Baicalein inhibits IL-1β- and TNF-α-induced inflammatory cytokine production from human mast cells via regulation of the NF-κB pathway

Clinical and Molecular Allergy

Volumn 5, Issue , 2007, Pages

  Hsieh, Chia Jung ^a   Hall, Kenton ^a   Ha, Tuanzhu ^a   Li, Chuanfu ^a   Krishnaswamy, Guha ^a   Chi, David S ^a  

^a East Tennessee State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BAICALEIN; CYTOKINE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; MAST CELL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 38449116664     PISSN: None     EISSN: 14767961     Source Type: Journal    
DOI: 10.1186/1476-7961-5-5     Document Type: Article

References (48)

1. Krishnaswamy G Kelley J Johnson D Youngberg G Stone W Huang SK Bieber J Chi DS The human mast cell: Functions in physiology and disease Front Biosci 2001, 6: D1109-1127. 10.2741/krishnas 11532608
2. Krishnaswamy G Ajitawi O Chi DS The human mast cell: An overview Methods Mol Biol 2006, 315:13-34. 16110146
3. Metz M Grimbaldeston MA Nakae S Piliponsky AM Tsai M Galli SJ Mast cells in the promotion and limitation of chronic inflammation Immunol Rev 2007, 217:304- 328. 10.1111/j.1600-065X.2007.00520.x 17498068
4. Igarashi Y Goldrich MS Kaliner MA Irani AM Schwartz LB White MV Quantitation of inflammatory cells in the nasal mucosa of patients with allergic rhinitis and normal subjects J Allergy Clin Immunol 1995, 95:716-725. 10.1016/S0091-6749(95)70177-X 7897155
5. Brightling CE Symon FA Birring SS Bradding P Wardlaw AJ Pavord ID Comparison of airway immunopathology of eosinophilic bronchitis and asthma Thorax 2003 58: 528-532. 10.1136/thorax.58.6.528 12775868
6. Garriga MM Friedman MM Metcalfe DD A survey of the number and distribution of mast cells in the skin of patients with mast cell disorders J Allergy Clin Immunol 1988, 82:425-432. 10.1016/ 0091-6749(88)90015-2 3170991
7. Lee DM Friend DS Gurish MF Benoist C Mathis D Brenner MB Mast cells: A cellular link between autoantibodies and inflammatory arthritis Science 2002, 297:1689-1692. 10.1126/science.1073176 12215644
8. Castells M Mast cell mediators in allergic inflammation and mastocytosis Immunol Allergy Clin North Am 2006, 26:465-485. 10.1016/ j.iac.2006.05.005 16931289
9. Baumann H Jahreis GP Sauder DN Koj A Human keratinocytes and monocytes release factors which regulate the synthesis of major acute phase plasma proteins in hepatic cells from man, rat, and mouse J Biol Chem 1984, 259:7331-7342. 6202694
10. Okada M Sakaguchi N Yoshimura N Hara H Shimizu K Yoshida N Yoshizaki K Kishimoto S Yamamura Y Kishimoto T B cell growth factors and B cell differentiation factor from human T hybridomas. Two distinct kinds of B cell growth factor and their synergism in B cell proliferation J Exp Med 1983, 157:583-590. 10.1084/jem.157.2.583 6600487
11. Hack CE Aarden LA Thijs LG Role of cytokines in sepsis Adv Immunol 1997, 66:101-195. 9328641
12. Gu L Tseng SC Rollins BJ Monocyte chemoattractant protein-1 Chem Immunol 1999, 72:7-29. 10550927
13. Matsushima K Larsen CG DuBois GC Oppenheim JJ Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line J Exp Med 1989, 169:1485-1490. 10.1084/jem.169.4.1485 2926331
14. Yoshimura T Robinson EA Tanaka S Appella E Kuratsu J Leonard EJ Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants J Exp Med 1989, 169:1449-1459. 10.1084/ jem.169.4.1449 2926329
15. Cannon JG Evans WJ Hughes VA Meredith CN Dinarello CA Physiological mechanisms contributing to increased interleukin-1 secretion J Appl Physiol 1986, 61:1869-1874. 3491062
