메뉴 건너뛰기




Volumn 13, Issue 5, 2007, Pages 276-281

An update on treatment advances for the first-line therapy of metastatic colorectal cancer

Author keywords

Cancer; Colorectal; First line; Metastic

Indexed keywords

ANTIHYPERTENSIVE AGENT; BEVACIZUMAB; BIOLOGICAL MARKER; CAPECITABINE; CELECOXIB; CETUXIMAB; CYTOTOXIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN; PANITUMUMAB; RALTITREXED; VASCULOTROPIN; VASCULOTROPIN A; ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR; MONOCLONAL ANTIBODY;

EID: 38449099720     PISSN: 15289117     EISSN: 1540336X     Source Type: Journal    
DOI: 10.1097/PPO.0b013e3181570062     Document Type: Review
Times cited : (43)

References (27)
  • 2
    • 13744251436 scopus 로고    scopus 로고
    • Systemic therapy for colorectal cancer
    • Meyerhardt JA, Mayer RJ. Systemic therapy for colorectal cancer. N Engl J Med. 2005;352:476-487.
    • (2005) N Engl J Med , vol.352 , pp. 476-487
    • Meyerhardt, J.A.1    Mayer, R.J.2
  • 4
    • 0033874892 scopus 로고    scopus 로고
    • Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
    • de Gramont A, Figer A, Seymour M, et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol. 2000;18:2938-2947.
    • (2000) J Clin Oncol , vol.18 , pp. 2938-2947
    • de Gramont, A.1    Figer, A.2    Seymour, M.3
  • 5
    • 1842569206 scopus 로고    scopus 로고
    • A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
    • Goldberg RM, Sargent DJ, Morton RF, et al. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol. 2004;22:23-30.
    • (2004) J Clin Oncol , vol.22 , pp. 23-30
    • Goldberg, R.M.1    Sargent, D.J.2    Morton, R.F.3
  • 6
    • 1342290189 scopus 로고    scopus 로고
    • FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
    • Tournigand C, Andre T, Achille E, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol. 2004;22:229-237.
    • (2004) J Clin Oncol , vol.22 , pp. 229-237
    • Tournigand, C.1    Andre, T.2    Achille, E.3
  • 7
    • 24644457747 scopus 로고    scopus 로고
    • Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A multicenter study of the Gruppo Oncologico Dell'Italia Me-ridionale
    • Colucci G, Gebbia V, Paoletti G, et al. Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Me-ridionale. J Clin Oncol. 2005;23:4866-4875.
    • (2005) J Clin Oncol , vol.23 , pp. 4866-4875
    • Colucci, G.1    Gebbia, V.2    Paoletti, G.3
  • 8
    • 33750905700 scopus 로고    scopus 로고
    • Phase III study of irinotecan/ 5FU/LV (FOLFIRI) or oxaliplatin/5FU/LV (FOLFOX) ± cetuximab for patients (pts) with untreated metastatic adenocarcinoma of the colon or rectum (MCRC): CALGB 80203 preliminary results
    • Venook A, Niedzwiecki D, Hollis D, et al. Phase III study of irinotecan/ 5FU/LV (FOLFIRI) or oxaliplatin/5FU/LV (FOLFOX) ± cetuximab for patients (pts) with untreated metastatic adenocarcinoma of the colon or rectum (MCRC): CALGB 80203 preliminary results. J Clin Oncol. 2006;24(18 suppl):3509.
    • (2006) J Clin Oncol , vol.24 , Issue.18 SUPPL. , pp. 3509
    • Venook, A.1    Niedzwiecki, D.2    Hollis, D.3
  • 9
    • 67649916894 scopus 로고    scopus 로고
    • Porschen R, Arkenau H, Kubicka S, et al. Capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin: a randomized comparison in metastatic colorectal cancer - a final report of the AIO Colorectal Study Group. J Clin Oncol. 2007; July 11 (Epub ahead of print).
    • Porschen R, Arkenau H, Kubicka S, et al. Capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin: a randomized comparison in metastatic colorectal cancer - a final report of the AIO Colorectal Study Group. J Clin Oncol. 2007; July 11 (Epub ahead of print).
  • 10
    • 34250378102 scopus 로고    scopus 로고
    • XELOX vs. FOLFOX4: Efficacy results from XELOX-1/NO16966, a randomized phase III trial in first-line metastatic colorectal cancer (MCRC)
    • Cassidy J, Clarke S, Diaz-Rubio E, et al. XELOX vs. FOLFOX4: efficacy results from XELOX-1/NO16966, a randomized phase III trial in first-line metastatic colorectal cancer (MCRC). Proc Am Soc Clin Oncol. 2007;25(18 suppl):4030.
