Expression of corticotropin-releasing hormone receptor type 1 and type 2 in human pregnant myometrium

Reproductive Sciences

Volumn 14, Issue 6, 2007, Pages 568-577

  Jin, Dan ^a   He, Ping ^b   You, Xingji ^b   Zhu, Xiaoyan ^b   Dai, Ling ^a   He, Qian ^a   Liu, Chunmin ^a   Hui, Ning ^a   Sha, Jinyan ^a   Ni, Xin ^b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Corticotropin releasing hormone; Corticotropin releasing hormone receptors; Myometrium; Parturition

Indexed keywords

CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1ALPHA; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1BETA; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1C; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1E; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1F; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2ALPHA; UNCLASSIFIED DRUG; CORTICOTROPIN RELEASING FACTOR RECEPTOR; CRF RECEPTOR TYPE 1; CRF RECEPTOR TYPE 2; ISOPROTEIN; MESSENGER RNA;

ADULT; ARTICLE; CESAREAN SECTION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MYOMETRIUM; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; GENETICS; GESTATIONAL AGE; LABOR; METABOLISM; SMOOTH MUSCLE FIBER;

ADULT; BLOTTING, WESTERN; CESAREAN SECTION; FEMALE; GESTATIONAL AGE; HUMANS; IMMUNOHISTOCHEMISTRY; LABOR, OBSTETRIC; MYOCYTES, SMOOTH MUSCLE; MYOMETRIUM; PREGNANCY; PROTEIN ISOFORMS; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 38449119034     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719107307821     Document Type: Article

References (38)

