-
1
-
-
38649133060
-
-
Prous Science Disease Briefings: Hepatitis C (online publication). Updated 2007.
-
Prous Science Disease Briefings: Hepatitis C (online publication). Updated 2007.
-
-
-
-
2
-
-
23944506014
-
Global epidemiology of hepatitis C virus infection
-
Shepard, C.W. et al. Global epidemiology of hepatitis C virus infection. Lancet Infect Dis 2005, 5(9): 558-67.
-
(2005)
Lancet Infect Dis
, vol.5
, Issue.9
, pp. 558-567
-
-
Shepard, C.W.1
-
3
-
-
0037979127
-
Chronic hepatitis C virus infection
-
Flamm, S.L. Chronic hepatitis C virus infection. JAMA - J Am Med Assoc 2003, 289(18): 2413-7.
-
(2003)
JAMA - J Am Med Assoc
, vol.289
, Issue.18
, pp. 2413-2417
-
-
Flamm, S.L.1
-
4
-
-
16244391099
-
Impact of hepatitis C on health related quality of life: A systematic review and quantitative assessment
-
Spiegel, B.M., Younossi, Z.M., Hays, R.D, Revicki, D., Robbins, S., Kanwal, F. Impact of hepatitis C on health related quality of life: A systematic review and quantitative assessment. Hepatology 2005, 41(4): 790-800.
-
(2005)
Hepatology
, vol.41
, Issue.4
, pp. 790-800
-
-
Spiegel, B.M.1
Younossi, Z.M.2
Hays, R.D.3
Revicki, D.4
Robbins, S.5
Kanwal, F.6
-
5
-
-
0035150725
-
Viral, host and interferon-related factors modulating the effect of interferon therapy for hepatitis C virus infection
-
Hu, K.Q., Vierling, J.M., Redeker, A.G. Viral, host and interferon-related factors modulating the effect of interferon therapy for hepatitis C virus infection. J Viral Hepat 2001, 8(1): 1-18.
-
(2001)
J Viral Hepat
, vol.8
, Issue.1
, pp. 1-18
-
-
Hu, K.Q.1
Vierling, J.M.2
Redeker, A.G.3
-
6
-
-
4444344991
-
Development and pharmacokinetics and pharmacodynamics of pegylated interferon alfa-2a (50 kD)
-
Reddy, K.R. Development and pharmacokinetics and pharmacodynamics of pegylated interferon alfa-2a (50 kD). Semin Liver Dis 2004, 24(Suppl. 2): 33-8.
-
(2004)
Semin Liver Dis
, vol.24
, Issue.SUPPL. 2
, pp. 33-38
-
-
Reddy, K.R.1
-
7
-
-
0032547938
-
Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C
-
McHutchison, J.G., Gordon, S.C., Schiff, E.R. et al. Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. N Engl J Med 1998, 339(21): 1485-92.
-
(1998)
N Engl J Med
, vol.339
, Issue.21
, pp. 1485-1492
-
-
McHutchison, J.G.1
Gordon, S.C.2
Schiff, E.R.3
-
8
-
-
0032585237
-
Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus
-
Poynard, T., Marcellin, P., Lee, S.S. et al. Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. Lancet 1998, 352(9138): 1426-32.
-
(1998)
Lancet
, vol.352
, Issue.9138
, pp. 1426-1432
-
-
Poynard, T.1
Marcellin, P.2
Lee, S.S.3
-
9
-
-
0037179698
-
Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
-
Fried, M.W., Shiffman, M.L., Reddy, K.R. et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002, 347(13): 975-82.
-
(2002)
N Engl J Med
, vol.347
, Issue.13
, pp. 975-982
-
-
Fried, M.W.1
Shiffman, M.L.2
Reddy, K.R.3
-
10
-
-
0035934568
-
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomized trial
-
Manns, M.P., McHutchison, J.G., Gordon, S.C. et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomized trial. Lancet 2001, 358(9286): 958-65.
-
(2001)
Lancet
, vol.358
, Issue.9286
, pp. 958-965
-
-
Manns, M.P.1
McHutchison, J.G.2
Gordon, S.C.3
-
11
-
-
0036788338
-
Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C
-
McHutchison, J.G., Manns, M., Patel, K. et al. Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C. Gastroenterology 2002, 123: 1061-9.
-
(2002)
Gastroenterology
, vol.123
, pp. 1061-1069
-
-
McHutchison, J.G.1
Manns, M.2
Patel, K.3
-
12
-
-
0036827834
-
Pharmacokinetic and pharmacodynamic studies of a human serum albumin-interferon-α fusion protein in cynomolgus monkeys
-
Osborn, B.L., Olsen, H.S., Nardelli, B. et al. Pharmacokinetic and pharmacodynamic studies of a human serum albumin-interferon-α fusion protein in cynomolgus monkeys. J Pharmacol Exp Ther 2002, 303(2): 540-8.