    • (2007) Proc Am Soc Clin Oncol , vol.25 , Issue.18 SUPPL. , pp. 4030
    • Cassidy, J.1    Clarke, S.2    Diaz-Rubio, E.3
  • 11
    • 34848835988 scopus 로고    scopus 로고
    • Bevacizumab (Bev) in combination with XELOX or FOLFOX4: Updated efficacy results from XELOX-1/NO16966, a randomized phase III trial in first-line metastatic colorectal cancer
    • Saltz L, Clarke S, Diaz-Rubio E, et al. Bevacizumab (Bev) in combination with XELOX or FOLFOX4: updated efficacy results from XELOX-1/NO16966, a randomized phase III trial in first-line metastatic colorectal cancer. Proc Am Soc Clin Oncol. 2007;25(18 suppl):4028.
    • (2007) Proc Am Soc Clin Oncol , vol.25 , Issue.18 SUPPL. , pp. 4028
    • Saltz, L.1    Clarke, S.2    Diaz-Rubio, E.3
  • 12
    • 45749089645 scopus 로고    scopus 로고
    • Efficacy and safety findings from a randomized phase III study of capecitabine (X) + oxaliplatin (O)b (XELOX) vs. infusional 5-FU/LV + O (FOLFOX-6) for metastatic colorectal cancer (MCRC)
    • Ducreux M, Bennouna J, Hebbar M, et al. Efficacy and safety findings from a randomized phase III study of capecitabine (X) + oxaliplatin (O)b (XELOX) vs. infusional 5-FU/LV + O (FOLFOX-6) for metastatic colorectal cancer (MCRC). Proc Am Soc Clin Oncol. 2007:25(18 suppl):4029.
    • (2007) Proc Am Soc Clin Oncol , vol.25 , Issue.18 SUPPL. , pp. 4029
    • Ducreux, M.1    Bennouna, J.2    Hebbar, M.3
  • 13
    • 0037425721 scopus 로고    scopus 로고
    • Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: A multicentre randomised trial
    • Maughan TS, James RD, Kerr DJ, et al. Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: a multicentre randomised trial. Lancet. 2003;361:457-464.
    • (2003) Lancet , vol.361 , pp. 457-464
    • Maughan, T.S.1    James, R.D.2    Kerr, D.J.3
  • 14
    • 33644843853 scopus 로고    scopus 로고
    • OPTIMOX1: A randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-go fashion in advanced colorectal cancer - a GERCOR study
    • Tournigand C, Cervantes A, Figer A, et al. OPTIMOX1: a randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-go fashion in advanced colorectal cancer - a GERCOR study. J Clin Oncol. 2006;24:394-400.
    • (2006) J Clin Oncol , vol.24 , pp. 394-400
    • Tournigand, C.1    Cervantes, A.2    Figer, A.3
  • 15
    • 34848850990 scopus 로고    scopus 로고
    • Final results of OPTIMOX2, a large randomized phase II study of maintenance therapy or chemotherapy-free intervals (CFI) after FOLFOX in patients with metastatic colorectal cancer (MRC): A GERCOR study
    • Maindrault-Goebel F, Lledo G, Chibaudel B, et al. Final results of OPTIMOX2, a large randomized phase II study of maintenance therapy or chemotherapy-free intervals (CFI) after FOLFOX in patients with metastatic colorectal cancer (MRC): a GERCOR study. Proc Am Soc Clin Oncol. 2007;25(18 suppl):4013.
    • (2007) Proc Am Soc Clin Oncol , vol.25 , Issue.18 SUPPL. , pp. 4013
    • Maindrault-Goebel, F.1    Lledo, G.2    Chibaudel, B.3
  • 16
    • 13844262927 scopus 로고    scopus 로고
    • Targeting vascular endothelial growth factor and angiogenesis for the treatment of colorectal cancer
    • Collins TS, Hurwitz HI. Targeting vascular endothelial growth factor and angiogenesis for the treatment of colorectal cancer. Semin Oncol. 2005;32:61-68.
    • (2005) Semin Oncol , vol.32 , pp. 61-68
    • Collins, T.S.1    Hurwitz, H.I.2
  • 17
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335-2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 18
    • 20544478429 scopus 로고    scopus 로고
    • Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: Results of a randomized phase II trial
    • Kabbinavar FF, Schulz J, McCleod M, et al. Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial. J Clin Oncol. 2005;24:3697-3705.
    • (2005) J Clin Oncol , vol.24 , pp. 3697-3705
    • Kabbinavar, F.F.1    Schulz, J.2    McCleod, M.3
  • 19
    • 33749016960 scopus 로고    scopus 로고
    • Safety and efficacy of oxaliplatin/fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer (mCRC): Final analysis of the TREE-Study
