A pilot study of oral bioavailability of dioxins and furans from contaminated soils: Impact of differential hepatic enzyme activity and species differences

Chemosphere

Volumn 70, Issue 10, 2008, Pages 1774-1786

  Budinsky, R A ^a   Rowlands, J C ^a   Casteel, S ^b   Fent, G ^b   Cushing, C A ^c   Newsted, J ^d   Giesy, J P ^e   Ruby, M V ^f   Aylward, L L ^a  

^a DOW CHEMICAL COMPANY   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c EXPONENT INC   (United States)

^d ENTRIX INC   (United States)

^e UNIVERSITY OF SASKATCHEWAN   (Canada)

^f LLP ^*

Author keywords

Bioavailability; Dioxin; Furans; Rats; Soils; Swine

Indexed keywords

BIOAVAILABILITY; DIOXIN; FURANS; SWINE;

BIODIVERSITY; CONTAMINATION; ENZYMES; FURAN RESINS; RISK ASSESSMENT; SOILS;

HYDROCARBONS;

CORN OIL; DIOXIN; FURAN; LIVER ENZYME; POLYCHLORINATED DIBENZODIOXIN; POLYCHLORINATED DIBENZOFURAN; TETRACHLORODIBENZOFURAN; UNCLASSIFIED DRUG;

BIODIVERSITY; CONTAMINATION; ENZYMES; FURAN RESINS; HYDROCARBONS; RISK ASSESSMENT; SOILS;

BIOAVAILABILITY; COMPARATIVE STUDY; DOSE-RESPONSE RELATIONSHIP; ENZYME ACTIVITY; ESTIMATION METHOD; JUVENILE; PCDD; PCDF; RISK ASSESSMENT; RODENT; SOIL POLLUTION; UNGULATE;

ANIMAL EXPERIMENT; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; EXPERIMENTAL DESIGN; FEEDING; FEMALE; FOLLOW UP; NONHUMAN; PILOT STUDY; RAT; RISK ASSESSMENT; SOIL POLLUTION; SPECIES DIFFERENCE;

ANIMALS; BENZOFURANS; BIOLOGICAL AVAILABILITY; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; MICROSOMES, LIVER; OXIDOREDUCTASES; PARTICLE SIZE; PILOT PROJECTS; RATS; RATS, SPRAGUE-DAWLEY; SOIL POLLUTANTS; SPECIES SPECIFICITY; SWINE; TETRACHLORODIBENZODIOXIN;

ANIMALIA; RATTUS; SUIDAE; ZEA MAYS;

EID: 38649143176     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2007.08.035     Document Type: Article

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