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Volumn 100, Issue 2, 2008, Pages 81-83

Neuropilin-2: A new molecular target for antiangiogenic and antitumor strategies

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; LIPOSOME; NEUROPILIN 1; NEUROPILIN 2; PLACENTAL GROWTH FACTOR; SEMAPHORIN 3A; SEMAPHORIN 3F; SMALL INTERFERING RNA; SORAFENIB; SUNITINIB; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN B; VASCULOTROPIN D; VASCULOTROPIN E; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; SEMAPHORIN; VASCULOTROPIN RECEPTOR;

EID: 38449115632     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djm305     Document Type: Editorial
Times cited : (9)

References (31)
  • 1
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000;100(1):57-70.
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer. 2003;3(6):401-410.
    • (2003) Nat Rev Cancer , vol.3 , Issue.6 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 3
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med. 1971;285(21):1182-1186.
    • (1971) N Engl J Med , vol.285 , Issue.21 , pp. 1182-1186
    • Folkman, J.1
  • 4
    • 34447108810 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Biology and therapeutic applications
    • Ho QT, Kuo CJ. Vascular endothelial growth factor: biology and therapeutic applications. Int J Biochem Cell Biol. 2007;39(7-8):1349- 1357.
    • (2007) Int J Biochem Cell Biol , vol.39 , Issue.7-8 , pp. 1349-1357
    • Ho, Q.T.1    Kuo, C.J.2
  • 5
    • 34047222738 scopus 로고    scopus 로고
    • Recent progress in the management of advanced renal cell carcinoma
    • Garcia JA, Rini BI. Recent progress in the management of advanced renal cell carcinoma. CA Cancer J Clin. 2007;57(2):112-125.
    • (2007) CA Cancer J Clin , vol.57 , Issue.2 , pp. 112-125
    • Garcia, J.A.1    Rini, B.I.2
  • 6
    • 30744449235 scopus 로고    scopus 로고
    • Angiogenesis as a therapeutic target
    • Ferrara N, Kerbel RS. Angiogenesis as a therapeutic target. Nature. 2005;438(7070):967-974.
    • (2005) Nature , vol.438 , Issue.7070 , pp. 967-974
    • Ferrara, N.1    Kerbel, R.S.2
  • 7
    • 33746548452 scopus 로고    scopus 로고
    • Predicting benefit from anti-angiogenic agents in malignancy
    • Jubb AM, Oates AJ, Holden S, Koeppen H. Predicting benefit from anti-angiogenic agents in malignancy. Nat Rev Cancer. 2006;6(8):626-635.
    • (2006) Nat Rev Cancer , vol.6 , Issue.8 , pp. 626-635
    • Jubb, A.M.1    Oates, A.J.2    Holden, S.3    Koeppen, H.4
  • 8
    • 33749441325 scopus 로고    scopus 로고
    • Rapid vascular regrowth in tumors after reversal of VEGF inhibition
    • Mancuso MR, Davis R, Norberg SM, et al. Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J Clin Invest. 2006;116(10):2610- 2621.
    • (2006) J Clin Invest , vol.116 , Issue.10 , pp. 2610-2621
    • Mancuso, M.R.1    Davis, R.2    Norberg, S.M.3
  • 9
    • 30944446883 scopus 로고    scopus 로고
    • Lessons from phase III clinical trials on anti-VEGF therapy for cancer
    • Jain RK, Duda DG, Clark JW, Loeffler JS. Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nat Clin Pract Oncol. 2006;3(1):24-40.
    • (2006) Nat Clin Pract Oncol , vol.3 , Issue.1 , pp. 24-40
    • Jain, R.K.1    Duda, D.G.2    Clark, J.W.3    Loeffler, J.S.4
  • 10
    • 38449095310 scopus 로고    scopus 로고
    • Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver
    • Gray MJ, Van Buren G, Dallas NA, et al. Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver. J Natl Cancer Inst. 2008;100(2):109-120.
    • (2008) J Natl Cancer Inst , vol.100 , Issue.2 , pp. 109-120
    • Gray, M.J.1    Van Buren, G.2    Dallas, N.A.3
  • 11
    • 0036139515 scopus 로고    scopus 로고
    • The neuropilins: Multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis
    • Neufeld G, Cohen T, Shraga N, Lange T, Kessler O, Herzog Y. The neuropilins: multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis. Trends Cardiovasc Med. 2002;12(1):13-19.
