Assay of the set of all sudan azodye (I, II, III, IV, and para-red) contaminating agents by liquid chromatography-tandem mass spectrometry and isotope dilution methodology

Journal of Agricultural and Food Chemistry

Volumn 56, Issue 1, 2008, Pages 63-67

  Mazzotti, Fabio ^a   Di Donna, Leonardo ^a   Maiuolo, Loredana ^a   Napoli, Anna ^a   Salerno, Raffaele ^a   Sajjad, Ashiff ^a   Sindona, Giovanni ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Isotope dilution; Mass spectrometry; Multiple reaction monitoring (MRM); Sudan azodyes

Indexed keywords

1-PHENYLAZO-2-NAPHTHOL; AZO COMPOUND; COLORING AGENT; NAPHTHOL DERIVATIVE; OIL SCARLET; SCARLET RED; SUDAN I; SUDAN II; UNCLASSIFIED DRUG;

ARTICLE; FOOD CONTAMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; TANDEM MASS SPECTROMETRY;

AZO COMPOUNDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLORING AGENTS; FOOD CONTAMINATION; NAPHTHOLS; TANDEM MASS SPECTROMETRY;

EID: 38549111071     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf072286y     Document Type: Article

References (17)

1. Di Donna, L.; Maiuolo, L.; Mazzotti, F.; De Luca, D.; Sindona, G. Assay of Sudan I contamination of foodstuff by atmospheric pressure chimical ionization tandem mass spectrometry and isotope dilution. Anal. Chem. 2004, 76, 5104-5108.
2. Calbiani, F.; Careri, M.; Elviri, L.; Mangia, A.; Pistarà, L.; Cagnoni, I. Development and in-house validation of a liquid chromatography- electrospray-tandem mass spectrometry method for the simultaneous determination of Sudan I, Sudan II, Sudan III and Sudan IV in hot chilli products. J. Chromatogr., A 2004, 1042, 123-130.
3. Tateo, F.; Bononi, M. Fast determination of Sudan I by HPLC/ APCI-MS in hot chilli, spices, and oven-baked foods. J. Agric. Food Chem. 2004, 52, 655-658.
4. Ma, M.; Luo, X.; Chen, B.; Sub, S.; Yao, S. Simultaneous determination of water-soluble and fat-soluble synthetic colorants in foodstuff by high-performance liquid chromatography-diode array detection-electrospray mass spectrometry. J. Chromatogr., A 2006, 1103, 170-176.
5. Stiborova, M.; Martinek, V.; Rydlova, H.; Koblas, T.; Hodek, P. Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers. Cancer Lett. 2005, 220, 145-154.
6. Cerniglia, C. E.; Freeman, J. P.; Franklin, W.; Pack, L. D. Metabolism of azo dyes derived from benzidine, 3,3′-dimethyl-benzidine and 3,3′-dimethoxybenzidine to potentially carcinogenic aromatic amines by intestinal bacteria. Carcinogenesis 1982, 3, 1255-1260.
7. Platzek, T.; Lang, C.; Grohmann, G.; Gi, U. S.; Baltes, W. Formation of a carcinogenic aromatic amine from an azo dye by human skin bacteria in vitro. Hum. Exp. Toxicol. 1999, 18, 552-559.
8. Lundsgaard, J. Survey 2; Danish Environmental Protection Agency, 2002.
9. (a) Directive 2003/460/EC. Off. J. Eur. Union 2003, L154/114.
10. (b) Directive 2003/460/EC. Off. J. Eur. Union 2004, L27/52.
11. (c) Directive 2003/460/EC. Off. J. Eur. Union 2005, L135/34.
12. Fukniss, B. S.; Hannaford, A. J.; Smith, P. W. G.; Tatchell, A. R. Vogel's Textbook of Practical Organic Chemistry, 5th ed.; Longman Scientific and Technical: New York, 1989; Chapter 6.
13. Vazquez Troche, S.; Garcya Falcon, M. S.; Gonzalez Amigo, S.; Lage Yusty, M. A.; Simal Lozano, J. Enrichment of benzo[a]pyrene in vegetable oils and determination by HPLC-FL. Talanta 2000, 51, 1069-1076.
14. Calbiani, F.; Careri, M.; Elviri, L.; Mangia, A.; Pistarà, L.; Cagnoni, I. Accurate mass measurements for the confirmation of Sudan azo-dyes in hot chilli products by capillary liquid chromatography-electrospray tandem quadrupole orthogonal-acceleration time of flight mass spectrometry. J. Chromatogr., A 2004, 1058, 127-135.
15. Di Donna, L.; De Nino, A.; Maiuolo, L.; Mazzotti, F.; Napoli, A.; Salerno, R.; Sindona, G. High-throughput mass spectrometry: the mechanism of Sudan azo dye fragmentation by ESI tandem mass spectrometry and extensive deuterium labeling experiments. J. Mass Spectrom. 2007, 42, 1057-1061.
16. Barber, M.; Wolstenholme, W. A.; Jennings, K. R. Metastable ions in a duble focusing mass spectrometer. Nature 1967, 214, 664-666.
17. Cooks, R. G. Special feature: historical. Collision-induced dissociation: readings and commentary. J. Mass Spectrom. 1995, 30, 1215-1221.