Compensatory evolution of a WW domain variant lacking the strictly conserved Trp residue

Journal of Molecular Evolution

Volumn 66, Issue 1, 2008, Pages 61-71

  Yanagida, Hayato ^a   Matsuura, Tomoaki ^a,b   Yomo, Tetsuya ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Compensatory mutation; Conserved residue; Directed evolution; Divergent evolution; Ribosome display; Second site revertant; Unfolded protein; WW domain

Indexed keywords

AMINO ACID; PROLINE; TRANSIENT RECEPTOR POTENTIAL CHANNEL;

ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENE SEQUENCE; GENETIC VARIABILITY; NONHUMAN; PROTEIN STRUCTURE; SURFACE PLASMON RESONANCE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; DIRECTED MOLECULAR EVOLUTION; EVOLUTION, MOLECULAR; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTEINS; TRYPTOPHAN; VARIATION (GENETICS);

EID: 38649143198     PISSN: 00222844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00239-007-9061-5     Document Type: Article

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