Anti-tumor activity of arginine deiminase via arginine deprivation in retinoblastoma

Oncology Reports

Volumn 18, Issue 6, 2007, Pages 1373-1377

  Kim, Jeong Hun ^a   Kim, Jin Hyoung ^a   Yu, Young Suk ^a   Kim, Dong Hun ^b   Min, Bon Hong ^c   Kim, Kyu Won ^a  

^a Seoul National University   (South Korea)

^b Chosun University   (South Korea)

^c Korea University College of Medicine   (South Korea)

Author keywords

Arginine deiminase; Arginine deprivation; Argininosuccinate synthetase; Retinoblastoma

Indexed keywords

ANTINEOPLASTIC AGENT; ARGININE; ARGININE DEIMINASE; ARGININOSUCCINATE SYNTHASE; HYDROLASE; RECOMBINANT PROTEIN;

ADENOCARCINOMA; ARTICLE; BREAST TUMOR; CELL DIVISION; CELL SURVIVAL; ENUCLEATION; ENZYMOLOGY; EYE TUMOR; FEMALE; GENETICS; HUMAN; METABOLISM; PATHOLOGY; RETINOBLASTOMA; TUMOR CELL LINE;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; ARGININE; ARGININOSUCCINATE SYNTHASE; BREAST NEOPLASMS; CELL DIVISION; CELL LINE, TUMOR; CELL SURVIVAL; EYE ENUCLEATION; EYE NEOPLASMS; FEMALE; HUMANS; HYDROLASES; RECOMBINANT PROTEINS; RETINOBLASTOMA;

EID: 38449091831     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.18.6.1373     Document Type: Article

References (32)

