메뉴 건너뛰기




Volumn 32, Issue 11, 2007, Pages 937-942

Albinterferon alfa-2b. Immunomodulator treatment of hepatitis C virus

Author keywords

[No Author keywords available]

Indexed keywords

ALBINTERFERON ALPHA 2B; ALBUMIN ALPHA INTERFERON; ALPHA INTERFERON; ALPHA2B INTERFERON; BELEROFON; HCV INTERFERON ENHANCING THERAPY; HUMAN LEUCOCYTE INTERFERON ALFA; INTERFERON; INTERFERON ALPHA 2B XL; INTERFERON ALPHA 8; NATURAL HUMAN MULTISUBTYPE INTERFERON ALPHA; OMEGA INTERFERON; PEG INTERFERON LAMBDA; PEGINTERFERON; R 7025; RIBAVIRIN; UNCLASSIFIED DRUG;

EID: 38649142444     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: 10.1358/dof.2007.032.11.1149301     Document Type: Article
Times cited : (1)

References (30)
  • 1
    • 38649133060 scopus 로고    scopus 로고
    • Prous Science Disease Briefings: Hepatitis C (online publication). Updated 2007.
    • Prous Science Disease Briefings: Hepatitis C (online publication). Updated 2007.
  • 2
    • 23944506014 scopus 로고    scopus 로고
    • Global epidemiology of hepatitis C virus infection
    • Shepard, C.W. et al. Global epidemiology of hepatitis C virus infection. Lancet Infect Dis 2005, 5(9): 558-67.
    • (2005) Lancet Infect Dis , vol.5 , Issue.9 , pp. 558-567
    • Shepard, C.W.1
  • 3
    • 0037979127 scopus 로고    scopus 로고
    • Chronic hepatitis C virus infection
    • Flamm, S.L. Chronic hepatitis C virus infection. JAMA - J Am Med Assoc 2003, 289(18): 2413-7.
    • (2003) JAMA - J Am Med Assoc , vol.289 , Issue.18 , pp. 2413-2417
    • Flamm, S.L.1
  • 4
    • 16244391099 scopus 로고    scopus 로고
    • Impact of hepatitis C on health related quality of life: A systematic review and quantitative assessment
    • Spiegel, B.M., Younossi, Z.M., Hays, R.D, Revicki, D., Robbins, S., Kanwal, F. Impact of hepatitis C on health related quality of life: A systematic review and quantitative assessment. Hepatology 2005, 41(4): 790-800.
    • (2005) Hepatology , vol.41 , Issue.4 , pp. 790-800
    • Spiegel, B.M.1    Younossi, Z.M.2    Hays, R.D.3    Revicki, D.4    Robbins, S.5    Kanwal, F.6
  • 5
    • 0035150725 scopus 로고    scopus 로고
    • Viral, host and interferon-related factors modulating the effect of interferon therapy for hepatitis C virus infection
    • Hu, K.Q., Vierling, J.M., Redeker, A.G. Viral, host and interferon-related factors modulating the effect of interferon therapy for hepatitis C virus infection. J Viral Hepat 2001, 8(1): 1-18.
    • (2001) J Viral Hepat , vol.8 , Issue.1 , pp. 1-18
    • Hu, K.Q.1    Vierling, J.M.2    Redeker, A.G.3
  • 6
    • 4444344991 scopus 로고    scopus 로고
    • Development and pharmacokinetics and pharmacodynamics of pegylated interferon alfa-2a (50 kD)
    • Reddy, K.R. Development and pharmacokinetics and pharmacodynamics of pegylated interferon alfa-2a (50 kD). Semin Liver Dis 2004, 24(Suppl. 2): 33-8.
    • (2004) Semin Liver Dis , vol.24 , Issue.SUPPL. 2 , pp. 33-38
    • Reddy, K.R.1
  • 7
    • 0032547938 scopus 로고    scopus 로고
    • Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C
    • McHutchison, J.G., Gordon, S.C., Schiff, E.R. et al. Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. N Engl J Med 1998, 339(21): 1485-92.
    • (1998) N Engl J Med , vol.339 , Issue.21 , pp. 1485-1492
    • McHutchison, J.G.1    Gordon, S.C.2    Schiff, E.R.3
  • 8
    • 0032585237 scopus 로고    scopus 로고
    • Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus
    • Poynard, T., Marcellin, P., Lee, S.S. et al. Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. Lancet 1998, 352(9138): 1426-32.
    • (1998) Lancet , vol.352 , Issue.9138 , pp. 1426-1432
    • Poynard, T.1    Marcellin, P.2    Lee, S.S.3
  • 9
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
    • Fried, M.W., Shiffman, M.L., Reddy, K.R. et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002, 347(13): 975-82.
    • (2002) N Engl J Med , vol.347 , Issue.13 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3
  • 10
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomized trial
    • Manns, M.P., McHutchison, J.G., Gordon, S.C. et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomized trial. Lancet 2001, 358(9286): 958-65.
    • (2001) Lancet , vol.358 , Issue.9286 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3
  • 11
    • 0036788338 scopus 로고    scopus 로고
    • Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C
    • McHutchison, J.G., Manns, M., Patel, K. et al. Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C. Gastroenterology 2002, 123: 1061-9.
    • (2002) Gastroenterology , vol.123 , pp. 1061-1069
    • McHutchison, J.G.1    Manns, M.2    Patel, K.3
  • 12
    • 0036827834 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic studies of a human serum albumin-interferon-α fusion protein in cynomolgus monkeys
    • Osborn, B.L., Olsen, H.S., Nardelli, B. et al. Pharmacokinetic and pharmacodynamic studies of a human serum albumin-interferon-α fusion protein in cynomolgus monkeys. J Pharmacol Exp Ther 2002, 303(2): 540-8.
    • (2002) J Pharmacol Exp Ther , vol.303 , Issue.2 , pp. 540-548
    • Osborn, B.L.1    Olsen, H.S.2    Nardelli, B.3
  • 13
    • 0037225719 scopus 로고    scopus 로고
    • An IFN-β-albumin fusion protein that displays improved pharmacokinetic and pharmacodynamic properties in nonhuman primates
    • Sung, C., Nardelli, B., Lafleur, D.W. et al. An IFN-β-albumin fusion protein that displays improved pharmacokinetic and pharmacodynamic properties in nonhuman primates. J Interferon Cytokine Res 2003, 23(1): 25-36.
    • (2003) J Interferon Cytokine Res , vol.23 , Issue.1 , pp. 25-36
    • Sung, C.1    Nardelli, B.2    Lafleur, D.W.3
  • 14
    • 33747742768 scopus 로고    scopus 로고
    • Albuferon exhibits efficient anti-HCV activity in cell culture
    • May 14-19, Chicago, Abst S920
    • Liu, C., Zhu, H., Eylar, J. et al. Albuferon exhibits efficient anti-HCV activity in cell culture. Dig Dis Week (May 14-19, Chicago) 2005, Abst S920.
    • (2005) Dig Dis Week
    • Liu, C.1    Zhu, H.2    Eylar, J.3
  • 15
    • 38649142657 scopus 로고    scopus 로고
    • Moore, P., Sidwell, R., Paragas, J., Osborn, B., Nardelli, B., Freimuth, W., Subramanian, M. Albuferon - A novel therapeutic agent with potent in vitro activity against RNA viral agents of bioterrorism. 2nd Annu ASM Biodefense Emerging Dis Res Meet (March 7-10, Baltimore) 2004, Abst 171(G).
    • Moore, P., Sidwell, R., Paragas, J., Osborn, B., Nardelli, B., Freimuth, W., Subramanian, M. Albuferon - A novel therapeutic agent with potent in vitro activity against RNA viral agents of bioterrorism. 2nd Annu ASM Biodefense Emerging Dis Res Meet (March 7-10, Baltimore) 2004, Abst 171(G).
  • 16
    • 38649119017 scopus 로고    scopus 로고
