Comparison of two types of population pharmacokinetic model structures of paclitaxel

European Journal of Pharmaceutical Sciences

Volumn 33, Issue 2, 2008, Pages 128-137

  Fransson, Martin ^a   Gréen, Henrik ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Model structure; NONMEM; Observability; Paclitaxel; Simulation

Indexed keywords

CARBOPLATIN; CREMOPHOR; PACLITAXEL;

ADULT; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER RELAPSE; CLINICAL ARTICLE; CLINICAL STUDY; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG BINDING; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG ELIMINATION; DRUG FORMULATION; DRUG INFUSION; DRUG MECHANISM; DRUG STRUCTURE; DRUG WITHDRAWAL; FEMALE; GYNECOLOGIC CANCER; HUMAN; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MULTIPLE CYCLE TREATMENT; NEUROTOXICITY; NONLINEAR SYSTEM; OVARY CANCER; PERITONEUM CANCER; PHARMACOKINETICS; PRIORITY JOURNAL; PROBABILITY; SENSITIVITY ANALYSIS; SEPTICEMIA; SIMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION; UTERINE CERVIX CARCINOMA; UTERUS CARCINOMA; VALIDATION PROCESS;

ADULT; AGED; ALGORITHMS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; AREA UNDER CURVE; CARBOPLATIN; COMPUTER SIMULATION; FEMALE; GENITAL NEOPLASMS, FEMALE; GLYCEROL; HUMANS; MIDDLE AGED; MODELS, BIOLOGICAL; PACLITAXEL; REPRODUCIBILITY OF RESULTS; VEHICLES;

EID: 38549117845     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2007.10.005     Document Type: Article

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