Clinical and laboratory predictors of esophageal varices in children and adolescents with portal hypertension syndrome

Journal of Pediatric Gastroenterology and Nutrition

Volumn 46, Issue 2, 2008, Pages 178-183

  Fagundes, Eleonora Druve Tavares ^a   Ferreira, Alexandre Rodrigues ^a   Roquete, Mariza Leitão Valadares ^a   Penna, Francisco José ^a   Goulart, Eugênio Marcos Andrade ^a   Filho, Paulo Pimenta Figueiredo ^a   Bittencourt, Paulo Fernando Souto ^a   Carvalho, Simone Diniz ^a   Albuquerque, Walton ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Children; Esophageal varices; Gastrointestinal endoscopy; Portal hypertension; Risk factors

Indexed keywords

ANAMNESIS; ARTICLE; ENDOSCOPY; ESOPHAGOGASTRODUODENOSCOPY; ESOPHAGUS VARICES; HUMAN; HYPOALBUMINEMIA; LIVER CIRRHOSIS; LIVER FIBROSIS; MAJOR CLINICAL STUDY; PORTAL HYPERTENSION; PRIORITY JOURNAL; SPLENOMEGALY;

ADOLESCENT; ANALYSIS OF VARIANCE; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; ENDOSCOPY, GASTROINTESTINAL; ESOPHAGEAL AND GASTRIC VARICES; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMANS; HYPERTENSION, PORTAL; INFANT; LIVER CIRRHOSIS; LOGISTIC MODELS; MALE; PORTAL VEIN; PREDICTIVE VALUE OF TESTS; RISK FACTORS; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; SPLENOMEGALY; THROMBOCYTOPENIA; THROMBOSIS;

EID: 38549178085     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e318156ff07     Document Type: Article

References (32)