    • Moore, P., Paragas, J., Hogan, R. et al. Albuferon beta shows potent in vitro activity against Ebola and the SARS virus. 2nd Annu ASM Biodefense Emerging Dis Res Meet (March 7-10, Baltimore) 2004, Abst 172(G).
    • Moore, P., Paragas, J., Hogan, R. et al. Albuferon beta shows potent in vitro activity against Ebola and the SARS virus. 2nd Annu ASM Biodefense Emerging Dis Res Meet (March 7-10, Baltimore) 2004, Abst 172(G).
  • 18
    • 33644551889 scopus 로고    scopus 로고
    • A phase I/II study evaluating escalating doses of recombinant human albumin-interferon-α fusion protein in chronic hepatitis C patients who have failed previous interferon-α-based therapy
    • Balan, V., Nelson, D.R., Sulkowski, M.S. et al. A phase I/II study evaluating escalating doses of recombinant human albumin-interferon-α fusion protein in chronic hepatitis C patients who have failed previous interferon-α-based therapy. Antiviral Ther 2006, 11(1): 35-45.
    • (2006) Antiviral Ther , vol.11 , Issue.1 , pp. 35-45
    • Balan, V.1    Nelson, D.R.2    Sulkowski, M.S.3
  • 19
    • 33644918919 scopus 로고    scopus 로고
    • A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients
    • Bain, V.G., Kaita, K.D., Yoshida, E.M. et al. A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients. J Hepatology 2006, 44(4): 671-8.
    • (2006) J Hepatology , vol.44 , Issue.4 , pp. 671-678
    • Bain, V.G.1    Kaita, K.D.2    Yoshida, E.M.3
  • 20
    • 38649133059 scopus 로고    scopus 로고
    • Favorable pharmacokinetics of albumin interferon alfa-2b in subjects with chronic hepatitis C
    • AASLD, Oct 27-31, Boston, Abst 1140
    • Fiscella, M., Balan, V., Nelson, D. et al. Favorable pharmacokinetics of albumin interferon alfa-2b in subjects with chronic hepatitis C. 57th Annu Meet Am Assoc Study Liver Dis (AASLD) (Oct 27-31, Boston) 2006, Abst 1140.
    • (2006) 57th Annu Meet Am Assoc Study Liver Dis
    • Fiscella, M.1    Balan, V.2    Nelson, D.3
  • 21
    • 38649105032 scopus 로고    scopus 로고
    • Modulation of interferon specific gene expression by Albuferon(TM) in subjects with chronic hepatitis C and correlation with anti-viral response
    • April 13-17, Paris, Abst 447
    • Moore, P., Balan, V., Nelson, D. et al. Modulation of interferon specific gene expression by Albuferon(TM) in subjects with chronic hepatitis C and correlation with anti-viral response. 40th Annu Meet Eur Assoc Study Liver (EASL) (April 13-17, Paris) 2005, Abst 447.
    • (2005) 40th Annu Meet Eur Assoc Study Liver (EASL)
    • Moore, P.1    Balan, V.2    Nelson, D.3
  • 22
    • 35748955193 scopus 로고    scopus 로고
    • Comparable antiviral response rates with albumin interferon alfa-2b doses at q2w or q4w intervals in naive subjects with genotype 2 or 3 chronic hepatitis C
    • April 11-15, Barcelona, Abst 9
    • Bain, V.G., Marotta, P., Kaita, K. et al. Comparable antiviral response rates with albumin interferon alfa-2b doses at q2w or q4w intervals in naive subjects with genotype 2 or 3 chronic hepatitis C. J Heptol [42nd Annu Meet Eur Assoc Study Liver (EASL) (April 11-15, Barcelona) 2007] 2007, 46(Suppl. 1): Abst 9.
    • (2007) J Heptol [42nd Annu Meet Eur Assoc Study Liver (EASL) , vol.46 , Issue.SUPPL. 1
    • Bain, V.G.1    Marotta, P.2    Kaita, K.3
  • 23
    • 38649125763 scopus 로고    scopus 로고