1. Abramson DH and Schefler AC: Update on retinoblastoma. Retina 24: 828-848, 2004. (Pubitemid 39657479)
2. DiCiommo D, Gallie BL and Bremner R: Retinoblastoma: the disease, gene and protein provide critical leads to understand cancer. Semin Cancer Biol 10: 255-269, 2000.
3. Beck MN, Balmer A, Dessing C, Pica A and Munier F: First-line chemotherapy with local treatment can prevent external-beam irradiation and enucleation in low-stage intraocular retinoblastoma. J Clin Oncol 18: 2881-2887, 2000. (Pubitemid 30620076)
4. Kim JH, Yu YS, Khwarg SI, Choi HS, Shin HY and Ahn HS: Clinical result of prolonged primary chemotherapy in retinoblastoma patients. Korean J Ophthalmol 17: 35-43, 2003.
5. Rodriguez-Galindo C, Wilson MW, Haik BG, Merchant TE, Billups CA, Shah N, Cain A, Langston J, Lipson M, Kun LE and Pratt CB: Treatment of intraocular retinoblastoma with vincristine and carboplatin. J Clin Oncol 21: 2019-2025, 2003. (Pubitemid 46606392)
6. Shields CL, Shields JA and De Potter P: New treatment modalities for retinoblastoma. Curr Opin Ophthalmol 7: 20-26, 1996. (Pubitemid 26321773)
7. Nishimura S, Sato T, Ueda H and Ueda K: Acute myeloblastic leukemia as a second malignancy in a patient with hereditary retinoblastoma. J Clin Oncol 19: 4182-4183, 2001. (Pubitemid 33049540)
8. Holle LM: Pegaspargase: an alternative? Ann Pharmacother 31: 616-624, 1997.
9. Yoshioka T, Wada T, Uchida N, Maki H, Yoshida H, Ide N, Kasai H, Hojo K, Shono K, Maekawa R, Yagi S, Hoffman RM and Sugita K: Anticancer efficacy in vivo and in vitro, synergy with 5-fluorouracil, and safety of recombinant methioninase. Cancer Res 58: 2583-2587, 1998. (Pubitemid 28275429)
10. Wheatley DN, Scott L, Lamb J and Smith S: Single amino acid (arginine) restriction: growth and death of cultured HeLa and human diploid fibroblasts. Cell Physiol Biochem 10: 37-55, 2000.
11. Takaku H, Takase M, Abe S, Hayashi H and Miyazaki K: In vivo anti-tumor activity of arginine deiminase purified from Mycoplasma arginini. Int J Cancer 51: 244-249, 1992.
12. Komada Y, Zhang XL, Zhou YW, Ido M and Azuma E: Apoptotic cell death of human T lymphoblastoid cells induced by arginine deiminase. Int J Hematol 65: 129-141, 1997. (Pubitemid 27102073)
13. Gong H, Zolzer F, von Recklinghausen G, Havers W and Schweigerer L: Arginine deiminase inhibits proliferation of human leukemia cells more potently than asparaginase by inducing cell cycle arrest and apoptosis. Leukemia 14: 826-829, 2000. (Pubitemid 30235059)
14. Ensor CM, Holtsberg FW, Bomalaski JS and Clark MA: Pegylated arginine deiminase (ADI-SS PEG20,000 mw) inhibits human melanomas and hepatocellular carcinomas in vitro and in vivo. Cancer Res 62: 5443-5450, 2002.
15. Noh EJ, Kang SW, Shin YJ, Choi SH, Kim CG, Park IS, Wheatley DN and Min BH: Arginine deiminase enhances dexamethasone-induced cytotoxicity in human T-lymphoblastic leukemia CCRF-CEM cells. Int J Cancer 112: 502-508, 2004. (Pubitemid 39390617)
16. Yoon CY, Shim YJ, Kim EH, Lee JH, Won NH, Kim JH, Park IS, Yoon DK and Min BH: Renal cell carcinoma does not express argininosuccinate synthetase and is highly sensitive to arginine deprivation via arginine deiminase. Int J Cancer 120: 897-905, 2006.
17. Morris Jr SM: Enzymes of arginine metabolism. J Nutr 134: 2743S-2767S, 2004.
18. Shen LJ, Lin WC, Beloussow K and Shen WC: Resistance to the anti-proliferative activity of recombinant arginine deiminase in cell culture correlates with the endogenous enzyme, argininosuccinate synthetase. Cancer Lett 191: 165-170, 2003. (Pubitemid 36255601)
19. Shields CL, Honavar SG, Meadows AT, Shields JA, Demirci H, Singh A, Friedman DL and Naduvilath TJ: Chemoreduction plus focal therapy for retinoblastoma: Factors predictive of need for treatment with external beam radiotherapy or enucleation. Am J Ophthalmol 133: 657-664, 2002. (Pubitemid 34462014)
20. Greenwald MJ and Strauss LC: Treatment of intraocular retinoblastoma with carboplatin and etoposide chemotherapy. Ophthalmology 103: 1989-1997, 1996. (Pubitemid 27024619)
21. Levy C, Doz F, Quintana E, Pacquement H, Michon J, Schlienger P, Validire P, Asselain B, Desjardins L and Zucker JM: Role of chemotherapy alone or in combination with hyperthermia in the primary treatment of intraocular retinoblastoma: Preliminary results. Br J Ophthalmol 82: 1154-1158, 1998. (Pubitemid 28474871)
22. Friedman DL, Himelstein B, Shields CL, Shields JA, Needle M, Miller D, Bunin GR and Meadows AT: Chemoreduction and local ophthalmic therapy for intraocular retinoblastoma. J Clin Oncol 18: 12-17, 2000. (Pubitemid 30036331)
23. Gallie BL, Budning A, DeBoer G, Thiessen JJ, Koren G, Verjee Z, Ling V and Chan HS: Chemotherapy with focal therapy can cure intraocular retinoblastoma without radiotherapy. Arch Ophthalmol 114: 1321-1328, 1996. (Pubitemid 26398717)
24. Kingston JE, Hungerford JL, Madreperla SA and Plowman PN: Results of combined chemotherapy and radiotherapy for advanced intraocular retinoblastoma. Arch Ophthalmol 114: 1339-1343, 1996. (Pubitemid 26398719)
25. Smith MA, Rubinstein L and Ungerleider RS: Therapy-related acute myeloid leukemia following treatment with epipodophyllotoxins: Estimating the risks. Med Pediatr Oncol 23: 86-98, 1994. (Pubitemid 24213321)
26. Milner JA: Metabolic aberrations associated with arginine deficiency. J Nutr 115: 516-523, 1985.
27. Wheatley DN: Controlling cancer by restricting arginine availability-arginine-catabolizing enzymes as anticancer agents. Anticancer Drugs 15: 825-833, 2004.
28. Rabinovitz M: The pleiotypic response to amino acid deprivation is the result of interactions between components of the glycolysis and protein synthesis pathways. FEBS Lett 302: 113-116, 1992.
29. Lamb J and Wheatley DN: Single amino acid (arginine) deprivation induces G1 arrest associated with inhibition of cdk4 expression in cultured human diploid fibroblasts. Exp Cell Res 255: 238-249, 2000. (Pubitemid 30143857)
30. Scott L, Lamb J, Smith S and Wheatley DN: Single amino acid (arginine) deprivation: rapid and selective death of cultured transformed and malignant cells. Br J Cancer 83: 800-810, 2000.
31. Kang SW, Kang H, Park IS, Choi SH, Shin KH, Chun YS, Chun BG and Min BH: Cytoprotective effect of arginine deiminase on taxol-induced apoptosis in DU145 human prostate cancer cells. Mol Cell 10: 331-337, 2000.
32. Noh EJ, Kang SW, Shin YJ, Kim DC, Park IS, Kim MY, Chun BG and Min BH: Characterization of mycoplasma arginine deiminase expressed in E. coli and its inhibitory regulation of nitric oxide synthesis. Mol Cell 13: 137-143, 2002. (Pubitemid 41583060)