Mechanistic studies of glass vial breakage for frozen formulations. II. Vial breakage caused by amorphous protein formulations

PDA Journal of Pharmaceutical Science and Technology

Volumn 61, Issue 6, 2007, Pages 452-460

  Jiang, Ge ^a   Akers, Mike ^a   Jain, Manish ^a   Guo, Jeremy ^a   Distler, Adrian ^a   Swift, Rob ^a   Wadhwa, Manpreet Vick S ^a   Jameel, Feroz ^a   Patro, Sugu ^a   Freund, Erwin ^a  

^a AMGEN INC   (United States)

Author keywords

Amorphous; Crystalizable excipient; Freeze thaw; Frozen protein formulation; Glass vial breakage; Mannitol

Indexed keywords

GLASS; PROTEIN;

ARTICLE; CRYSTALLIZATION; ENERGY; FREEZE THAWING; FREEZING; METHODOLOGY; SEPARATION TECHNIQUE; TEMPERATURE DEPENDENCE; THAWING; THERMAL ANALYSIS;

CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DRUG PACKAGING; DRUG STORAGE; EXCIPIENTS; FREEZING; GLASS; PROTEINS; THERMODYNAMICS;

EID: 38549174140     PISSN: 10797440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

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