditis elegans genes that is homologous to the cadmium-responsive gene cdr-1. Biochim. Biophys. Acta 1727 (2005) 16-26
24. Sigrist C.J., Cerutti L., Hulo N., Gattiker A., Falquet L., Pagni M., et al. PROSITE: a documented database using patterns and profiles as motif descriptors. Brief. Bioinform. 3 (2002) 265-274
25. Tully D.B., Collins B.J., Overstreet J.D., Smith C.S., Dinse G.E., Mumtaz M.M., and Chapin R.E. Effects of arsenic, cadmium, chromium, and lead on gene expression regulated by a battery of 13 different promoters in recombinant HepG2 cells. Toxicol. Appl. Pharmacol. 168 (2000) 79-90
26. Alam J. Multiple elements within the 5′ distal enhancer of the mouse heme oxygenase-1 gene mediate induction by heavy metals. J. Biol. Chem. 269 (1994) 25049-25056
27. Williams G.T., and Morimoto R.I. Maximal stress-induced transcription from the human HSP70 promoter requires interactions with the basal promoter elements independent of rotational alignment. Mol. Cell. Biol. 10 (1990) 3125-3136
28. 2+/calmodulin-dependent protein kinase cascade in Caenorhabditis elegans. Implication in transcriptional activation. J. Biol. Chem. 274 (1999) 22556-22562
29. Hahn J.S., Hu Z., Thiele D.J., and Iyer V.R. Genome-wide analysis of the biology of stress responses through heat shock transcription factor. Mol. Cell. Biol. 24 (2004) 5249-5256
30. Britton C., McKerrow J.H., and Johnstone I.L. Regulation of the Caenorhabditis elegans gut cysteine protease gene cpr-1: requirement for GATA motifs. J. Mol. Biol. 283 (1998) 15-27
31. Moilanen L.H., Fukushige T., and Freedman J.H. Regulation of metallothionein gene transcription. Identification of upstream regulatory elements and transcription factors responsible for cell-specific expression of the metallothionein genes from Caenorhabditis elegans. J. Biol. Chem. 274 (1999) 29655-29665
32. Simon M.C. Gotta have GATA. Nat. Genet. 11 (1995) 9-11
33. Freedman J.H., Slice L.W., Dixon D., Fire A., and Rubin C.S. The novel metallothionein genes of Caenorhabditis elegans. Structural organization and inducible, cell-specific expression. J. Biol. Chem. 268 (1993) 2554-2564
34. White J. The anatomy. In: Wood W.B. (Ed). The Nematode Caenorhabditis elegans (1985), Cold Spring Harbor Press, Cold Spring Harbor, NY 81-122
35. Clokey G.V., and Jacobson L.A. The autofluorescent "lipofuscin granules" in the intestinal cells of Caenorhabditis elegans are secondary lysosomes. Mech. Ageing Dev. 35 (1986) 79-94
36. Cioci L.K., Qiu L., and Freedman J.H. Transgenic strains of the nematode Caenorhabditis elegans as biomonitors of metal contamination. Environ. Toxicol. Chem. 19 (2000) 2122-2129
37. Jeong E.M., Moon C.H., Kim C.S., Lee S.H., Baik E.J., Moon C.K., and Jung Y.S. Cadmium stimulates the expression of ICAM-1 via NF-kappaB activation in cerebrovascular endothelial cells. Biochem. Biophys. Res. Commun. 320 (2004) 887-892
38. Liu R.Y., Corry P.M., and Lee Y.J. Potential involvement of a constitutive heat shock element binding factor in the regulation of chemical stress-induced hsp70 gene expression. Mol. Cell. Biochem. 144 (1995) 27-34
39. Alam J., Wicks C., Stewart D., Gong P., Touchard C., Otterbein S., et al. Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor. J. Biol. Chem. 275 (2000) 27694-27702
40. Hung J.J., Cheng T.J., Lai Y.K., and Chang M.D. Differential activation of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinases confers cadmium-induced HSP70 expression in 9L rat brain tumor cells. J. Biol. Chem. 273 (1998) 31924-31931
