Abnormal in vitro CXCR2 modulation and defective cationic ion transporter expression on polymorphonuclear neutrophils responsible for hyporesponsiveness to IL-8 stimulation in patients with active systemic lupus erythematosus

Rheumatology

Volumn 47, Issue 2, 2008, Pages 150-157

  Hsieh, S C ^a   Wu, T H ^b   Tsai, C Y ^c   Li, K J ^d   Lu, M C ^d   Wu, C H ^a   Yu, Chia Li ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^d BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

Author keywords

Cationic ion transporters; CXCR2 modulation; Hyporesponsiveness; Membrane potential; Polymorphonuclear neutrophil; Systemic lupus erythematosus

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CHEMOKINE RECEPTOR CXCR2; INTERLEUKIN 8; POTASSIUM CHANNEL; RENAL EPITHELIAL SODIUM CHANNEL; RENAL OUTER MEDULLARY EPITHELIAL POTASSIUM CHANNEL 1; SODIUM CHANNEL; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CATION TRANSPORT; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VITRO STUDY; ION TRANSPORT; MEMBRANE POTENTIAL; NERVE CELL; NEUTROPHIL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCATCHARD PLOT; SYSTEMIC LUPUS ERYTHEMATOSUS;

FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; NEUTROPHILS; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; REFERENCE VALUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 38649084438     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/kem320     Document Type: Article

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