1. Lenz HJ, Raedler A., Greten H., Brown MR CRF initiates biological action within the brain that are observed in response to stress. Am J Physiol. 1987 ; 21: 34-39.
2. Chrousos G., Gold P. The concepts of stress and stress system disorders. JAMA. 1992 ; 267: 1244-1252.
3. Suda T., Tomori N., Tozawa F., Mouri T., Demura H., Shizume K. Distribution and characterization of immunoreactive corticotropin-releasing factor in human tissue. J Clin Endocrinol Metab. 1984 ; 55: 861-866.
4. Shibasai T., Oagirl Ehizume K, Ling N. Corticotropin-releasing factor-like activity in human extracts. J Clin Endocrinol Metab. 1982 ; 55: 384-386.
5. Usui T., Nakai Y., Tsukada T., et al. Expression of adrenocorticotropin- releasing hormone precursor gene in placenta and other nonhypothalamic tissues in man. Mol Endocrinol. 1988 ; 2: 871-875.
6. De Souza EB Corticotropin-releasing factor receptors: physiology, pharmacology, biochemistry and role in central nervous system and immune disorders. Psychoneuroendocrinology. 1995 ; 20: 789-818.
7. Owens MJ, Nemeroff CB Physiology and pharmacology of corticotropin- releasing factor. Pharmacol Rev. 1991 ; 43: 425-473.
8. McLean M., Bistis A., Davies JJ, Woods R., Lowry PJ, Smith R. A placental clock controlling the length of human pregnancy. Nat Med. 1995 ; 1: 460-463.
9. Chen R., Lewis KA, Perrin MH, Vale WW Expression cloning of a human corticotropin-releasing-factor receptor. Proc Natl Acad Sci U S A. 1993 ; 90: 8967-8971.
10. Liaw CW, Lovenberg TW, Barry G., Oltersdorf T., Grigoriadis DE, De Souza EB. Cloning and characterization of the human corticotropin-releasing factor-2 receptor complementary deoxyribonucleic acid. Endocrinology. 1996 ; 137: 72-77.
11. Pisarchik A., Slominski AT Alternative splicing of CRH-R1 receptors in human and mouse skin: identification of new variants and their differential expression. FASEB J. 2001 ; 15: 2754-2756.
12. Valdenaire O., Giller T., Breu V., Gottowik J., Kilpatrick G. A new functional isoform of the human CRF2 receptor for corticotropin-releasing factor. Biochim Biophys Acta. 1997 ; 1352: 129-132.
13. Kostich WA, Chen A., Sperle K., Largent BL Molecular identification and analysis of a novel human corticotropin-releasing factor (CRF) receptor: the CRF2γ receptor. Mol Endocrinol. 1998 ; 12: 1077-1085.
14. Vaughan J., Donaldson C., Bittencourt J., et al. Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotrophin-releasing factor. Nature. 1996 ; 378: 287-292.
15. Hsu SY, Hsueh AJ Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor. Nat Med. 2001 ; 7: 605-611.
16. Lewis K., Li C., Perrin MH, et al. Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor. Proc Natl Acad Sci U S A. 2001 ; 98: 7570-7575.
17. Dautzenberg FM, Py-Lang G., Higelin J., Fischer C., Wright MB, Huber G. Different binding modes of amphibian and human corticotropin-releasing factor type 1 and type 2 receptors: evidence for evolutionary differences. J Pharmacol Exp Ther. 2001 ; 296: 113-120.
18. Sehringer B., Zahradnik HP, Simon M., Ziegler R., Noethling C., Schaefer WR mRNA expression profiles for corticotrophin-releasing hormone, urocortin, CRH-binding protein and CRH receptors in human term gestational tissues determined by real-time quantitative RT-PCR. J Mol Endocrinol. 2004 ; 32: 339-348.
19. Imperatore A., Florio P., Torres PB, et al. Urocortin 2 and urocortin 3 are expressed by the human placenta, deciduas, and fetal membranes. Am J Obstet Gynecol. 2006 ; 195: 288-295.
20. Karteris E., Hillhous EW, Grammatopoulos DK Urocortin II is expressed in human pregnant myometrial cells and regulates myosin light chain phosphorylation: potential role of the type-2 conticotropin-releasing hormone receptor in the control of myometrial contractility. Endocrinology. 2004 ; 145: 890-900.
21. Sasaki A., Shinkawa O., Margioris AN, et al. Immunoreactive corticotropin-releasing hormone in human plasma during pregnancy, labor and delivery. J Clin Endocrinol Metab. 1987 ; 64: 224-229.
22. Warren WB, Patrick SL, Goland RS Elevated maternal plasma corticotropin-releasing hormone levels in pregnancies complicated by preterm labor. Am J Obstet Gynecol. 1992 ; 166: 1198-1204.
23. Grammatopoulos D., Dai Y., Chen J., et al. Human corticotropin-releasing hormone receptor: difference in subtype expression between pregnant and nonpregnant myometria. J Clin Endocrinol Metab. 1998 ; 83: 2539-2544.
24. Rodriguez-Linares B., Linton EA, Phaneuf S. Expression of corticotrophin-releasing hormone receptor mRNA and protein in the human myometrium. J Endocrinol. 1998 ; 156: 15-21.
25. Wetzka B., Sehringer B., Schäfer WR, et al. Expression patterns of CRH, CRH receptors, and CRH binding protein in human gestational tissue at term. Exp Clin Endocrinol Diabetes. 2003 ; 111: 154-161.
26. Aggelidou E., Hillhouse EW, Grammatopoulos D. Up-regulation of nitric oxide synthase and modulation of the guanylate cyclase activity by corticotrophin-releasing hormone but not urocortin II or urocortin III in cultured human pregnant myometrial cells. Proc Natl Acad Sci U S A. 2002 ; 99: 3300-3305.
27. Hillhouse EW, Grammatopoulos D. Control of intracellular signaling by corticotropin-releasing hormone in human myometrium. Front Horm Res. 2001 ; 27: 66-74.
28. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987 ; 162: 156-159.
29. Kateris E., Papadopoulou N., Grammatopoulos DK, Hillhouse EW Expression and signaling characteristics of the corticotrophin-releasing hormone receptors during the implantation phase in the human endometrium. J Mol Endocrinol. 2004 ; 32: 21-32.
30. Livak KJ, Schmittgen TD Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001 ; 25: 402-408.
31. Pisarchik A., Slominski A. Molecular and functional characterization of novel CRFR1 isoforms from the skin. Eur J Biochem. 2004 ; 271: 2821-2830.
32. Stevens MY, Challis Jrg, Lye SJ Corticotropin-releasing hormone receptor subtype 1 is significantly up-regulated at the time of labor in the human myometrium. J Clin Endocrinol Metab. 1998 ; 83: 4107-4115.
33. Grammatopoulos D., Dai Y., Randeva HS, et al. A novel spliced variant of the type 1 corticotropin-releasing hormone receptor with a deletion in the seventh transmembrane domain present in the human pregnant term myometrium and fetal membranes. Mol Endocrinol. 1999 ; 13: 2189-2202.
34. Sirianni R., Mayhew BA, Carr BR, Parker CR, Rainey WE Corticotropin-releasing hormone (CRH) and urocortin act through type 1 CRH receptors to stimulate dehydroepiandrosterone sulfate production in human fetal adrenal cells. J Clin Endocrinol Metab. 2005 ; 90: 5393-5400.
35. Karteris E., Goumenou A., Koumantakis E., Hillhouse EW, Grammatopoulos DK Reduced expression of corticotropin-releasing hormone receptor type-1α in human preeclamptic and growth-restricted placentas. J Clin Endocrinol Metab. 2003 ; 88: 363-370.
36. Grammatopoulos DK, Randeva HS, Levine MA, Katsanou ES, Hillhouse EW Urocortin, but not corticotropin-releasing hormone (CRH), activates the mitogen-activated protein kinase signal transduction pathway in human pregnant myometrium: an effect mediated via R1alpha and R2beta CRH receptor subtypes and stimulation of Gq-proteins. Mol Endocrinol. 2000 ; 14: 2076-2091.
37. Wille S., Sydow S., Palchaudhuri MR, Spiess J., Dautzenberg FM Identification of amino acids in the N-terminal domain of corticotropin- releasing factor receptor 1 that are important determinants of high-affinity ligand binding. J Neurochem. 1999 ; 72: 388-395.
38. Hillhouse EW, Grammatopoulos DK The molecular mechanisms underlying the regulation of the biological activity of corticotropin-releasing hormone receptors: implications for physiology and pathophysiology. Endocr Rev. 2006 ; 27: 260-286.