Designer drug 2,5-dimethoxy-4-methyl-amphetamine (DOM, STP): Involvement of the cytochrome P450 isoenzymes in formation of its main metabolite and detection of the latter in rat urine as proof of a drug intake using gas chromatography-mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 862, Issue 1-2, 2008, Pages 252-256

  Ewald, Andreas H ^a   Puetz, Michael ^b   Maurer, Hans H ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b Bundeskriminalamt   (Germany)

Author keywords

2,5 Dimethoxy 4 methyl amphetamine; CYP2D6; Designer drug; DOM; GC MS; STP

Indexed keywords

ENZYMES; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METABOLITES;

DESIGNER DRUGS; DRUG INTAKE; ISOENZYMES; SYSTEMATIC TOXICOLOGICAL ANALYSIS (STA);

DRUG PRODUCTS;

2,5 DIMETHOXY 4 METHYLAMPHETAMINE; CYTOCHROME P450 2D6; DRUG METABOLITE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG MEGADOSE; DRUG METABOLISM; DRUG SCREENING; DRUG STRUCTURE; DRUG URINE LEVEL; LOW DRUG DOSE; MALE; MASS FRAGMENTOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT; TOXICOLOGY;

2,5-DIMETHOXY-4-METHYLAMPHETAMINE; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; ISOENZYMES; RATS; SUBSTANCE ABUSE DETECTION;

RATTUS;

EID: 38649136220     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.11.042     Document Type: Article

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