Low-dose oral vitamin K to normalize the international normalized ratio prior to surgery in patients who require temporary interruption of warfarin

Journal of Thrombosis and Thrombolysis

Volumn 24, Issue 2, 2007, Pages 93-97

  Woods, Karen ^a   Douketis, James D ^a   Kathirgamanathan, Kala ^a   Yi, Qilong ^b   Crowther, Mark A ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Surgery; Vitamin K; Warfarin

Indexed keywords

ANTICOAGULANT AGENT; VITAMIN K GROUP; WARFARIN;

ADULT; AGED; ARTICLE; BLOOD CLOTTING; DRUG CONTRAINDICATION; DRUG EFFECT; DRUG SCREENING; FEMALE; HUMAN; INTERNATIONAL NORMALIZED RATIO; MALE; MIDDLE AGED; ORAL DRUG ADMINISTRATION; PERIOPERATIVE PERIOD; RETROSPECTIVE STUDY;

ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; ANTICOAGULANTS; BLOOD COAGULATION; DRUG EVALUATION; FEMALE; HUMANS; INTERNATIONAL NORMALIZED RATIO; MALE; MIDDLE AGED; PERIOPERATIVE CARE; RETROSPECTIVE STUDIES; VITAMIN K; WARFARIN;

EID: 38449095966     PISSN: 09295305     EISSN: 1573742X     Source Type: Journal    
DOI: 10.1007/s11239-007-0022-z     Document Type: Article

References (10)

1. American Heart Association, Heart Disease and Stroke Statistics Update. 2001: Dallas, Texas
2. Katholi RE, Nolan SP, McGuire LB (1976) Living with prosthetic heart valves. Subsequent noncardiac operations and the risk of thromboembolism or hemorrhage. Am Heart J 92:162-167
3. Tinker JH, Tarhan S (1978) Discontinuing anticoagulant therapy in surgical patients with cardiac valve prostheses. Observations in 180 operations. JAMA 239:738-739 (Pubitemid 8276469)
4. Douketis JD (2002) Perioperative anticoagulation management in patients who are receiving oral anticoagulant therapy: a practical guide for clinicians. Thromb Res 108:3-13 (Pubitemid 36197655)
5. Spyropoulos AC, Turpie AG (2005) Perioperative bridging interruption with heparin for the patient receiving long-term anticoagulation. Curr Opin Pulm Med 11:373-379 (Pubitemid 41291078)
6. Jaffer AK, Brotman DJ, Chukwumerije N (2003) When patients on warfarin need surgery. Cleve Clin J Med 70:973-984 (Pubitemid 37461372)
7. White RH, McKitrick T, Hutchison R, et al (1995) Temporary discontinuation of warfarin therapy: changes in the international normalized ratio. Ann Intern Med 122:40-42
8. Crowther MA, Donavan D, Harrison L, McGinnis J, Ginsberg J (1998) Low-dose oral vitamin K reliably reverses over-anticoagulation due to warfarin. Thromb Haemost 79:1116-1118 (Pubitemid 28297157)
9. Patel RJ, Witt DM, Sasoon JJ, Tillman DJ, Wilkinson DS (2000) Randomized, placebo controlled trial of oral phytonadione for excessive anticoagulation. Pharmotherapy 20:1159-1166
10. Pengo V, Banzato A, Garelli E, Zasso A, Biasiolo A (1993) Reversal of excessive effect of regular anticoagulation: low dose of phytonadione (vitamin K1) compared with warfarin discontinuation. Blood Coagul Fibrinolysis 4:739-741 (Pubitemid 23343397)