Evaluation of two antimicrobial therapies in the treatment of Leptospira borgpetersenii Serovar hardjo infection in experimentally infected cattle

Veterinary Therapeutics

Volumn 8, Issue 3, 2007, Pages 201-208

  Cortese, Victor S ^a   Behan, Stephen ^a   Galvin, Jeff E ^a   Penka, Dan R ^a   Ramsey, Deborah ^a   Bryson, W Lawrence ^a   Lucas, Merlyn J ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; BOS; LEPTOSPIRA; LEPTOSPIRA BORGPETERSENII SEROVAR HARDJO; SPIROCHAETALES;

ANTIINFECTIVE AGENT; CEFTIOFUR; CEPHALOSPORIN DERIVATIVE; DISACCHARIDE; HETEROCYCLIC COMPOUND; TULATHROMYCIN; UNCLASSIFIED DRUG;

ANIMAL; ANIMAL DISEASE; ARTICLE; CATTLE; CATTLE DISEASE; DRUG EFFECT; FEMALE; LEPTOSPIRA; LEPTOSPIROSIS; RANDOMIZATION; TREATMENT OUTCOME;

ANIMALS; ANTI-BACTERIAL AGENTS; CATTLE; CATTLE DISEASES; CEPHALOSPORINS; DISACCHARIDES; FEMALE; HETEROCYCLIC COMPOUNDS; LEPTOSPIRA; LEPTOSPIROSIS; RANDOM ALLOCATION; TREATMENT OUTCOME;

EID: 38449089623     PISSN: 15283593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Bolin CA: Leptospira interrogans serovar hardjo infection of cattle. Bovine Proc 24:12-14, 1992.
2. Ellis WA, Thiermann AB: Isolation of leptospires from the genital tract of Iowa cows. Am J Vet Res 47:1694-1696, 1986.
3. Ellis WA: Leptospirosis as a cause of reproductive failure. Vet Clin North Am Food Anim Pract 10(3):463-478, 1994.
4. Perino LJ, Rupp GP: Immunization of the beef cow and its influence on fetal and neonatal calf health. Vet Clin North Am Food Anim Pract 10(1): 15-34, 1994.
5. Radostits OM, Blood DC, Gay CC (eds): Diseases caused by Leptospira spp, in Veterinary Medicine, ed 8. London, Bailliere Tindall, 1994, pp 884-908.
6. Data on file, Study Report No. 2943A-60-00-096, Pfizer, Inc.
7. Wikse SE, Rogers GM, Ramachandran S, et al: Herd prevalence and risk factors of Leptospira infection in beef cow/calf operations in the United States: Leptospira borgpetersenii serovar Hardjo. Bovine Pract 41(1): 15-23, 2007
8. Heath SE, Johnson R: Leptospirosis. JAVMA 205(11): 1518-1523, 1994.
9. Miller DA, Wilson MA, Beran GW: Survey to estimate prevalence of Leptospira interrogans infection in mature cattle in the United States. Am J Vet Res 52(11): 1761-1768, 1991.
10. Bolin CA, Alt DP: Use of a monovalent leptospiral vaccine to prevent renal colonization and urinary shedding in cattle exposed to Leptospiral borgpetersenii serovar hardjo. Am J Vet Res 62:995-1000, 2001.
11. Alt DP, Zuerner RL, Bolin CA: Evaluation of antibiotics for treatment of cattle infected with Leptospira borgpetersenii serovar hardjo. JAVMA 219(5):636-639, 2001.
12. Gerritson MJ, Koopmans MJ, Dekker TCEM, et al: Effective treatment with dihydrostreptomycin of naturally infected cows shedding Leptospira interrogans serovar hardjo subtype hardjobovis. Am J Vet Res 55(3): 339-344, 1994.
13. Bolin CA, Thiermann AB, Handsaker AL, Foley JW: Effect of vaccination with a pentavalent leptospiral vaccine on Leptospira interrogans serovar hardjo type hardjo-bovis infection of pregnant cattle. Am J Vet Res 50(1):161-165, 1989.
14. Ellis WA, Montgomery J, Cassells JA: Dihydrostreptomycin treatment of bovine carriers of Leptospira interrogans serovar hardjo. Res Vet Sci 39:292, 1985.
15. Wagenaar J, Zuerner RL, Alt D, Bolin CA: Comparison of polymerase chain reaction assays with bacteriologic culture, immunofluorescence, and nucleic acid hybridization for detection of Leptospira borgpetersenii serovar hardjo in urine of cattle. Am J Vet Res 61(3): 316-320, 2000.
16. Kahn JB: A case of Weil's disease requiring steroid therapy for thrombocytopenia and bleeding. Am J Trop Med Hyg 31:1213-1215, 1982.
17. Gendron V, Prieur J, Gaufroy X, Gras C: Leptospirosis in French Polynesia: 120 case reports. Med Trop 52(1):21-27, 1992.
18. Watt G, Padre LP, Tuazon ML, et al: Placebo-controlled trial of intravenous penicillin for severe and late leptospirosis. Lancet 1(8583):433-435, 1988.
19. Gilks CF, Lambert HF, Broughton BS, Baker CC: Failure of penicillin prophylaxis in laboratory acquired leprospirosis. Postgrad Med J 64(749):236-238, 1988.
20. McClain JB, Ballou WR, Harrison SM, Steinweg DL: Doxycycline therapy for leptospirosis. Ann Intern Med 100(5):696-698, 1984.
21. Thiermarm AB: Leptospirosis: Current developments and trends. JAVMA 184:722-725, 1984.
22. Van Metre DC, Divers TJ: Leptospirosis, in Smith BP (ed): Large Animal Internal Medicine, ed 3. St. Louis, Mosby, 2002, p 871.
23. Bolin CA, Prescott JR: Leptospirosis, in Howard JL, Smith RA (eds): Current Veterinary Therapy 4: Food Animal Practice. Philadelphia, WB Saunders, 1999, pp 352-358.