Phosphaturic mesenchymal tumor diagnosed by fine-needle aspiration and core biopsy: A case report and review of literature

Diagnostic Cytopathology

Volumn 36, Issue 2, 2008, Pages 115-119

  Policarpio Nicolas, Maria Luisa ^a   Abbott, Todd E ^a   Dalkin, Alan C ^a   Bennett Wick, Jane ^a   Frierson Jr , Henry F ^a  

^a UNIVERSITY OF VIRGINIA MEDICAL CENTER   (United States)

Author keywords

Core biopsy; Cytology; Fine needle aspiration; Oncogenic osteomalacia; Phosphaturic mesenchymal tumor

Indexed keywords

PHOSPHORUS; VITAMIN D;

ADULT; ARTICLE; ASPIRATION BIOPSY; CASE REPORT; CLINICAL EXAMINATION; COMPUTER ASSISTED TOMOGRAPHY; CYTODIAGNOSIS; DIAGNOSTIC IMAGING; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; FEMALE; FIBROSARCOMA; FRACTURE; HUMAN; HYPOPHOSPHATEMIA; LEIOMYOMA; MELANOMA; MESENCHYMOMA; NERVE SHEATH TUMOR; OSTEOMALACIA; PAPANICOLAOU TEST; PHOSPHATURIC MESENCHYMAL TUMOR; PRIORITY JOURNAL; SECONDARY HYPERPARATHYROIDISM; SPINDLE CELL CARCINOMA; SYNOVIAL SARCOMA; TREATMENT OUTCOME;

BIOPSY, FINE-NEEDLE; BONE NEOPLASMS; FEMALE; HUMANS; ILIUM; MIDDLE AGED; NEOPLASMS, CONNECTIVE AND SOFT TISSUE; OSTEOMALACIA; PHOSPHATES;

EID: 38549156580     PISSN: 87551039     EISSN: 10970339     Source Type: Journal    
DOI: 10.1002/dc.20772     Document Type: Article

References (21)

1. Weidner N, Santa Cruz D. Phosphaturic mesenchymal tumors. A polymorphous group causing osteomalacia or rickets. Cancer 1987;59:1442-1454.
2. Schapira D, Ben Izhak O, Nachtigal A, et al. Tumor-induced osteomalacia. Semin Arthritis Rheum 1995;25:35-46.
3. Olefsky J, Kempson R, Jones H, Reaven G. "Tertiary" hyperparathyroidism and apparent "cure" of vitamin-D-resistant rickets after removal of an ossifying mesenchymal tumor of the pharynx. N Engl J Med 1972;286:740-745.
4. Koriyama N, Nishimoto K, Kodama T, et al. Oncogenic osteomalacia in a case with a maxillary sinus mesenchymal tumor. Am J Med Sci 2006;332:142-147.
5. Gonzalez-Compta X, Manos-Pujol M, Foglia-Fernandez M, et al. Oncogenic osteomalacia: Case report and review of head and neck associated tumours. J Laryngol Otol 1998;112:389-392.
6. Yang IM, Park YK, Hyun YJ, et al. Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the oral cavity: A case report. Korean J Intern Med 1997;12:89-95.
7. Gascon A, Cobeta-Garcia JC, Iglesias E, Lazaro JM, Muniesa JA. Oncogenic osteomalacia in a patient with a fibrocystic nodule of the breast. Nephrol Dial Transplant 1999;14:1561-1563.
8. Evans DJ, Azzopardi JG. Distinctive tumours of bone and soft tissue causing acquired vitamin-D-resistant osteomalacia. Lancet 1972;1:353-354.
9. Salassa RM, Jowsey J, Arnaud CD. Hypophosphatemic osteomalacia associated with "nonendocrine" tumors. N Engl J Med 1970;283:65-70.
10. Gitelis S, Ryan WG, Rosenberg AG, Templeton AC. Adult-onset hypophosphatemic osteomalacia secondary to neoplasm. A case report and review of the pathophysiology. J Bone Joint Surg Am 1986;68:134-138.
11. Shenker Y, Grekin RJ. Oncogenic osteomalacia. Isr J Med Sci 1984;20:739-741.
12. Prowse M, Brooks PM. Oncogenic hypophosphatemic osteomalacia associated with a giant cell tumour of a tendon sheath. Aust N Z J Med 1987;17:330-332.
13. Pollack JA, Schiller AL, Crawford JD. Rickets and myopathy cured by removal of a nonossifying fibroma of bone. Pediatrics 1973;52:364-371.
14. Nuovo MA, Dorfman HD, Sun CC, Chalew SA. Tumor-induced osteomalacia and rickets. Am J Surg Pathol 1989;13:588-599.
15. Folpe AL, Fanburg-Smith JC, Billings SD, et al. Most osteomalacia- associated mesenchymal tumors are a single Histopathologic entity: An analysis of 32 cases and a comprehensive review of the literature. Am J Surg Pathol 2004;28:1-30.
16. Shimada T, Hasegawa H, Yamazaki Y, et al. FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis. J Bone Miner Res 2004;19:429-435.
17. Shimada T, Urakawa I, Yamazaki Y, et al. FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa. Biochem Biophys Res Commun 2004;314:409-414.
18. Shimada T, Muto T, Urakawa I, et al. Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia. N Engl J Med 2003;348:1656-1663.
19. Bowe AE, Finnegan R, Jan de Beur SM, et al. FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate. Biochem Biophys Res Commun 2001;284:977-981.
20. Jonsson KB, Zahradnik R, Larsson T, et al. Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia. N Engl J Med 2003;348:1656-1663.
21. Berndt T, Craig TA, Bowe AE, et al. Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent. J Clin Invest 2003;112:785-794.