16. Pennica D Nedwin GE Hayflick JS Seeburg PH Derynck R Palladino MA Kohr WJ Aggarwal BB Goeddel DV Human tumour necrosis factor: Precursor structure, expression and homology to lymphotoxin Nature 1984, 312:724-729. 10.1038/312724a0 6392892
17. Old LJ Tumor necrosis factor (TNF) Science 1985, 230:630-632 10.1126/ science.2413547 2413547
18. Chi DS Fitzgerald SM Pitts S Cantor K King E Lee SA Huang SK Krishnaswamy G MAPK-dependent regulation of IL-1- and beta-adrenoreceptor-induced inflammatory cytokine production from mast cells: Implications for the stress response BMC Immunol 2004, 5:22. 521685 15383152 10.1186/1471-2172-5-22
19. Lee SA Fitzgerald SM Huang SK Li C Chi DS Milhorn DM Krishnaswamy G Molecular regulation of interleukin-13 and monocyte chemoattractant protein-1 expression in human mast cells by interleukin-1beta Am J Respir Cell Mol Biol 2004, 31:283- 291. 10.1165/rcmb.2004-0089OC 15191916
20. Lin CC Shieh DE The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin Am J Chin Med 1996, 24:31-36. 10.1142/S0192415X96000050 8739179
21. Wakabayashi I Inhibitory effects of baicalein and wogonin on lipopolysaccharide-induced nitric oxide production in macrophages Pharmacol Toxicol 1999, 84:288-291. 10401731
22. Li FQ Wang T Pei Z Liu B Hong JS Inhibition of microglial activation by the herbal flavonoid baicalein attenuates inflammation-mediated degeneration of dopaminergic neurons J Neural Transm 2005, 112:331-347. 10.1007/s00702-004-0213-0 15503194
23. Woo KJ Lim JH Suh SI Kwon YK Shin SW Kim SC Choi YH Park JW Kwon TK Differential inhibitory effects of baicalein and baicalin on LPS-induced cyclooxygenase-2 expression through inhibition of C/EBPbeta DNA-binding activity Immunobiology 2006, 211:359-368. 10.1016/j.imbio.2006.02.002 16716805
24. Cheng PY Lee YM Wu YS Chang TW Jin JS Yen MH Protective effect of baicalein against endotoxic shock in rats in vivo and in vitro Biochem Pharmacol 2007, 73:793-804. 10.1016/j.bcp.2006.11.025 17182007
25. Fitzgerald SM Lee SA Hall HK Chi DS Krishnaswamy G Human lung fibroblasts express interleukin-6 in response to signaling after mast cell contact Am J Respir Cell Mol Biol 2004, 30:585-593. 10.1165/ rcmb.2003-0282OC 14565941
26. Fitzgerald SM Chi DS Hall HK Reynolds SA Aramide O Lee SA Krishnaswamy G GM-CSF induction in human lung fibroblasts by IL-1beta, TNF-alpha, and macrophage contact J Interferon Cytokine Res 2003, 23:57-65. 10.1089/ 107999003321455453 12744771
27. Li C Browder W Kao RL Early activation of transcription factor NF-kappaB during ischemia in perfused rat heart Am J Physiol 1999, 276: H543-552. 9950856
28. Li C Ha T Kelley J Gao X Qiu Y Kao RL Browder W Williams DL Modulating Toll-like receptor mediated signaling by (1→3)-beta-D-glucan rapidly induces cardioprotection Cardiovasc Res 2004, 61:538-547. 10.1016/ j.cardiores.2003.09.007 14962484
29. Li C Kao RL Ha T Kelley J Browder IW Williams DL Early activation of IKKbeta during in vivo myocardial ischemia Am J Physiol Heart Circ Physiol 2001, 280:H1264-1271. 11179072
30. Li C Ha T Liu L Browder W Kao RL Adenosine prevents activation of transcription factor NF-kappa B and enhances activator protein-1 binding activity in ischemic rat heart Surgery 2000, 127:161-169. 10.1067/ msy.2000.101582 10686981
31. Hsieh CJ Hall K Krishnaswamy G Chi DS Differential effects of berberine, baicalein, and triptolide on cytokine production from IL-1 -activated mast cells [abstract] J Immunol 2007, 178:95.28.