    • (2002) Trends Cardiovasc Med , vol.12 , Issue.1 , pp. 13-19
    • Neufeld, G.1    Cohen, T.2    Shraga, N.3    Lange, T.4    Kessler, O.5    Herzog, Y.6
  • 12
    • 33344474679 scopus 로고    scopus 로고
    • Bielenberg DR, Pettaway CA, Takashima S, Klagsbrun M. Neuropilins in neoplasms: expression, regulation, and function. Exp Cell Res. 2006;312(5):584-593.
    • Bielenberg DR, Pettaway CA, Takashima S, Klagsbrun M. Neuropilins in neoplasms: expression, regulation, and function. Exp Cell Res. 2006;312(5):584-593.
  • 13
    • 0036933684 scopus 로고    scopus 로고
    • The role of neuropilin in vascular and tumor biology
    • Klagsbrun M, Takashima S, Mamluk R. The role of neuropilin in vascular and tumor biology. Adv Exp Med Biol. 2002;515:33-48.
    • (2002) Adv Exp Med Biol , vol.515 , pp. 33-48
    • Klagsbrun, M.1    Takashima, S.2    Mamluk, R.3
  • 14
    • 0034756449 scopus 로고    scopus 로고
    • Differential expression of neuropilin-1 and neuropilin-2 in arteries and veins
    • Herzog Y, Kalcheim C, Kahane N, Reshef R, Neufeld G. Differential expression of neuropilin-1 and neuropilin-2 in arteries and veins. Mech Dev. 2001;109(1):115-119.
    • (2001) Mech Dev , vol.109 , Issue.1 , pp. 115-119
    • Herzog, Y.1    Kalcheim, C.2    Kahane, N.3    Reshef, R.4    Neufeld, G.5
  • 15
    • 0036803751 scopus 로고    scopus 로고
    • Abnormal lymphatic vessel development in neuropilin 2 mutant mice
    • Yuan L, Moyon D, Pardanaud L, et al. Abnormal lymphatic vessel development in neuropilin 2 mutant mice. Development. 2002;129(20):4797-4806.
    • (2002) Development , vol.129 , Issue.20 , pp. 4797-4806
    • Yuan, L.1    Moyon, D.2    Pardanaud, L.3
  • 16
    • 0038686623 scopus 로고    scopus 로고
    • Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development
    • Gu C, Rodriguez ER, Reimert DV, et al. Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev Cell. 2003;5(1):45-57.
    • (2003) Dev Cell , vol.5 , Issue.1 , pp. 45-57
    • Gu, C.1    Rodriguez, E.R.2    Reimert, D.V.3
  • 17
    • 0032707249 scopus 로고    scopus 로고
    • A requirement for neuropilin-1 in embryonic vessel formation
    • Kawasaki T, Kitsukawa T, Bekku Y, et al. A requirement for neuropilin-1 in embryonic vessel formation. Development. 1999;126(21):4895-4902.
    • (1999) Development , vol.126 , Issue.21 , pp. 4895-4902
    • Kawasaki, T.1    Kitsukawa, T.2    Bekku, Y.3
  • 18
    • 0037133617 scopus 로고    scopus 로고
    • Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis
    • Takashima S, Kitakaze M, Asakura M, et al. Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis. Proc Natl Acad Sci USA. 2002;99(6):3657-3662.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.6 , pp. 3657-3662
    • Takashima, S.1    Kitakaze, M.2    Asakura, M.3
  • 19
    • 7444228009 scopus 로고    scopus 로고
    • Deficiency of neuropilin 2 suppresses VEGF-induced retinal neovascularization
    • Shen J, Samul R, Zimmer J, et al. Deficiency of neuropilin 2 suppresses VEGF-induced retinal neovascularization. Mol Med. 2004;10(1-6):12-18.
    • (2004) Mol Med , vol.10 , Issue.1-6 , pp. 12-18
    • Shen, J.1    Samul, R.2    Zimmer, J.3
  • 20
    • 33845991161 scopus 로고    scopus 로고
    • Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth
    • Pan Q, Chanthery Y, Liang WC, et al. Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth. Cancer Cell. 2007;11(1):53-67.
    • (2007) Cancer Cell , vol.11 , Issue.1 , pp. 53-67
    • Pan, Q.1    Chanthery, Y.2    Liang, W.C.3
  • 21
    • 33745063095 scopus 로고    scopus 로고
    • The role of neuropilins in cancer
    • Ellis LM. The role of neuropilins in cancer. Mol Cancer Ther. 2006;5(5):1099-1107.
