A case of Stevens-Johnson syndrome possibly induced by amifostine during radiotherapy

Tumori

Volumn 93, Issue 6, 2007, Pages 634-635

  Zollo, Enrico ^a   Cusano, Francesco ^a   Argenone, Angela ^b   Cusano, Carlo Ivan ^a   Pelosi, Patrizia ^a   Pironti, Teresa ^a   Spacagna, Ettore ^a   Viscusi, Alfonso ^a   Lioce, Marco ^a  

^a G RUMMO HOSPITAL   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Adverse cutaneous effects; Amifostine; Radiotherapy; Stevens Johnson syndrome

Indexed keywords

AMIFOSTINE; DEXAMETHASONE; METHYLPREDNISOLONE; METOCLOPRAMIDE; PREDNISONE; TRANDOLAPRIL;

AGED; ARTICLE; BORDERLINE HYPERTENSION; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER THERAPY; CASE REPORT; DERMATOLOGY; DISEASE COURSE; DRUG DOSE REDUCTION; DRUG WITHDRAWAL; HUMAN; LARYNX CANCER; MALE; PHYSICAL EXAMINATION; PROPHYLAXIS; RADIATION PROTECTION; SQUAMOUS CELL CARCINOMA; STEVENS JOHNSON SYNDROME; TREATMENT DURATION;

EID: 38549145871     PISSN: 03008916     EISSN: None     Source Type: Journal    
DOI: 10.1177/030089160709300623     Document Type: Article

References (9)

1. Culy CR, Spencer CM: Amifostine: an update on its clinical status as a cytoprotectant in patients with cancer receiving chemotherapy or radiotherapy and its potential therapeutic application in myelodysplastic syndrome. Drugs, 61: 641-684, 2001.
2. Rades D, Fehlaurer F, Bajrovic A, Mahlmann B, Richter E, Alberti W: Serious adverse effects of amifostine during radiotherapy in head and neck cancer patients. Radiother Oncol, 70: 261-264, 2004.
3. McCauley DL: Amifostine. A novel cytoprotective agent. Cancer Pract, 5: 189-191, 1997.
4. Dorr RT, Holmes BC: Dosing considerations with amifostine: a review of literature and clinical experience. Semin Oncol, 26 (suppl 7): 108-119, 1999.
5. Lale Atahan I, Ozyar E, Sahin S, Yildiz F, Yalcin B, Karaduman A: Two cases of Stevens-Johnson syndrome: toxic epidermal necrolysis possibly induced by amifostine during radiotherapy. Br J Dermatol, 143: 1072-1073, 2000.
6. Demiral AN, Yerebakan O, Simsir V, Alpsoy E: Amifostine-induced toxic epidermal necrolysis during radiotherapy: a case report. Jpn J Clin Oncol, 32: 477-479, 2002.
7. Boccia R, Anne PR, Bourhis J, Brizel D, Daly C, Holloway N 3rd, Hymes S, Koukourakis M, Kozloff M, Turner M, Wasserman T: Assessment and management of cutaneous reactions with amifostine administration: findings of the ethyol (amifostine) cutaneous treatment advisory panel (ECTAP). Int J Radiat Oncol Biol Phys, 60: 302-309, 2004.
8. Roujeau JC: The spectrum of Stevens-Johnson syndrome and toxic epidermal necrolysis: a clinical classification. J Invest Dermatol, 102: 28-30, 1994.
9. Fleischer AB Jr, Rosenthal DI, Bernard SA, O'Keefe EJ: Skin reactions to radiotherapy - a spectrum resembling erythema multiforme: case report and review of the literature. Cutis, 49: 35-39, 1992.