    • Hochster HS, Hart LL, Ramanathan RK, et al. Safety and efficacy of oxaliplatin/fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer (mCRC): final analysis of the TREE-Study. Proc Am Soc Clin Oncol. 2006;24(18 suppl): 3510.
    • (2006) Proc Am Soc Clin Oncol , vol.24 , Issue.18 SUPPL. , pp. 3510
    • Hochster, H.S.1    Hart, L.L.2    Ramanathan, R.K.3
  • 20
    • 34447280179 scopus 로고    scopus 로고
    • Updated results of BICC-C study comparing firsr-line irinotecan/fluoropyrimidine combinations with or without celecoxib in mCRC: Updated efficacy data
    • Fuchs C, Philip J, Mitchell E, et al. Updated results of BICC-C study comparing firsr-line irinotecan/fluoropyrimidine combinations with or without celecoxib in mCRC: updated efficacy data. Proc Am Soc Clin Oncol. 2007;25:4027.
    • (2007) Proc Am Soc Clin Oncol , vol.25 , pp. 4027
    • Fuchs, C.1    Philip, J.2    Mitchell, E.3
  • 21
    • 39149119830 scopus 로고    scopus 로고
    • Phase II study of infusional 5-fluorouracil, leucovorin and irinotecan (FOLFIRI) plus bevacizumab as first-line treatment for metastatic colorectal cancer
    • Kopetz S, Glover KY, Eng C, et al. Phase II study of infusional 5-fluorouracil, leucovorin and irinotecan (FOLFIRI) plus bevacizumab as first-line treatment for metastatic colorectal cancer. Proc Am Soc Clin Oncol. 2007;25:4089.
    • (2007) Proc Am Soc Clin Oncol , vol.25 , pp. 4089
    • Kopetz, S.1    Glover, K.Y.2    Eng, C.3
  • 22
    • 0041629450 scopus 로고    scopus 로고
    • Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
    • Mendelsohn J, Baselga J. Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol. 2003;21:2787-2799.
    • (2003) J Clin Oncol , vol.21 , pp. 2787-2799
    • Mendelsohn, J.1    Baselga, J.2
  • 23
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med. 2004;351:337-345.
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 24
    • 23844435339 scopus 로고    scopus 로고
    • Cetuximab in combination with oxaliplatin/5-fluorouracil (5-FU)/folinic acid (FA) (FOLFOX-4) in the first-line treatment of patients with epidermal growth factor receptor (EGFR)-expressing metastatic colorectal cancer: An international phase II study
    • Díaz Rubio E, Tabernero J, van Cutsem E, et al. Cetuximab in combination with oxaliplatin/5-fluorouracil (5-FU)/folinic acid (FA) (FOLFOX-4) in the first-line treatment of patients with epidermal growth factor receptor (EGFR)-expressing metastatic colorectal cancer: an international phase II study. Proc Am Soc Clin Oncol. 2005;23:3535.
    • (2005) Proc Am Soc Clin Oncol , vol.23 , pp. 3535
    • Díaz Rubio, E.1    Tabernero, J.2    van Cutsem, E.3
  • 25
    • 34447264101 scopus 로고    scopus 로고
    • Randomized phase III study of irinotecan and 5-FU/FA with or without cetuximab in the first-line treatment of patients with metastatic colorectal cancer (mCRC): The CRYSTAL trial
    • Van Cutsem E, Nowacki M, Lang I, et al. Randomized phase III study of irinotecan and 5-FU/FA with or without cetuximab in the first-line treatment of patients with metastatic colorectal cancer (mCRC): the CRYSTAL trial. Proc Am Soc Clin Oncol. 2007;25:4000.
    • (2007) Proc Am Soc Clin Oncol , vol.25 , pp. 4000
    • Van Cutsem, E.1    Nowacki, M.2    Lang, I.3
  • 26
    • 34147103678 scopus 로고    scopus 로고
    • Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer
    • Van Cutsem E, Peeters M, Siena S, et al. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. J Clin Oncol. 2007;25:1658-1664.
    • (2007) J Clin Oncol , vol.25 , pp. 1658-1664
    • Van Cutsem, E.1    Peeters, M.2    Siena, S.3
  • 27
    • 34247480064 scopus 로고    scopus 로고
    • Panitumumab with irinotecan/ leucovorin/5-fluorouracil for first-line treatment of metastatic colorectal cancer
    • Berlin J, Posey J, Tchekmedvian S, et al. Panitumumab with irinotecan/ leucovorin/5-fluorouracil for first-line treatment of metastatic colorectal cancer. Clin Colorectal Cancer. 2007;6:427-432.
    • (2007) Clin Colorectal Cancer , vol.6 , pp. 427-432
    • Berlin, J.1    Posey, J.2    Tchekmedvian, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.