41. Saydam N., Steiner F., Georgiev O., and Schaffner W. Heat and heavy metal stress synergize to mediate transcriptional hyperactivation by metal-responsive transcription factor MTF-1. J. Biol. Chem. 278 (2003) 31879-31883
42. Spieth J., and Blumenthal T. The Caenorhabditis elegans vitellogenin gene family includes a gene encoding a distantly related protein. Mol. Cell. Biol. 5 (1985) 2495-2501
43. Kennedy B.P., Aamodt E.J., Allen F.L., Chung M.A., Heschl M.F., and McGhee J.D. The gut esterase gene (ges-1) from the nematodes Caenorhabditis elegans and Caenorhabditis briggsae. J. Mol. Biol. 229 (1993) 890-908
44. Hawkins M.G., and McGhee J.D. elt-2, a second GATA factor from the nematode Caenorhabditis elegans. J. Biol. Chem. 270 (1995) 14666-14671
45. Egan C.R., Chung M.A., Allen F.L., Heschl M.F., Van Buskirk C.L., and McGhee J.D. A gut-to-pharynx/tail switch in embryonic expression of the Caenorhabditis elegans ges-1 gene centers on two GATA sequences. Dev. Biol. 170 (1995) 397-419
46. MacMorris M., Broverman S., Greenspoon S., Lea K., Madej C., Blumenthal T., and Spieth J. Regulation of vitellogenin gene expression in transgenic Caenorhabditis elegans: short sequences required for activation of the vit-2 promoter. Mol. Cell. Biol. 12 (1992) 1652-1662
47. Fukushige T., Hawkins M.G., and McGhee J.D. The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine. Dev. Biol. 198 (1998) 286-302
48. Aamodt E.J., Chung M.A., and McGhee J.D. Spatial control of gut-specific gene expression during Caenorhabditis elegans development. Science 252 (1991) 579-582
49. Evans T. Regulation of cardiac gene expression by GATA-4/5/6. Trends Cardiovasc. Med. 7 (1997) 75-83
50. Albertson D.G., and Thomson J.N. The pharynx of Caenorhabditis elegans. Philos. Trans. R. Soc. Lond., B Biol. Sci. 275 (1976) 299-325
51. Hall D.H., and Altun Z.F. Atlas of C. elegans Anatomy-An Illustrated Handbook (2004). http://www.wormatlas.org/handbook/contents.htm http://www.wormatlas.org/handbook/contents.htm
52. Nelson F.K., and Riddle D.L. Functional study of the Caenorhabditis elegans secretory-excretory system using laser microsurgery. J. Exp. Zool. 231 (1984) 45-56
53. Huang P., and Stern M.J. FGF signaling functions in the hypodermis to regulate fluid balance in C. elegans. Development 131 (2004) 2595-2604
54. WormBase Release WS160. (2006).
55. Brenner S. The genetics of Caenorhabditis elegans. Genetics 77 (1974) 71-94
56. Stringham E.G., and Candido E.P.M. Transgenic hsp16-lacZ strains of the soil nematode Caenorhabditis elegans as biological monitors of environmental stress. Environ. Toxicol. Chem. 13 (1994) 1211-1220
57. Cummins C., and Anderson P. Regulatory myosin light-chain genes of Caenorhabditis elegans. Mol. Cell. Biol. 8 (1988) 5339-5349
58. Mello C., and Fire A. DNA transformation. Methods Cell Biol. 48 (1995) 451-482
59. Timmons L., and Fire A. Specific interference by ingested dsRNA. Nature 395 (1998) 854
60. Timmons L., Court D.L., and Fire A. Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 263 (2001) 103-112
61. Kamath R.S., Martinez-Campos M., Zipperlen P., Fraser A.G., and Ahringer J. Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol. 2 (2001) RESEARCH0002
62. Pulak R. Techniques for analysis, sorting, and dispensing of C. elegans on the COPAS flow-sorting system. Methods Mol. Biol. 351 (2006) 275-286