Paediatric age-dependent serum transferrin isoform distribution studied by HPLC

Clinical Laboratory

Volumn 53, Issue 11-12, 2007, Pages 575-582

  Arndt, Torsten ^a   Stanzel, Sven ^b   Sewell, Adrian C ^c  

^a Bioscientia Center for Human Genetics   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Alcohol; Carbohydrate deficient transferrin; CDT; HPLC; Paediatrics; Transferrin isoforms

Indexed keywords

ASIALOTRANSFERRIN; CARBOHYDRATE DEFICIENT TRANSFERRIN; DISIALOTRANSFERRIN; METALLOPROTEIN; MONOSIALOTRANSFERRIN; OCTASIALOTRANSFERRIN; PENTASIALOTRANSFERRIN; TETRASIALOTRANSFERRIN; TRANSFERRIN; TRISIALOTRANSFERRIN; UNCLASSIFIED DRUG;

ADOLESCENT; AGE DISTRIBUTION; ARTICLE; CHILD; CORRELATION ANALYSIS; ELECTIVE SURGERY; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INFANT; LABORATORY DIAGNOSIS; MAJOR CLINICAL STUDY; NORMAL VALUE; PHENYLKETONURIA; PREDICTION; PROTEIN LOCALIZATION; REFERENCE VALUE; STATISTICAL SIGNIFICANCE; TRANSFERRIN BLOOD LEVEL;

ADOLESCENT; AGE FACTORS; AGING; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COHORT STUDIES; HUMANS; INFANT; PROTEIN ISOFORMS; TRANSFERRIN;

EID: 38649129949     PISSN: 14336510     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Stibler H. Carbohydrate-deficient transferrin in serum: A new marker of potentially harmful alcohol consumption reviewed. Clin Chem 1991; 37: 2029-2037.
2. Arndt T. Carbohydrate-deficient transferrin as a marker of chronic alcohol abuse: A critical review of pre-analysis, analysis, and interpretation. Clin Chem 200 1; 47: 13-27.
3. Bortolotti F, de Paoli G, Tagliaro F. Carbohydrate-deficient transferrin (CDT) as a marker of alcohol abuse: A critical review of the literature 2001-2005. J Chromatogr B 2006; 841: 96-109.
4. Marquardt T, Denecke J. Congenital disorders of glycosylation: Review of their molecular bases, clinical presentations and specific therapies. Eur J Pediatr 2003; 162: 359-79.
5. Editorial. Pediatric reference intervals-critical gap analysis and establishment of a rational initiative [Editorial]. Clin Biochem 2006; 39: 559-560.
6. Arndt T, Meier U, Nauck M, Gressner AM. Primary biliary cirrhosis is not a clinical condition for increased carbohydrate-deficient transferrin: Experience with 4 independent CDT analysis methods. Clin Chim Acta 2006; 372: 184-187.
7. Arndt T, Gressner A, Herwig J, Meier U, Sewell AC. Argininosuccinate lyase deficiency (ASL) and carbohydrate-deficient transferrin (CDT): Experience with four independent CDT analysis methods - misleading results given by the %CDT TIA assay. Clin Chim Acta 2006; 373: 117-120.
8. Arndt T, Erkens M, Holtkamp K, Keller T, Gressner AM. High prevalence of increased trisialotransferrin concentrations in patients with anorexia nervosa: Implications for determination of carbohydrate-deficient transferrin. Clin Chim Acta 2007; 379: 150-153.
9. International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Working Group on Standardization of Carbohydrate-deficient Transferrin: Jeppsson J-O, Arndt T, Schellenberg F, Wielders JPM, Anton RF, Whitfield JB, Helander A.. Toward standardization of carbohydrate-deficient transferrin (CDT) measurements: I. Analyte definition and proposal of a candidate reference method. Clin Chem Lab Med 2007; 45: 558-562.
10. Helander A, Husa A, Jeppsson J-O. Improved HPLC method for carbohydrate-defieient transferrin in serum. Clin Chem 2003; 49: 1881-1890.
11. Bonferroni, C E. Teoria statistica delle classi e calcolo delle probabilita. Pubblicazioni del Istituto Superiore di Scienze Economiche e Commerciali di Firenze 1936; 8: 3-62.
12. Grandjean F, Schatt P, Cirriez J-M, Robert F, de l'Escaille F, Nuyens V, Legros F, Vankerkhoven P. Détermination des valeurs de la transferrine carboxydéficiente par électrophorèse capillaire sur une population d' enfants âgés de 0 à 20 ans. Immuno-analyse et biologie spécialisée 2006; 21:252-54.