32. Baeuerle PA Baltimore D NF-kappa B: Ten years after Cell 1996, 87:13- 20. 10.1016/S0092-8674(00)81318-5 8858144
33. Baldwin AS Jr The NF-kappa B and I kappa B proteins: New discoveries and insights Annu Rev Immunol 1996, 14:649-683. 10.1146/ annurev.immunol.14.1.649 8717528
34. Baeuerle PA Baichwal VR NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules Adv Immunol 1997, 65:111-137. 9238509
35. Henz BM Maurer M Lippert U Worm M Babina M Mast cells as initiators of immunity and host defense Exp Dermatol 2001, 10:1-10. 10.1034/ j.1600-0625.2001.100101.x 11168574
36. Kempuraj D Castellani ML Petrarca C Frydas S Conti P Theoharides TC Vecchiet J Inhibitory effect of quercetin on tryptase and interleukin-6 release, and histidine decarboxylase mRNA transcription by human mast cell-1 cell line Clin Exp Med 2006, 6:150-156. 10.1007/s10238-006-0114-7 17191106
37. Castellani ML Kempuraj D Frydas S Theoharides TC Simeonidou I Conti P Vecchiet J Inhibitory effect of quercetin on tryptase and MCP-1 chemokine release, and histidine decarboxylase mRNA transcription by human mast cell-1 cell line Neuroimmunomodulation 2006, 13:179-186. 10.1159/000098131 17191019
38. Kandere-Grzybowska K Kempuraj D Cao J Cetrulo CL Theoharides TC Regulation of IL-1-induced selective IL-6 release from human mast cells and inhibition by quercetin Br J Pharmacol 2006, 148:208-215. 10.1038/ sj.bjp.0706695 16532021
39. Bonnert TP Garka KE Parnet P Sonoda G Testa JR Sims JE The cloning and characterization of human MyD88: A member of an IL-1 receptor related family FEBS Lett 1997, 402:81-84. 10.1016/S0014-5793(96)01506-2 9013863
40. Burns K Martinon F Esslinger C Pahl H Schneider P Bodmer JL Di Marco F French L Tschopp J MyD88, an adapter protein involved in interleukin-1 signaling J Biol Chem 1998, 273:12203-12209. 10.1074/jbc.273.20.12203 9575168
41. Jobin C Bradham CA Russo MP Juma B Narula AS Brenner DA Sartor RB Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity J Immunol 1999, 163:3474-3483, 10477620
42. Scheinman RI Cogswell PC Lofquist AK Baldwin AS Jr Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids Science 1995, 270:283-286. 10.1126/ science.270.5234.283 7569975
43. Kuhn H O'Donnell VB Inflammation and immune regulation by 12/ 15-lipoxygenases Prog Lipid Res 2006, 45:334-356. 10.1016/ j.plipres.2006.02.003 16678271
44. George J Afek A Shaish A Levkovitz H Bloom N Cyrus T Zhao L Funk CD Sigal E Harats D 12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient mice Circulation 2001, 104:1646-1650. 10.1161/hc3901.095772 11581143
45. Matsuyama M Yoshimura R Mitsuhashi M Hase T Tsuchida K Takemoto Y Kawahito Y Sano H Nakatani T Expression of lipoxygenase in human prostate cancer and growth reduction by its inhibitors Int J Oncol 2004, 24:821-827. 15010818
46. Yuan Z Liu Y Liu Y Zhang J Kishimoto C Wang Y Ma A Liu Z Cardioprotective effects of peroxisome proliferator activated receptor gamma activators on acute myocarditis: Anti-inflammatory actions associated with nuclear factor kappaB blockade Heart 2005, 91:1203-1208. 10.1136/hrt.2004.046292 15774612
47. Nakajima A Wada K Miki H Kubota N Nakajima N Terauchi Y Ohnishi S Saubermann LJ Kadowaki T Blumberg RS Nagai R Matsuhashi N Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury Gastroenterology 2001, 120:460-469. 10.1053/ gast.2001.21191 11159886
48. Appel S Mirakaj V Bringmann A Weck MM Grunebach F Brossart P PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways Blood 2005, 106:3888-3894. 10.1182/blood-2004-12-4709 16105976