    • (2006) Mol Cancer Ther , vol.5 , Issue.5 , pp. 1099-1107
    • Ellis, L.M.1
  • 22
    • 34347332447 scopus 로고    scopus 로고
    • Staton CA, Kumar I, Reed MW, Brown NJ. Neuropilins in physiological and pathological angiogenesis. J Pathol. 2007;212(3):237-248.
    • Staton CA, Kumar I, Reed MW, Brown NJ. Neuropilins in physiological and pathological angiogenesis. J Pathol. 2007;212(3):237-248.
  • 23
    • 0036009760 scopus 로고    scopus 로고
    • VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding
    • Soker S, Miao HQ, Nomi M, Takashima S, Klagsbrun M. VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding. J Cell Biochem. 2002;85(2):357-368.
    • (2002) J Cell Biochem , vol.85 , Issue.2 , pp. 357-368
    • Soker, S.1    Miao, H.Q.2    Nomi, M.3    Takashima, S.4    Klagsbrun, M.5
  • 24
    • 0034688995 scopus 로고    scopus 로고
    • Determination of cell adhesion sites of neuropilin-1
    • Shimizu M, Murakami Y, Suto F, Fujisawa H. Determination of cell adhesion sites of neuropilin-1. J Cell Biol. 2000;148(6):1283-1293.
    • (2000) J Cell Biol , vol.148 , Issue.6 , pp. 1283-1293
    • Shimizu, M.1    Murakami, Y.2    Suto, F.3    Fujisawa, H.4
  • 25
    • 14944344614 scopus 로고    scopus 로고
    • Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2
    • Murga M, Fernandez-Capetillo O, Tosato G. Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2. Blood. 2005;105(5):1992-1999.
    • (2005) Blood , vol.105 , Issue.5 , pp. 1992-1999
    • Murga, M.1    Fernandez-Capetillo, O.2    Tosato, G.3
  • 26
    • 34248353061 scopus 로고    scopus 로고
    • Neuropilin-1 promotes unlimited growth of ovarian cancer by evading contact inhibition
    • Baba T, Kariya M, Higuchi T, et al. Neuropilin-1 promotes unlimited growth of ovarian cancer by evading contact inhibition. Gynecol Oncol. 2007;105(3):703-711.
    • (2007) Gynecol Oncol , vol.105 , Issue.3 , pp. 703-711
    • Baba, T.1    Kariya, M.2    Higuchi, T.3
  • 27
    • 85047693077 scopus 로고    scopus 로고
    • Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype
    • Bielenberg DR, Hida Y, Shimizu A, et al. Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype. J Clin Invest. 2004;114(9):1260-1271.
    • (2004) J Clin Invest , vol.114 , Issue.9 , pp. 1260-1271
    • Bielenberg, D.R.1    Hida, Y.2    Shimizu, A.3
  • 28
    • 33646552427 scopus 로고    scopus 로고
    • Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A
    • Narazaki M, Tosato G. Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A. Blood. 2006;107(10):3892-3901.
    • (2006) Blood , vol.107 , Issue.10 , pp. 3892-3901
    • Narazaki, M.1    Tosato, G.2
  • 29
    • 34548839104 scopus 로고    scopus 로고
    • Semaphorin-3A and semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis
    • Guttmann-Raviv N, Shraga-Heled N, Varshavsky A, Guimaraes-Sternberg C, Kessler O, Neufeld G. Semaphorin-3A and semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis. J Biol Chem. 2007;282(36):26294-26305.
    • (2007) J Biol Chem , vol.282 , Issue.36 , pp. 26294-26305
    • Guttmann-Raviv, N.1    Shraga-Heled, N.2    Varshavsky, A.3    Guimaraes-Sternberg, C.4    Kessler, O.5    Neufeld, G.6
  • 30
    • 0036941611 scopus 로고    scopus 로고
    • Neuropilin and its ligands in normal lung and cancer
    • Roche J, Drabkin H, Brambilla E. Neuropilin and its ligands in normal lung and cancer. Adv Exp Med Biol. 2002;515:103-114.
    • (2002) Adv Exp Med Biol , vol.515 , pp. 103-114
    • Roche, J.1    Drabkin, H.2    Brambilla, E.3
  • 31
    • 34548735409 scopus 로고    scopus 로고
    • Semaphorin SEMA3F affects multiple signaling pathways in lung cancer cells
    • Potiron VA, Sharma G, Nasarre P, et al. Semaphorin SEMA3F affects multiple signaling pathways in lung cancer cells. Cancer Res. 2007;67(18):8708-8715.
    • (2007) Cancer Res , vol.67 , Issue.18 , pp. 8708-8715
    • Potiron, V.A.1    Sharma, G.2    Nasarre, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.