The prognostic importance of serum IL-1β, IL-6, IL-8 and TNF-α levels compared to trauma scoring systems for early mortality in children with blunt trauma

Pediatric Surgery International

Volumn 24, Issue 2, 2008, Pages 235-239

  Ozturk, Hayrettin ^a,c   Yagmur, Yusuf ^b   Ozturk, Hulya ^a,c  

^a ABANT IZZET BAYSAL UNIVERSITY   (Turkey)

^b DICLE UNIVERSITY   (Turkey)

^c Izzet Baysal Women's and Children's Hospital   (Turkey)

Author keywords

Child; Cytokines; Trauma; Trauma scoring system

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ARTICLE; BLUNT TRAUMA; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DEMOGRAPHY; DISEASE SEVERITY; FEMALE; HUMAN; MALE; MORTALITY; PATIENT CARE; PRIORITY JOURNAL; PROGNOSIS; RISK FACTOR; SCORING SYSTEM;

ANALYSIS OF VARIANCE; CHI-SQUARE DISTRIBUTION; CHILD; FEMALE; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; MALE; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS; STATISTICS, NONPARAMETRIC; TRAUMA SEVERITY INDICES; TUMOR NECROSIS FACTOR-ALPHA; WOUNDS, NONPENETRATING;

EID: 38549165767     PISSN: 01790358     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00383-007-2083-7     Document Type: Article

References (32)

1. Hall JR, Reyes HM, Meller JL, Loeff DS, Dembek R (1996) The outcome for children with blunt trauma is best at a pediatric trauma center. J Pediatr Surg 31:72-76
2. Aslar AK, Kuzu MA, Elhan AH, Tanik A, Hengirmen S (2004) Admission lactate level and the APACHE II score are the most useful predictors of prognosis following torso trauma. Injury 35:746-752
3. Baker SP, O'Neill B, Haddon W, Long WB (1974) The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma 14:187-196
4. Champion HR, Sacco WJ, Carnazzo AJ, Copes W, Fouty WJ (1981) Trauma score. Crit Care Med 9:672-676
5. Champion HR, Sacco WJ, Copes WS, Gann DS, Gennarelli TA, Flanagan ME (1989) A revision of the trauma score. J Trauma 29:623-629
6. Knaus WA, Draper EA, Wagner DP, Zimmerman JE (1985) APACHE II: a severity of disease classification system. Crit Care Med 13:818-829
7. Cerra FB, Negro F, Abrams J (1990) APACHE II score does not predict multiple organ failure or mortality in postoperative surgical patients. Arch Surg 125:519-522
8. Collopy BT, Tulloh BR, Rennie GC, Fink RL, Rush JH, Trinca GW (1992) Correlation between injury severity scores and subjective ratings of injury severity: a basis for trauma audit. Injury 23:489-492
9. Deane SA, Gaudry PL, Roberts RF, Juul O, Little JM (1986) Trauma triage-a comparison of the trauma score and the vital signs score. Aust N Z J Surg 56:191-197
10. Eichelberger MR, Gotschall CS, Sacco WJ, Bowman LM, Mangubat EA, Lowenstein AD (1989) A comparison of the trauma score, the revised trauma score, and the pediatric trauma score. Ann Emerg Med 18:1053-1058
11. Baue AE, Durham R, Faist E (1998) Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): are we winning the battle? Shock 10:79-89
12. Bone RC, Newton Sir I (1996) Sepsis, SIRS, and CARS. Crit Care Med 24:1125-1128
13. Faist E (1996) The mechanisms of host defence dysfunction following shock and trauma. Curr Top Microbiol Immunol 216:259-274
14. Deitch EA (1992) Multiple organ failure: pathophysiology and potential future therapy. Ann Surg 216:117-134
15. Ayala A, Perrin MM, Wang P, Ertel W, Chaudry IH (1991) Hemorrhage induces enhanced Kupffer cell cytotoxicity while decreasing peritoneal or splenic macrophage capacity. Involvement of cell-associated tumor necrosis factor and reactive nitrogen. J Immunol 147:4147-54
16. Napolitano LM, Faist E, Wichmann MW, Coimbra R (1999) Immune dysfunction in trauma. Surg Clin North Am 79:1385-1416
17. Lefering R (2002) Trauma score systems for quality assessment. Eur J Trauma 28:52-63
18. Fani-Salek MH, Totten VY, Terezakis SA (1999) Trauma scoring systems explained. Emerg Med 11:155-166
19. Aharonson-Daniel L, Giveon A, Stein M, Israel Trauma Group (ITG), Peleg K (2006) Different AIS triplets: different mortality predictions in identical ISS and NISS. J Trauma 61:711-717
20. Vles WJ, Steyerberg EW, Meeuwis JD, Leenen LP (2004) Pre-hospital trauma care: a proposal for more efficient evaluation. Injury 35:725-733
21. Brink J A, Allen CF, Goslar PW, Barry MA (2001) Can we improve trauma mortality in a state with a voluntary trauma system. Am J Surg 182:738-742
22. Partrick DA, Moore FA, Moore EE, Barnett CC Jr, Silliman CC (1996) Neutrophil priming and activation in the pathogenesis of postinjury multiple organ failure. New Horiz 4:194-210
23. Biffl WL, Moore EE, Moore FA, Carl VS, Kim FJ, Franciose RJ (1994) Interleukin-6 potentiates neutrophil priming with platelet-activating factor. Arch Surg 129:1131-1136
24. Partrick DA, Moore FA, Moore EE, Biffl WL, Sauaia A, Barnett CC Jr (1996) Jack A Barney Resident Research Award winner. The inflammatory profile of interleukin-6, interleukin-8, and soluble intercellular adhesion molecule-1 in postinjury multiple organ failure Am J Surg 172:425-429 (discussed 429-431)
25. Seekamp A, van Griensven M, Lehmann U, Molituris U, Hildebrandt F, Pohlemann T (2002) Serum IL-6, IL-8 and IL-10 levels in multiple compared to traumatic brain injury and combined trauma. Eur J Trauma 28:183-189
26. Strecker W, Gebhard F, Perl M, Rager J, Buttenschon K, Kinzl L, Beck A (2003) Biochemical characterization of individual injury pattern and injury severity. Injury 34:879-887
27. Elmaraghy AW, Aksenov S, Byrick RJ, Richards RR, Schemitsch EH (1999) Pathophysiological effect of fat embolism in a canine model of pulmonary contusion. J Bone Joint Surg Am 81:1155-1164
28. Goris RJA, te Boekhorst TPA, Nuytink JKS, Gimbrere JSF (1985) Multiple-organ failure. Arch Surg 120:1109-15
29. Aprahamian C, Cattey RP, Walker AP, Gruchow HW, Seabrook G (1990) Pediatric trauma score. Predictor of hospital resource use? Arch Surg 125:1128-1131
30. Tepas JJ, Mollitt DL, Talbert JL, Bryant M (1987) The pediatric trauma score as a predictor of injury severity in the injured child. J Pediatr Surg 22:14-18
31. Ramenofsky ML, Ramenofsky MB, Jurkovich GJ, Threadgill D, Dierking BH, Powell RW (1988) The predictive validity of the pediatric trauma score. J Trauma 28:1038-1042
32. Reynolds EA (1992) Trauma scoring and pediatric patients. J Emerg Nurs 18:205-210