PTC124, nonsense mutations and Duchenne muscular dystrophy

Neuromuscular Disorders

Volumn 17, Issue 9-10, 2007, Pages 719-720

  Wilton, Steve ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

OXADIAZOLE DERIVATIVE; PTC 124;

ANIMAL; ARTICLE; DRUG ANTAGONISM; DUCHENNE MUSCULAR DYSTROPHY; GENETICS; HUMAN; MOUSE; STOP CODON; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

ANIMALS; CODON, NONSENSE; HUMANS; MICE; MICE, INBRED MDX; MUSCULAR DYSTROPHY, DUCHENNE; OXADIAZOLES;

EID: 38449087274     PISSN: 09608966     EISSN: 18732364     Source Type: Journal    
DOI: 10.1016/j.nmd.2007.07.001     Document Type: Article

References (4)

1. E.M. Welch, E.R. Barton, J. Zhuo, et al. PTC124 targets genetic disorders caused by nonsense mutations, Nature 447 (2007) 87-91.
2. S. Aurino, V. Nigro, Readthrough strategies for stop codons in Duchenne muscular dystrophy, Acta Myologica 25 (2006) 5-12.
3. L. Bidou, I. Hatin, N. Perez, et al. Premature stop codons involved in muscular dystrophies show a broad spectrum of readthrough efficiencies in response to gentamicin treatment, Gene Ther. 11 (2004) 619-627.
4. J.N. Haslett, D. Sanoudou, A.T. Kho, et al. Gene expression comparison of biopsies from Duchenne muscular dystrophy (DMD) and normal skeletal muscle, Proc. Natl. Acad. Sci. 99 (2002) 15000-15005