Effect of a fermented milk combining Lactobacillus acidophilus CL1285 and Lactobacillus casei in the prevention of antibiotic-associated diarrhea: A randomized, double-blind, placebo-controlled trial

Canadian Journal of Gastroenterology

Volumn 21, Issue 11, 2007, Pages 732-736

  Beausoleil, Mélanie ^a,c   Fortier, Nadia ^a   Guénette, Stéphanie ^a   L'Ecuyer, Amélie ^a   Savoie, Michel ^a   Franco, Martin ^a   Lachaîne, Jean ^b   Weiss, Karl ^a  

^a MAISONNEUVE ROSEMONT HOSPITAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c NONE   (Canada)

Author keywords

Antibiotic associated diarrhea; C difficile; Lactobacillus; Probiotic

Indexed keywords

ANTIBIOTIC AGENT; PLACEBO; PROBIOTIC AGENT;

ARTICLE; CANADA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DIET THERAPY; DIETARY INTAKE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FERMENTED PRODUCT; HOSPITALIZATION; HUMAN; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS CASEI; MAJOR CLINICAL STUDY; MILK; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 38649108836     PISSN: 08357900     EISSN: None     Source Type: Journal    
DOI: 10.1155/2007/720205     Document Type: Article

References (27)

1. Högenauer C, Hammer HF, Krejs GJ, Reisinger EC. Mechanisms and management of antibiotic-associated diarrhea. Clin Infect Dis 1998;27:702-10.
2. Miller MA, Hyland M, Ofner-Agostini M, Gourdeau M, Ishak M, for the Canadian Hospital Epidemiology Committee. Morbidity, mortality, and healthcare burden of nosocomial Clostridium difficile-associated diarrhea in Canadian hospitals. Infect Control Hosp Epidemiol 2002;23:137-40.
3. Bartlett JG. Clinical Practice. Antibiotic-associated diarrhea. N Engl J Med 2002;346:334-9.
4. Poutanen SM, Simor AE. Clostridium difficile-associated diarrhea in adults. CMAJ 2004;171:51-8.
5. Siitonen S, Vapaatalo, H, Salminen S, et al. Effect of Lactobacillus GG yoghurt in the prevention of antibiotic associated diarrhoea. Ann Med 1990;22:57-9.
6. Cremonini F. Di Caro S, Nista EC, et al. Meta-analysis: The effect of probiotic administration on antibiotic-associated diarrhea. Aliment Pharmacol Ther 2002;16:1461-7.
7. Mercenier A, Pavan S, Pot B. Probiotics as biotherapeutic agents: Present knowledge and future prospects. Curr Pharm Des 2003;9:175-91.
8. Health Canada. Overview of the natural health products regulations guidance document. . (Version current at October 11, 2007).
9. Thomas MR, Litin SC, Osmon DR, Corr AP, Weaver AL, Lolise CM. Lack of effect of Lactobacillus GG on antibiotic-associated diarrhea: A randomized, placebo-controlled trial. Mayo Clin Proc 2001;76:883-9.
10. Tankanow RM, Ross MB, Ertel IJ, Dickinson DG, McCormick LS, Garfinkel JF. Double-blind, placebo-controlled study of the efficacy of Lactinex in the prophylaxis of amoxicillin-induced diarrhoea. DICP 1990;24:382-4.
11. Armuzzi A, Cremonini F, Bartolozzi F, et al. The effect of oral administration of Lactobacillus GG on antibiotic-associated gastrointestinal side-effects during Helicobacter pylori eradication therapy. Aliment Pharmacol Ther 2001;15:163-9.
12. McFarland LV, Surawicz CM, Greenberg RN, et al. Prevention of beta-lactam-associated diarrhea by Saccharomyces boulardii compared with placebo. Am J Gastroenterol 1995;90:439-48.
13. Isolauri E, Sütas Y, Kankaanpaa P, Arvilommi H, Salminen S. Probiotics: Effects on immunity. Am J Clin Nutr 2001;73(2 Suppl):444S-50S.
14. Alvarez-Olmos MI, Oberhelman RA, Probiotic agents and infectious diseases: A modern perspective on a traditional therapy. Clin Infect Dis 2001;32:1567-76.
15. Surawicz CM, Elmer GW, Speelman P, McFarland LV, Chinn J, van Belle G. Prevention of antibiotic-associated diarrhea by Saccharomyces boulardii. Gastroenterology 1989;96:981-8.
16. Arvola T, Laiho K, Torkkeli S, et al. Prophylactic Lactobacillus GG reduces antibiotic-associated diarrhea in children with respiratory infections: A randomized study. Pediatrics 1999;104:e64. (Abst).
17. Lewis SJ, Potts LF, Barry RE. The lack of therapeutic effect of Saccharomyces boulardii in the prevention of antibiotic-related diarrhoea in elderly patients. J Infect 1998;36:171-4.
18. Gotz V, Romankiewicz JA, Moss J, Murray HW Prophylaxis against ampicillin-associated diarrhea with a lactobacillus preparation. Am J Hosp Pharm 1979;36:754-7.
19. Adam J, Barret A, Barret-Bellet C. Essais cliniques contrôlés en double insu de l'Ultra-levure lyophilisée: érude multicentrique par 25 médecins de 388 cas. Gaz Med Fr 1977;84:2072-8.
20. D'Souza AL, Rajkumar C, Cooke J, Bulpitt CJ. Probiotics in prevention of antibiotic associated diarrhoea: Meta-analysis. BMJ 2002;324:1361.
21. Vanderhoof JA, Young RJ. Use of probiotics in childhood gastrointestinal disorders. J Pediatr Gastroenterol Nutr 1998;27:323-32.
22. Borriello SP, Hammes P, Holzapfel W, et al. Safety of probiotics that contain lactobacilli or bifidobacteria. Clin Infect Dis 2003;36:775-80.
23. Stoddart B, Wilcox MH. Clostridium difficile. Curr Opin Infect Dis 2002;15:513-8.
24. McFarland LV. Epidemiology, risk factors and treatments for antibiotic-associated diarrhea. Dig Dis 1998;16(5):292-307.
25. Lewis SJ, Freedman AR. Review article: The use of biotherapeutic agents in the prevention and treatment of gastrointestinal disease. Aliment Pharmacol Ther 1998;12:807-22.
26. Valiquette L, Low DE, Pepin J, McGeer A. Clostridium difficile infection in hospitals: A brewing storm. CMAJ 2004;171:27-9.
27. Eggertson L, Sibbald B. Hospitals battling outbreaks of C. difficile. CMAJ 2004;171(1):19-21.