    • A phase 2 dose-escalation study of albuferon combined with ribavirin in nonresponders to prior interferon based therapy for chronic hepatitis C infection
    • April 26-30, Vienna, Abst 113
    • Rustgi, V., Nelson, D., Balan, V. et al. A phase 2 dose-escalation study of albuferon combined with ribavirin in nonresponders to prior interferon based therapy for chronic hepatitis C infection. 41st Annu Meet Eur Assoc Study Liver (EASL) (April 26-30, Vienna) 2006, Abst 113.
    • (2006) 41st Annu Meet Eur Assoc Study Liver (EASL)
    • Rustgi, V.1    Nelson, D.2    Balan, V.3
  • 24
    • 38649114548 scopus 로고    scopus 로고
    • Albumin interferon alfa-2b dosed at q2w or q4w interval demonstrates comparable week 12 efficacy response in IFN naive, genotype-1 rapid viral responders
    • April 11-15, Barcelona, Abst 624
    • Neumann, A.U., Rozenberg, L., Zeuzem, S. et al. Albumin interferon alfa-2b dosed at q2w or q4w interval demonstrates comparable week 12 efficacy response in IFN naive, genotype-1 rapid viral responders. J Hepatol [42nd Annu Meet Eur Assoc Study Liver (EASL) (April 11-15, Barcelona) 2007] 2007, 46(Suppl. 1): Abst 624.
    • (2007) J Hepatol [42nd Annu Meet Eur Assoc Study Liver (EASL) , vol.46 , Issue.SUPPL. 1
    • Neumann, A.U.1    Rozenberg, L.2    Zeuzem, S.3
  • 25
    • 35748968163 scopus 로고    scopus 로고
    • Antiviral response at week 12 following completion of treatment with albinterferon alpha-2b plus ribavirin in genotype 1, IFN-naive, chronic hepatitis C patients
    • April 11-15, Barcelona, Abst 779
    • Zeuzem, S., Benhamou, Y., Bain, V. et al. Antiviral response at week 12 following completion of treatment with albinterferon alpha-2b plus ribavirin in genotype 1, IFN-naive, chronic hepatitis C patients. J Hepatol [42nd Annu Meet Eur Assoc Study Liver (EASL) (April 11-15, Barcelona) 2007], 2007, Abst 779.
    • (2007) J Hepatol [42nd Annu Meet Eur Assoc Study Liver (EASL)
    • Zeuzem, S.1    Benhamou, Y.2    Bain, V.3
  • 26
    • 38649110015 scopus 로고    scopus 로고
    • Interim (week 12) phase 2B virological efficacy and safety results of albumin interferon alfa-2b combined with ribavirin in genotype 1 chronic hepatitis C infection
    • April 26-30, Vienna, Abst 733
    • Zeuzem, S., Benhamou, Y., Shouval, D. et al. Interim (week 12) phase 2B virological efficacy and safety results of albumin interferon alfa-2b combined with ribavirin in genotype 1 chronic hepatitis C infection. 41st Annu Meet Eur Assoc Study Liver (EASL) (April 26-30, Vienna) 2006, Abst 733.
    • (2006) 41st Annu Meet Eur Assoc Study Liver (EASL)
    • Zeuzem, S.1    Benhamou, Y.2    Shouval, D.3
  • 27
    • 38649111842 scopus 로고    scopus 로고
    • Interim antiviral and safety data with albumin interferon alfa-2b combined with ribavirin in a phase 2b study conducted in a genotype 1, IFN-naive, chronic hepatitis C population
    • Oct 27-31, Boston, Abst 1141
    • McHutchison, J., Zeuzem, S., Benhamou, Y. et al. Interim antiviral and safety data with albumin interferon alfa-2b combined with ribavirin in a phase 2b study conducted in a genotype 1, IFN-naive, chronic hepatitis C population. 57th Annu Meet Am Assoc Study Liver Dis (Oct 27-31, Boston) 2006, Abst 1141.
    • (2006) 57th Annu Meet Am Assoc Study Liver Dis
    • McHutchison, J.1    Zeuzem, S.2    Benhamou, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.