-
(2002)
J Pharmacol Exp Ther
, vol.303
, Issue.2
, pp. 540-548
-
-
Osborn, B.L.1
Olsen, H.S.2
Nardelli, B.3
-
13
-
-
0037225719
-
An IFN-β-albumin fusion protein that displays improved pharmacokinetic and pharmacodynamic properties in nonhuman primates
-
Sung, C., Nardelli, B., Lafleur, D.W. et al. An IFN-β-albumin fusion protein that displays improved pharmacokinetic and pharmacodynamic properties in nonhuman primates. J Interferon Cytokine Res 2003, 23(1): 25-36.
-
(2003)
J Interferon Cytokine Res
, vol.23
, Issue.1
, pp. 25-36
-
-
Sung, C.1
Nardelli, B.2
Lafleur, D.W.3
-
14
-
-
33747742768
-
Albuferon exhibits efficient anti-HCV activity in cell culture
-
May 14-19, Chicago, Abst S920
-
Liu, C., Zhu, H., Eylar, J. et al. Albuferon exhibits efficient anti-HCV activity in cell culture. Dig Dis Week (May 14-19, Chicago) 2005, Abst S920.
-
(2005)
Dig Dis Week
-
-
Liu, C.1
Zhu, H.2
Eylar, J.3
-
15
-
-
38649142657
-
-
Moore, P., Sidwell, R., Paragas, J., Osborn, B., Nardelli, B., Freimuth, W., Subramanian, M. Albuferon - A novel therapeutic agent with potent in vitro activity against RNA viral agents of bioterrorism. 2nd Annu ASM Biodefense Emerging Dis Res Meet (March 7-10, Baltimore) 2004, Abst 171(G).
-
Moore, P., Sidwell, R., Paragas, J., Osborn, B., Nardelli, B., Freimuth, W., Subramanian, M. Albuferon - A novel therapeutic agent with potent in vitro activity against RNA viral agents of bioterrorism. 2nd Annu ASM Biodefense Emerging Dis Res Meet (March 7-10, Baltimore) 2004, Abst 171(G).
-
-
-
-
16
-
-
38649119017
-
-
Moore, P., Paragas, J., Hogan, R. et al. Albuferon beta shows potent in vitro activity against Ebola and the SARS virus. 2nd Annu ASM Biodefense Emerging Dis Res Meet (March 7-10, Baltimore) 2004, Abst 172(G).
-
Moore, P., Paragas, J., Hogan, R. et al. Albuferon beta shows potent in vitro activity against Ebola and the SARS virus. 2nd Annu ASM Biodefense Emerging Dis Res Meet (March 7-10, Baltimore) 2004, Abst 172(G).
-
-
-
-
18
-
-
33644551889
-
A phase I/II study evaluating escalating doses of recombinant human albumin-interferon-α fusion protein in chronic hepatitis C patients who have failed previous interferon-α-based therapy
-
Balan, V., Nelson, D.R., Sulkowski, M.S. et al. A phase I/II study evaluating escalating doses of recombinant human albumin-interferon-α fusion protein in chronic hepatitis C patients who have failed previous interferon-α-based therapy. Antiviral Ther 2006, 11(1): 35-45.
-
(2006)
Antiviral Ther
, vol.11
, Issue.1
, pp. 35-45
-
-
Balan, V.1
Nelson, D.R.2
Sulkowski, M.S.3
-
19
-
-
33644918919
-
A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients
-
Bain, V.G., Kaita, K.D., Yoshida, E.M. et al. A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients. J Hepatology 2006, 44(4): 671-8.
-
(2006)
J Hepatology
, vol.44
, Issue.4
, pp. 671-678
-
-
Bain, V.G.1
Kaita, K.D.2
Yoshida, E.M.3
-
20
-
-
38649133059
-
Favorable pharmacokinetics of albumin interferon alfa-2b in subjects with chronic hepatitis C
-
AASLD, Oct 27-31, Boston, Abst 1140
-
Fiscella, M., Balan, V., Nelson, D. et al. Favorable pharmacokinetics of albumin interferon alfa-2b in subjects with chronic hepatitis C. 57th Annu Meet Am Assoc Study Liver Dis (AASLD) (Oct 27-31, Boston) 2006, Abst 1140.
-
(2006)
57th Annu Meet Am Assoc Study Liver Dis
-
-
Fiscella, M.1
Balan, V.2
Nelson, D.3
-
21
-
-
38649105032
-
Modulation of interferon specific gene expression by Albuferon(TM) in subjects with chronic hepatitis C and correlation with anti-viral response
-
April 13-17, Paris, Abst 447
-
Moore, P., Balan, V., Nelson, D. et al. Modulation of interferon specific gene expression by Albuferon(TM) in subjects with chronic hepatitis C and correlation with anti-viral response. 40th Annu Meet Eur Assoc Study Liver (EASL) (April 13-17, Paris) 2005, Abst 447.
