Synthesis of (1-(aminomethyl)-2,3-dihydro-1H-inden-3-yl)methanol: Structural confirmation of the main band impurity found in Varenicline® starting material

Synthetic Communications

Volumn 38, Issue 3, 2008, Pages 441-447

  Busch, Frank R ^a   Concannon, Paul E ^a   Handfield, Robert E ^a   McKinley, Jason D ^a   McMahon, Megan E ^a   Singer, Robert A ^a   Watson, Timothy J ^a   Withbroe, Gregory J ^a   Stivanello, Mariano ^b   Leoni, Lucia ^b   Bezze, Chiara ^b  

^a PFIZER INC   (United States)

^b Fabbrica Italiano Sintetici SpA   (Italy)

Author keywords

Amino alcohol; Reduction; Varenicline

Indexed keywords

(1 (AMINOMETHYL) 2,3 DIHYDRO 1H INDEN 3 YL)METHANOL; ALUMINUM; AMINOALCOHOL; LITHIUM; METHANOL; UNCLASSIFIED DRUG; VARENICLINE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CYCLIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMER; SYNTHESIS; THIN LAYER CHROMATOGRAPHY;

EID: 38649095247     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397910701771231     Document Type: Article

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