1. D'Amico G, Pagliaro L, Bosh J. The treatment of portal hypertension: a meta-analytic review. Hepatology 1995;22:332-54.
2. Franchis R. Updating consensus in portal hypertension: report of the Baveno III Consensus Workshop on definition, methodology, and therapeutic strategies in portal hypertension. J Hepatol 2000;33:846-52.
3. Jensen DM. Endoscopic screening for varices in cirrhosis: findings, implications, and outcomes. Gastroenterology 2002;122:1620-30.
4. Garcia-Tsao G, Escorsell A, Zakko M, et al. Predicting the presence of significant portal hypertension and esophageal varices in compensated cirrhotic patients. Hepatology 1997;26:360.
5. Schepis F, Cammà C, Niceforo D, et al. Which patients should undergo endoscopic screening for esophageal varices detection? Hepatology 2001;33:333-8.
6. Zaman A, Becker T, Lapidus J, et al. Risk factors for the presence of varices in cirrhotic patients without history of variceal hemorrhage. Arch Int Med 2001;161:2564-70.
7. Madhotra R, Mulkahy HE, Willner I, et al. Prediction of esophageal varices in patients with cirrhosis. J Clin Gastroenterol 2002;34:81-5.
8. Molleston JP. Variceal bleeding in children. J Pediatr Gastroenterol Nutr 2003;37:538-45.
9. Pinto RB, Vieira SMG, Silveira TR. Portal hypertension. In: Ferreira CT, Carvalho E, Silva LR (eds). Gastroenterologia e Hepatologia em Pediatria - Diagnóstico e Tratamento. Rio de Janeiro: Medsi; 2003. pp. 683-707.
10. Japanese Research Society for Portal Hypertension. The general rules for recording endoscopic findings on oesophageal varices. Jpn J Surg 1980; 10: 84-87.
11. Sarin SK, Lahoti D, Saxena SP, et al. Prevalence, classification, and natural history of gastric varices: a long-term follow-up study in 568 portal hypertension patients. Hepatology 1992;102:1343-9.
12. Pugh RN, Murray-Lyon IM, Dawson JL, et al. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 1973;60:646-9.
13. Campos-Filho N, Franco EL. Epidemiologic programs for computers and calculators. A microcomputer program for multiple logistic regression by unconditional and conditional maximum likelihood methods. Am J Epidemiol 1989;129:439-44.
14. Franchis R. Evolving consensus in portal hypertension. Report of the Baveno IV Consensus Workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatol 2005;43:167-76.
15. Ozsoylu S, Koçak N, Yüce A. Propranolol therapy for portal hypertension in children. J Pediatr 1986;106:317-21.
16. Shashidhar H, Langhans N, Grand RJ. Propranolol in prevention of portal hypertensive hemorrhage in children: a pilot study. J Pediatr Gastroenterol Nutr 1999;29:12-7.
17. Maksoud JG, Goncalves MEP, Porta G, et al. The endoscopic and surgical management of portal hypertension in children: analysis of 123 cases. J Pediatr Surg 1991;26:178-81.
18. McKiernan PJ, Beath SV, Davison SM. A prospective study of endoscopic esophageal variceal ligation using a multiband ligator. J Pediatr Gastroenterol Nutr 2002;34:207-11.
19. Celinska-Cedro D, Teisseyre M, Woynarowski M, et al. Endoscopic ligation of esophageal varices for prophylaxis of first bleeding in children and adolescents with portal hypertension: preliminary results of a prospective study. J Pediatr Surg 2003;38:1008-11.
20. Shneider B, Emre S, Groszmann R, et al. Expert pediatric opinion on the report of the Baveno IV Consensus Workshop on methodology of diagnosis and therapy in portal hypertension. Pediatr Transplantation 2006;10:893-907.
21. Sokal EM, Van Hoorebeeck N, Van Obbergh L, et al. Upper gastrointestinal tract bleeding in cirrhotic children candidates for liver transplantation. Eur J Pediatr 1992;151:326-8.
22. Stringer MD, Howard ER, Mowat AP. Endoscopic sclerotherapy in the management of esophageal varices in 61 children with biliary atresia. J Pediatr Surg 1989;24:438-42.
23. Gürakan F, Eren M, Koçak N, et al. Extrahepatic portal vein thrombosis in children: etiology and long-term follow-up. J Clin Gastroenterol 2004;38:368-72.
24. Janssen HLA, Wijnhoud A, Haagsma EB, et al. Extrahepatic portal vein thrombosis: aetiology and determinants of survival. Gut 2001;49:720-4.
25. Bressler B, Pinto R, El-Ashry D, et al. Which patients with primary biliary cirrhosis or primary sclerosing cholangitis should undergo endoscopic screening for oesophageal varices detection? Gut 2005;54:407-10.
26. Goulis J, Chau TN, Jordan S, et al. Thrombopoietin concentrations are low in patients with cirrhosis and thrombocytopenia and are restored after orthotopic liver transplantation. Gut 1999;44:754-8.
27. Dittrich S, Mattos AA, Cheinquer H, et al. Correlação entre a contagem de plaquetas no sangue e o gradientes de pressão venosa hepática em pacientes cirróticos. Arq Gastroenterol 2005;42:35-40.
28. Shneider BL. Portal hypertension. In: Suchy FJ, Sokal RJ, Balistreri WF (eds). Liver Disease in Children. Philadelphia: Lippincott Williams & Wilkins; 2001. pp. 130-51.
29. Chalasani N, Imperiale TF, Ismail A, et al. Predictors of large esophageal varices in patients with cirrhosis. Am J Gastroenterol 1999;94:3285-91.
30. Ng FH, Wong SY, Loo CK, et al. Prediction of oesophagogastric varices in patients with liver cirrhosis. J Gastroenterol Hepatol 1999;14:785-90.
31. Li F-H, Hao J-H, Xia J-G, et al. Hemodynamic analysis of esophageal varices in patients with liver cirrhosis using color Doppler ultrasound. World J Gastroenterol 2005;11:4560-5.
32. Thabut D, Trabut J-B, Massard J, et al. Non-invasive diagnosis of large oesophageal varices with FibroTest in patients with cirrhosis: a preliminary retrospective study. Liver Int 2006;26:271-8.