-
(2005)
40th Annu Meet Eur Assoc Study Liver (EASL)
-
-
Moore, P.1
Balan, V.2
Nelson, D.3
-
22
-
-
35748955193
-
Comparable antiviral response rates with albumin interferon alfa-2b doses at q2w or q4w intervals in naive subjects with genotype 2 or 3 chronic hepatitis C
-
April 11-15, Barcelona, Abst 9
-
Bain, V.G., Marotta, P., Kaita, K. et al. Comparable antiviral response rates with albumin interferon alfa-2b doses at q2w or q4w intervals in naive subjects with genotype 2 or 3 chronic hepatitis C. J Heptol [42nd Annu Meet Eur Assoc Study Liver (EASL) (April 11-15, Barcelona) 2007] 2007, 46(Suppl. 1): Abst 9.
-
(2007)
J Heptol [42nd Annu Meet Eur Assoc Study Liver (EASL)
, vol.46
, Issue.SUPPL. 1
-
-
Bain, V.G.1
Marotta, P.2
Kaita, K.3
-
23
-
-
38649125763
-
A phase 2 dose-escalation study of albuferon combined with ribavirin in nonresponders to prior interferon based therapy for chronic hepatitis C infection
-
April 26-30, Vienna, Abst 113
-
Rustgi, V., Nelson, D., Balan, V. et al. A phase 2 dose-escalation study of albuferon combined with ribavirin in nonresponders to prior interferon based therapy for chronic hepatitis C infection. 41st Annu Meet Eur Assoc Study Liver (EASL) (April 26-30, Vienna) 2006, Abst 113.
-
(2006)
41st Annu Meet Eur Assoc Study Liver (EASL)
-
-
Rustgi, V.1
Nelson, D.2
Balan, V.3
-
24
-
-
38649114548
-
Albumin interferon alfa-2b dosed at q2w or q4w interval demonstrates comparable week 12 efficacy response in IFN naive, genotype-1 rapid viral responders
-
April 11-15, Barcelona, Abst 624
-
Neumann, A.U., Rozenberg, L., Zeuzem, S. et al. Albumin interferon alfa-2b dosed at q2w or q4w interval demonstrates comparable week 12 efficacy response in IFN naive, genotype-1 rapid viral responders. J Hepatol [42nd Annu Meet Eur Assoc Study Liver (EASL) (April 11-15, Barcelona) 2007] 2007, 46(Suppl. 1): Abst 624.
-
(2007)
J Hepatol [42nd Annu Meet Eur Assoc Study Liver (EASL)
, vol.46
, Issue.SUPPL. 1
-
-
Neumann, A.U.1
Rozenberg, L.2
Zeuzem, S.3
-
25
-
-
35748968163
-
Antiviral response at week 12 following completion of treatment with albinterferon alpha-2b plus ribavirin in genotype 1, IFN-naive, chronic hepatitis C patients
-
April 11-15, Barcelona, Abst 779
-
Zeuzem, S., Benhamou, Y., Bain, V. et al. Antiviral response at week 12 following completion of treatment with albinterferon alpha-2b plus ribavirin in genotype 1, IFN-naive, chronic hepatitis C patients. J Hepatol [42nd Annu Meet Eur Assoc Study Liver (EASL) (April 11-15, Barcelona) 2007], 2007, Abst 779.
-
(2007)
J Hepatol [42nd Annu Meet Eur Assoc Study Liver (EASL)
-
-
Zeuzem, S.1
Benhamou, Y.2
Bain, V.3
-
26
-
-
38649110015
-
Interim (week 12) phase 2B virological efficacy and safety results of albumin interferon alfa-2b combined with ribavirin in genotype 1 chronic hepatitis C infection
-
April 26-30, Vienna, Abst 733
-
Zeuzem, S., Benhamou, Y., Shouval, D. et al. Interim (week 12) phase 2B virological efficacy and safety results of albumin interferon alfa-2b combined with ribavirin in genotype 1 chronic hepatitis C infection. 41st Annu Meet Eur Assoc Study Liver (EASL) (April 26-30, Vienna) 2006, Abst 733.
-
(2006)
41st Annu Meet Eur Assoc Study Liver (EASL)
-
-
Zeuzem, S.1
Benhamou, Y.2
Shouval, D.3
-
27
-
-
38649111842
-
Interim antiviral and safety data with albumin interferon alfa-2b combined with ribavirin in a phase 2b study conducted in a genotype 1, IFN-naive, chronic hepatitis C population
-
Oct 27-31, Boston, Abst 1141
-
McHutchison, J., Zeuzem, S., Benhamou, Y. et al. Interim antiviral and safety data with albumin interferon alfa-2b combined with ribavirin in a phase 2b study conducted in a genotype 1, IFN-naive, chronic hepatitis C population. 57th Annu Meet Am Assoc Study Liver Dis (Oct 27-31, Boston) 2006, Abst 1141.
-
(2006)
57th Annu Meet Am Assoc Study Liver Dis
-
-
McHutchison, J.1
Zeuzem, S.2
Benhamou, Y.3
|