UDP-glucuronosyltransferase UGT1A7 genetic polymorphisms in hepatocellular carcinoma: A differential impact according to seropositivity of HBV or HCV markers?

BMC Cancer

Volumn 7, Issue , 2007, Pages

  Stucker I ^a,b   Loriot, Marie Anne ^a,c   N'Koutchou, Giselle ^d   Cenee S ^a,b   Bodin, Laurent ^a,c   Mulot, Claire ^a,b,c   Gelu Simeon, M ^e   Pelletier, L ^a,c   Bronowicki, J P ^f   Degos, Francoise ^g   Beaune, Philippe ^a,c   Laurent Puig, Pierre ^a,c   Hemon D ^a,b   Trinchet, Jean Claude ^d   Pelletier, Gilles ^e  

^a INSERM   (France)

^b IFR69   (France)

^c UMR S775   (France)

^d HÔPITAL JEAN VERDIER   (France)

^e BICÊTRE HOSPITAL   (France)

^f UNIVERSITY HOSPITAL OF NANCY   (France)

^g BEAUJON HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; GLUCURONOSYLTRANSFERASE 1A7; HEPATITIS B SURFACE ANTIGEN; HEPATITIS C ANTIBODY; BIOLOGICAL MARKER; GLUCURONOSYLTRANSFERASE;

ADULT; AGED; ALCOHOL LIVER DISEASE; ARTICLE; CONTROLLED STUDY; DNA EXTRACTION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HOSPITAL BASED CASE CONTROL STUDY; HUMAN; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; RISK FACTOR; ALLELE; BLOOD; CASE CONTROL STUDY; DRINKING BEHAVIOR; ENZYMOLOGY; GENETICS; HEPATITIS B; HEPATITIS C; LIVER TUMOR; METHODOLOGY; MIDDLE AGED; MOLECULAR GENETICS; POLYMERASE CHAIN REACTION; SEROLOGY;

ADULT; AGED; ALCOHOL DRINKING; ALLELES; BIOLOGICAL MARKERS; CARCINOMA, HEPATOCELLULAR; CASE-CONTROL STUDIES; GLUCURONOSYLTRANSFERASE; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS C; HEPATITIS C ANTIBODIES; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RISK FACTORS; SEROLOGIC TESTS;

EID: 38649136574     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-7-214     Document Type: Article

References (17)

1. Farazi PA DePinho RA Hepatocellular carcinoma pathogenesis: From genes to environment Nat Rev Cancer 2006, 6:674-687 10.1038/nrc1934 16929323
2. Tobaco smoke and involuntary smoking IARC monographs on the evaluation of carcinogenic risks to humans WHO, Lyon 2004 83 15285078
3. Munaka M Kohshi K Kawamoto T Takasawa S Nagata N Itoh H Oda S Katoh T Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and the risk of hepatocellular carcinoma J Cancer Res Clin Oncol 2003, 129(6):355-60 10.1007/s00432-003-0439-5 12759747
4. Vogel A Kneip S Barut A Ehmer U Tukey RH Manns MP Strassburg CP Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene Gastroenterology 2001, 121:1136-1144 10.1053/gast.2001.28655 11677206
5. Wang Y Kato N Hoshida Y Otsuka M Taniguchi H Moriyama M Shiina S Kawabe T Ito YM Omata M UDP-glucuronosyltransferase 1A7 genetic polymorphisms are associated with hepatocellular carcinoma in japanese patients with hepatitis C virus infection Clin Cancer Res 2004, 10:2441-2446 10.1158/ 1078-0432.CCR-1187-3 15073122
6. Tseng CS Tang KS Lo HW Ker CG Teng HC Huang CS UDP-glucuronosyltransferase 1A7 genetic polymorphisms are associated with hepatocellular carcinoma risk and onset age Am J Gastroenterol 2005, 100:1758-1763 10.1111/j.1572-0241.2005.41857.x 16086712
7. Guillemette C Pharmacogenomics of human UDP-glucuronosyltransferase enzymes Pharmacogenomics J 2003, 3:136-158 10.1038/sj.tpj.6500171 12815363
8. Zheng Z Park JY Guillemette C Schantz SP Lazarus P Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk J Natl Cancer Inst 2001, 93:1411-1418 10.1093/ jnci/93.18.1411 11562393
9. Strassburg CP Vogel A Kneip S Tukey RH Manns MP Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 gene in colorectal cancer Gut 2002, 50:851-856 1773251 12010889 10.1136/gut.50.6.851
10. Ockenga J Vogel A Teich N Keim V Manns MP Strassburg CP UDP glucuronosyltransferase (UGT1A7) gene polymorphisms increase the risk of chronic pancreatitis and pancreatic cancer Gastroenterology 2003, 124:1802-1808 10.1016/S0016-5085(03)00294-4 12806614
11. Logt VD M E Bergevoet SM Roelofs HM van Hooijdonk Z Morsche T H R Wobbes T Kok D B J Nagengast FM Peters WH Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk Carcinogenesis 2004, 25:2407-2415 10.1093/carcin/ bgh251 15319294
12. Tang KS Chiu HF Chen HH Eng HL Tsai CJ Teng HC Huang CS Link between colorectal cancer and polymorphisms in the uridine-diphosphoglucuronosyltransferase 1A7 and 1A1 genes World J Gastroenterol 2005, 11:3250-3254 15929176
13. Verlaan M Drenth JP Truninger K Koudova M Schulz HU Bargetzi M Kunzli B Friess H Cerny M Kage A Landt O Morsche T H R Rosendahl J Luck W Nickel R Halangk J Becker M Macek M Jr Jansen JB Witt H Polymorphisms of UDP-glucuronosyltransferase 1A7 are not involved in pancreatic diseases J Med Genet 2005, 42:e62 10.1136/jmg.2005.032599 16199544
14. Guillemette C Ritter JK Auyeung DJ Kessler FK Housman DE Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: Functional consequences of three novel missense mutations in the human UGT1A7 gene Pharmacogenetics 2000, 10:629-644 10.1097/00008571-200010000-00006 11037804
15. Clayton D McKeigue PM Epidemiological methods for studying genes and environmental factors in complex diseases Lancet 358:1358-60
16. Begg CB Zhang ZF Statistical analysis of molecular epidemiology studies employing case-series Cancer Epidemiol Biomarkers Prev 1994, 3(2):173-5 8049640
17. Little R Rubin D Statistical analysis with missing data Wiley, New-York 1987